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Catalytic Asymmetric Diazoacetate Cyclopropanation of 1-Tosyl-3-vinylindoles. A Route to Conformationally Restricted Homotryptamines

Organic letters, 2005-06, Vol.7 (13), p.2651-2654

2005

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[18F](R)-5-chloro-1-(1-cyclopropyl-2-methoxyethyl)-3-(4-(2-fluoroethoxy)-2,5-dimethyl phenylamino)pyrazin-2(1H)-one: Introduction of N3-phenylpyrazinones as potential CRF-R1 PET imaging agents

Bioorganic & medicinal chemistry letters, 2012-11, Vol.22 (21), p.6651-6655

2012

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Conformationally Restricted Homotryptamines. 2. Indole Cyclopropylmethylamines as Selective Serotonin Reuptake Inhibitors

Journal of medicinal chemistry, 2005-09, Vol.48 (19), p.6023-6034

2005

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Synthesis of the Tricyclic Core of Sarain A. Use of Formaldehyde in an Intramolecular Grigg Azomethine Ylide Cyclization

Journal of organic chemistry, 1998-12, Vol.63 (26), p.9616-9617

1998

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In Vitro Intrinsic Clearance-Based Optimization of N 3-Phenylpyrazinones as Corticotropin-Releasing Factor-1 (CRF1) Receptor Antagonists

Journal of medicinal chemistry, 2009-07, Vol.52 (14), p.4161-4172

2009

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Potential CRF1R PET imaging agents: 1-Fluoroalkylsubstituted 5-halo-3-(arylamino)pyrazin-2(1H)-ones

Bioorganic & medicinal chemistry letters, 2013-04, Vol.23 (7), p.2052-2055

2013

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Conformationally restricted homotryptamines. Part 5: 3-(trans-2-aminomethylcyclopentyl)indoles as potent selective serotonin reuptake inhibitors

Bioorganic & medicinal chemistry letters, 2009-08, Vol.19 (15), p.4031-4033

2009

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Conformationally restricted homotryptamines. Part 4: Heterocyclic and naphthyl analogs of a potent selective serotonin reuptake inhibitor

Bioorganic & medicinal chemistry letters, 2007-10, Vol.17 (20), p.5647-5651

2007

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One-pot synthesis of homotryptamines from indoles

Tetrahedron letters, 2004-05, Vol.45 (19), p.3803-3805

2004

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Neurochemical, pharmacokinetic, and behavioral effects of the novel selective serotonin reuptake inhibitor BMS-505130

Pharmacology, biochemistry and behavior, 2005-03, Vol.80 (3), p.521-528

2005

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Homotryptamines as potent and selective serotonin reuptake inhibitors (SSRIs)

Bioorganic & medicinal chemistry letters, 2005-03, Vol.15 (6), p.1619-1621

2005

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Aminotriazine 5-HT7 antagonists

Bioorganic & medicinal chemistry letters, 2004-08, Vol.14 (16), p.4245-4248

2004

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Diaminopyrimidine and diaminopyridine 5-HT7 ligands

Bioorganic & medicinal chemistry letters, 2004-08, Vol.14 (16), p.4249-4252

2004

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Studies Related to the Carbohydrate Sectors of Esperamicin and Calicheamicin: Definition of the Stability Limits of the Esperamicin Domain and Fashioning of a Glycosyl Donor from the Calicheamicin Domain

Journal of the American Chemical Society, 1995-05, Vol.117 (21), p.5720-5749

1995

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Corrections to In Vitro Intrinsic Clearance-Based Optimization of N 3-Phenylpyrazinones as Corticotropin-Releasing Factor-1 (CRF1) Receptor Antagonists

Journal of medicinal chemistry, 2009-09, Vol.52 (18), p.5770-5770

2009

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In Vitro Intrinsic Clearance-Based Optimization of N3-Phenylpyrazinones as Corticotropin-Releasing Factor-1 (CRF1) Receptor Antagonists

Journal of medicinal chemistry, 2009-07, Vol.52 (14), p.4161-4172

2009

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Recent advances in the solid phase synthesis of drug-like heterocyclic small molecules

Combinatorial chemistry & high throughput screening, 1999-08, Vol.2 (4), p.191

1999

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Diaminopyrimidine and diaminopyridine 5-HT 7 ligands

Bioorganic & medicinal chemistry letters, 2004, Vol.14 (16), p.4249-4252

2004

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Aminotriazine 5-HT 7 antagonists

Bioorganic & medicinal chemistry letters, 2004, Vol.14 (16), p.4245-4248

2004

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Recent Advances in the Solid Phase Synthesis of Drug Heterocyclic Small Molecules

Combinatorial chemistry & high throughput screening, 1999-08, Vol.2 (4), p.191-210

1999

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Synthese und DNA-Bindungseigenschaften von Hybriden aus der Kohlenhydrat-Einheit von Calicheamicin γ1I und den Aglycon von Daunorubicin: Calichearubicine A und B

Angewandte Chemie, 1996-12, Vol.108 (23-24), p.2972-2975

1996

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Synthese und DNA‐Bindungseigenschaften von Hybriden aus der Kohlenhydrat‐Einheit von Calicheamicin γ 1 I und den Aglycon von Daunorubicin: Calichearubicine A und B

Angewandte Chemie, 1996-12, Vol.108 (23-24), p.2972-2975

1996

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A Strategy to Minimize Reactive Metabolite Formation: Discovery of (S)-4-(1-Cyclopropyl-2-methoxyethyl)-6-[6-(difluoromethoxy)-2,5-dimethylpyridin-3-ylamino]-5-oxo-4,5-dihydropyrazine-2-carbonitrile as a Potent, Orally Bioavailable Corticotropin-Releasing Factor-1 Receptor Antagonist

Catalytic Asymmetric Diazoacetate Cyclopropanation of 1-Tosyl-3-vinylindoles. A Route to Conformationally Restricted Homotryptamines

[18F](R)-5-chloro-1-(1-cyclopropyl-2-methoxyethyl)-3-(4-(2-fluoroethoxy)-2,5-dimethyl phenylamino)pyrazin-2(1H)-one: Introduction of N3-phenylpyrazinones as potential CRF-R1 PET imaging agents

Conformationally Restricted Homotryptamines. 2. Indole Cyclopropylmethylamines as Selective Serotonin Reuptake Inhibitors

Synthesis of the Tricyclic Core of Sarain A. Use of Formaldehyde in an Intramolecular Grigg Azomethine Ylide Cyclization

In Vitro Intrinsic Clearance-Based Optimization of N 3-Phenylpyrazinones as Corticotropin-Releasing Factor-1 (CRF1) Receptor Antagonists

Potential CRF1R PET imaging agents: 1-Fluoroalkylsubstituted 5-halo-3-(arylamino)pyrazin-2(1H)-ones

Synthesis, Structure−Activity Relationships, and In Vivo Evaluation of N 3-Phenylpyrazinones as Novel Corticotropin-Releasing Factor-1 (CRF1) Receptor Antagonists

Conformationally restricted homotryptamines. Part 5: 3-(trans-2-aminomethylcyclopentyl)indoles as potent selective serotonin reuptake inhibitors

Conformationally restricted homotryptamines. Part 4: Heterocyclic and naphthyl analogs of a potent selective serotonin reuptake inhibitor

One-pot synthesis of homotryptamines from indoles

Neurochemical, pharmacokinetic, and behavioral effects of the novel selective serotonin reuptake inhibitor BMS-505130

Homotryptamines as potent and selective serotonin reuptake inhibitors (SSRIs)

Aminotriazine 5-HT7 antagonists

Diaminopyrimidine and diaminopyridine 5-HT7 ligands

Studies Related to the Carbohydrate Sectors of Esperamicin and Calicheamicin: Definition of the Stability Limits of the Esperamicin Domain and Fashioning of a Glycosyl Donor from the Calicheamicin Domain

Corrections to In Vitro Intrinsic Clearance-Based Optimization of N 3-Phenylpyrazinones as Corticotropin-Releasing Factor-1 (CRF1) Receptor Antagonists

In Vitro Intrinsic Clearance-Based Optimization of N3-Phenylpyrazinones as Corticotropin-Releasing Factor-1 (CRF1) Receptor Antagonists

Synthesis, Structure—Activity Relationships, and In Vivo Evaluation of N3-Phenylpyrazinones as Novel Corticotropin-Releasing Factor-1 (CRF1) Receptor Antagonists

Recent advances in the solid phase synthesis of drug-like heterocyclic small molecules

Diaminopyrimidine and diaminopyridine 5-HT 7 ligands

Aminotriazine 5-HT 7 antagonists

Recent Advances in the Solid Phase Synthesis of Drug Heterocyclic Small Molecules

Synthese und DNA-Bindungseigenschaften von Hybriden aus der Kohlenhydrat-Einheit von Calicheamicin γ1I und den Aglycon von Daunorubicin: Calichearubicine A und B

Synthese und DNA‐Bindungseigenschaften von Hybriden aus der Kohlenhydrat‐Einheit von Calicheamicin γ 1 I und den Aglycon von Daunorubicin: Calichearubicine A und B

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