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Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice

The Journal of clinical investigation, 2010-12, Vol.120 (12), p.4316-4331

2010

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A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange

Nature (London), 2008-11, Vol.456 (7219), p.269-273

2008

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Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in the liver

Journal of hepatology, 2012-01, Vol.56 (1), p.199-209

2012

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Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders

The Journal of physiology, 2006-07, Vol.574 (1), p.41-53

2006

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Hepatic Glucose Sensing via the CREB Coactivator CRTC2

Science (American Association for the Advancement of Science), 2008-03, Vol.319 (5868), p.1402-1405

2008

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The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity

Nature communications, 2018-05, Vol.9 (1), p.2092-18, Article 2092

2018

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The transcription factor ChREBP Orchestrates liver carcinogenesis by coordinating the PI3K/AKT signaling and cancer metabolism

Nature communications, 2024-02, Vol.15 (1), p.1879-1879, Article 1879

2024

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O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver

Diabetes (New York, N.Y.), 2011-05, Vol.60 (5), p.1399-1413

2011

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A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response

Cell reports (Cambridge), 2017-10, Vol.21 (2), p.403-416

2017

Volltextzugriff (PDF)

ChREBP, a transcriptional regulator of glucose and lipid metabolism

Annual review of nutrition, 2007-01, Vol.27 (1), p.179-192

2007

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UCP2 Deficiency Increases Colon Tumorigenesis by Promoting Lipid Synthesis and Depleting NADPH for Antioxidant Defenses

Cell reports (Cambridge), 2019-08, Vol.28 (9), p.2306-2316.e5

2019

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Liver-Specific Inhibition of ChREBP Improves Hepatic Steatosis and Insulin Resistance in ob/ob Mice

Diabetes (New York, N.Y.), 2006-08, Vol.55 (8), p.2159-2170

2006

Volltextzugriff (PDF)

Novel role for carbohydrate responsive element binding protein in the control of ethanol metabolism and susceptibility to binge drinking

Hepatology (Baltimore, Md.), 2015-10, Vol.62 (4), p.1086-1100

2015

Volltextzugriff (PDF)

Role of ChREBP in hepatic steatosis and insulin resistance

FEBS letters, 2008-01, Vol.582 (1), p.68-73

2008

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Adipocyte CREB Promotes Insulin Resistance in Obesity

Cell metabolism, 2009-03, Vol.9 (3), p.277-286

2009

Volltextzugriff (PDF)

UCP2 silencing restrains leukemia cell proliferation through glutamine metabolic remodeling

Frontiers in immunology, 2022-10, Vol.13, p.960226-960226

2022

Volltextzugriff (PDF)

Hepatic Glucokinase Is Required for the Synergistic Action of ChREBP and SREBP-1c on Glycolytic and Lipogenic Gene Expression

The Journal of biological chemistry, 2004-05, Vol.279 (19), p.20314-20326

2004

Volltextzugriff (PDF)

Cooperation Between the NRF2 Pathway and Oncogenic β‐catenin During HCC Tumorigenesis

Hepatology communications, 2021-09, Vol.5 (9), p.1490-1506

2021

Volltextzugriff (PDF)

Hepatic Gene Regulation by Glucose and Polyunsaturated Fatty Acids: A Role for ChREBP

The Journal of nutrition, 2006-05, Vol.136 (5), p.1145-1149

2006

Volltextzugriff (PDF)

ChREBPβ is dispensable for the control of glucose homeostasis and energy balance

JCI insight, 2022-02, Vol.7 (4)

2022

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Novel insights into ChREBP regulation and function

Trends in endocrinology and metabolism, 2013-05, Vol.24 (5), p.257-268

2013

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Integration of ChREBP-Mediated Glucose Sensing into Whole Body Metabolism

Physiology (Bethesda, Md.), 2015-11, Vol.30 (6), p.428-437

2015

Volltextzugriff (PDF)

Carbohydrate responsive element binding protein (ChREBP) and sterol regulatory element binding protein-1c (SREBP-1c): two key regulators of glucose metabolism and lipid synthesis in liver

Biochimie, 2005, Vol.87 (1), p.81-86

2005

Volltextzugriff (PDF)

Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2

Nature, 2007-09, Vol.449 (7160), p.366-369

2007

Volltextzugriff (PDF)

Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation

The Journal of clinical investigation, 2005-10, Vol.115 (10), p.2843-2854

2005

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Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice

A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange

Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in the liver

Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders

Hepatic Glucose Sensing via the CREB Coactivator CRTC2

The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity

The transcription factor ChREBP Orchestrates liver carcinogenesis by coordinating the PI3K/AKT signaling and cancer metabolism

O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver

A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response

ChREBP, a transcriptional regulator of glucose and lipid metabolism

UCP2 Deficiency Increases Colon Tumorigenesis by Promoting Lipid Synthesis and Depleting NADPH for Antioxidant Defenses

Liver-Specific Inhibition of ChREBP Improves Hepatic Steatosis and Insulin Resistance in ob/ob Mice

Novel role for carbohydrate responsive element binding protein in the control of ethanol metabolism and susceptibility to binge drinking

Role of ChREBP in hepatic steatosis and insulin resistance

Adipocyte CREB Promotes Insulin Resistance in Obesity

UCP2 silencing restrains leukemia cell proliferation through glutamine metabolic remodeling

Hepatic Glucokinase Is Required for the Synergistic Action of ChREBP and SREBP-1c on Glycolytic and Lipogenic Gene Expression

Cooperation Between the NRF2 Pathway and Oncogenic β‐catenin During HCC Tumorigenesis

Hepatic Gene Regulation by Glucose and Polyunsaturated Fatty Acids: A Role for ChREBP

ChREBPβ is dispensable for the control of glucose homeostasis and energy balance

Novel insights into ChREBP regulation and function

Integration of ChREBP-Mediated Glucose Sensing into Whole Body Metabolism

Carbohydrate responsive element binding protein (ChREBP) and sterol regulatory element binding protein-1c (SREBP-1c): two key regulators of glucose metabolism and lipid synthesis in liver

Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2

Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation

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