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Glutaminase is essential for the growth of triple-negative breast cancer cells with a deregulated glutamine metabolism pathway and its suppression synergizes with mTOR inhibition

PloS one, 2017-09, Vol.12 (9), p.e0185092-e0185092

2017

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Selective Inhibition of Mutant Isocitrate Dehydrogenase 1 (IDH1) via Disruption of a Metal Binding Network by an Allosteric Small Molecule

The Journal of biological chemistry, 2015-01, Vol.290 (2), p.762-774

2015

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Discovery of LFF571: An Investigational Agent for Clostridium difficile Infection

Journal of medicinal chemistry, 2012-03, Vol.55 (5), p.2376-2387

2012

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Applications of mass spectrometry in early stages of target based drug discovery

Journal of pharmaceutical and biomedical analysis, 2006-02, Vol.40 (3), p.528-538

2006

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Multiple cyclophilins involved in different cellular pathways mediate HCV replication

Virology (New York, N.Y.), 2010-02, Vol.397 (1), p.43-55

2010

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Biophysical Investigation of the Mode of Inhibition of Tetramic Acids, the Allosteric Inhibitors of Undecaprenyl Pyrophosphate Synthase

Biochemistry (Easton), 2010-06, Vol.49 (25), p.5366-5376

2010

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A trispecific antibody targeting HER2 and T cells inhibits breast cancer growth via CD4 cells

Nature (London), 2022-03, Vol.603 (7900), p.328-334

2022

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Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques

Science (American Association for the Advancement of Science), 2017-10, Vol.358 (6359), p.85-90

2017

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Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion

Cancer cell, 2015-12, Vol.28 (6), p.773-784

2015

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Amino acid sequence of a new type of antifreeze protein, from the longhorn sculpin Myoxocephalus octodecimspinosis

FEBS letters, 1997-02, Vol.402 (1), p.17-20

1997

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Abstract 1888: Anti-CD38 interference with blood compatibility testing: Differentiating isatuximab and daratumumab via functional epitope mapping

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1888-1888

2021

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Anti‐CD38 monoclonal antibody interference with blood compatibility testing: Differentiating isatuximab and daratumumab via functional epitope mapping

Transfusion (Philadelphia, Pa.), 2022-11, Vol.62 (11), p.2334-2348

2022

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Publisher Correction: A trispecific antibody targeting HER2 and T cells inhibits breast cancer growth via CD4 cells

Nature (London), 2022-04, Vol.604 (7905), p.E13-E13

2022

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Development of an LC–MS based enzyme activity assay for MurC: application to evaluation of inhibitors and kinetic analysis

Journal of pharmaceutical and biomedical analysis, 2004-06, Vol.35 (4), p.817-828

2004

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Abstract 5472: Basal-like breast cancer subtype is characterized by deregulated glutamine metabolism and is sensitive to GLS inhibition

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.5472-5472

2018

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Lys6-modified Ubiquitin Inhibits Ubiquitin-dependent Protein Degradation

The Journal of biological chemistry, 2005-05, Vol.280 (21), p.20365-20374

2005

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Ubiquitin-activating Enzyme (E1) Isoforms in Lens Epithelial Cells: Origin of Translation, E2 Specificity and Cellular Localization Determined with Novel Site-specific Antibodies

Experimental eye research, 2001-12, Vol.73 (6), p.827-836

2001

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Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches

The Journal of biological chemistry, 2013-10, Vol.288 (42), p.30125-30138

2013

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Real-time analysis of antibody interactions with whole enveloped human cytomegalovirus using surface plasmon resonance

Analytical biochemistry, 2011-04, Vol.411 (1), p.58-63

2011

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Applications of mass spectrometry in early stages of target based drug discovery: Hyphenated techniques in pharmaceutical and biomedical analysis

Journal of pharmaceutical and biomedical analysis, 2006, Vol.40 (3), p.528-538

2006

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Isolation and characterization of an antifreeze protein from the longhorn sculpin, Myoxocephalus octodecimspinosis

Biochimica et biophysica acta, 1998-11, Vol.1388 (2), p.305-314

1998

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A Robust Multiplex Mass Spectrometric Assay for Screening Small-Molecule Inhibitors of CD73 with Diverse Inhibition Modalities

SLAS discovery, 2018-03, Vol.23 (3), p.264-273

2018

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Abstract 4746: Selective inhibition of mutant IDH1 via small molecule binding to the dimer interface

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.4746-4746

2014

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Glutaminase is essential for the growth of triple-negative breast cancer cells with a deregulated glutamine metabolism pathway and its suppression synergizes with mTOR inhibition

Selective Inhibition of Mutant Isocitrate Dehydrogenase 1 (IDH1) via Disruption of a Metal Binding Network by an Allosteric Small Molecule

Discovery of LFF571: An Investigational Agent for Clostridium difficile Infection

Applications of mass spectrometry in early stages of target based drug discovery

Multiple cyclophilins involved in different cellular pathways mediate HCV replication

Biophysical Investigation of the Mode of Inhibition of Tetramic Acids, the Allosteric Inhibitors of Undecaprenyl Pyrophosphate Synthase

A trispecific antibody targeting HER2 and T cells inhibits breast cancer growth via CD4 cells

Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques

Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion

Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation

Amino acid sequence of a new type of antifreeze protein, from the longhorn sculpin Myoxocephalus octodecimspinosis

Abstract 1888: Anti-CD38 interference with blood compatibility testing: Differentiating isatuximab and daratumumab via functional epitope mapping

Anti‐CD38 monoclonal antibody interference with blood compatibility testing: Differentiating isatuximab and daratumumab via functional epitope mapping

Publisher Correction: A trispecific antibody targeting HER2 and T cells inhibits breast cancer growth via CD4 cells

Development of an LC–MS based enzyme activity assay for MurC: application to evaluation of inhibitors and kinetic analysis

Abstract 5472: Basal-like breast cancer subtype is characterized by deregulated glutamine metabolism and is sensitive to GLS inhibition

Lys6-modified Ubiquitin Inhibits Ubiquitin-dependent Protein Degradation

Ubiquitin-activating Enzyme (E1) Isoforms in Lens Epithelial Cells: Origin of Translation, E2 Specificity and Cellular Localization Determined with Novel Site-specific Antibodies

Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches

Identification of elongation factor G as the conserved cellular target of argyrin B

Real-time analysis of antibody interactions with whole enveloped human cytomegalovirus using surface plasmon resonance

Applications of mass spectrometry in early stages of target based drug discovery: Hyphenated techniques in pharmaceutical and biomedical analysis

Isolation and characterization of an antifreeze protein from the longhorn sculpin, Myoxocephalus octodecimspinosis

A Robust Multiplex Mass Spectrometric Assay for Screening Small-Molecule Inhibitors of CD73 with Diverse Inhibition Modalities

Abstract 4746: Selective inhibition of mutant IDH1 via small molecule binding to the dimer interface

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