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Cell-Penetrating Peptides: Design, Development and Applications

1, 2022

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Critical role of mitochondrial ubiquitination and the OPTN-ATG9A axis in mitophagy

The Journal of cell biology, 2020-09, Vol.219 (9), p.1

2020

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Helical Antimicrobial Peptide Foldamers Containing Non‐proteinogenic Amino Acids

ChemMedChem, 2021-04, Vol.16 (8), p.1226-1233

2021

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N-Nitrosodimethylamine (NDMA) Formation from Ranitidine Impurities: Possible Root Causes of the Presence of NDMA in Ranitidine Hydrochloride

Chemical and Pharmaceutical Bulletin, 2021/09/01, Vol.69(9), pp.872-876

2021

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Fcγ Receptor-Dependent Internalization and Off-Target Cytotoxicity of Antibody-Drug Conjugate Aggregates

Pharmaceutical research, 2022-01, Vol.39 (1), p.89-103

2022

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Design and synthesis of peptide-based chimeric molecules to induce degradation of the estrogen and androgen receptors

Bioorganic & medicinal chemistry, 2020-08, Vol.28 (15), p.115595-115595, Article 115595

2020

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Recent Advances in PROTAC Technology Toward New Therapeutic Modalities

Chemistry & biodiversity, 2022-11, Vol.19 (11), p.e202200828-n/a

2022

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Development of Antimicrobial Stapled Peptides Based on Magainin 2 Sequence

Molecules (Basel, Switzerland), 2021-01, Vol.26 (2), p.444

2021

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Development of BCR-ABL degradation inducers via the conjugation of an imatinib derivative and a cIAP1 ligand

Bioorganic & medicinal chemistry letters, 2016-10, Vol.26 (20), p.4865-4869

2016

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Development of Photoswitchable Estrogen Receptor Ligands

Chemical and Pharmaceutical Bulletin, 2020/04/01, Vol.68(4), pp.398-402

2020

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Derivatives of methoxetamine and major methoxetamine metabolites potently block NMDA receptors

Journal of pharmacological sciences, 2022-12, Vol.150 (4), p.233-243

2022

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Facile Synthesis of Kwakhurin, a Marker Compound of Pueraria mirifica and Its Quantitative NMR Analysis for Standardization as a Reagent

Chemical and Pharmaceutical Bulletin, 2020/08/01, Vol.68(8), pp.797-801

2020

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Control of STING Agonistic/Antagonistic Activity Using Amine-Skeleton-Based c-di-GMP Analogues

International journal of molecular sciences, 2022-06, Vol.23 (12), p.6847

2022

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Development of 2-aminoisobutyric acid (Aib)-rich cell-penetrating foldamers for efficient siRNA delivery

Chemical communications (Cambridge, England), 2019-07, Vol.55 (54), p.7792-7795

2019

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Deubiquitylase USP25 prevents degradation of BCR-ABL protein and ensures proliferation of Ph-positive leukemia cells

Oncogene, 2020-05, Vol.39 (19), p.3867-3878

2020

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Selective Degradation of Target Proteins by Chimeric Small-Molecular Drugs, PROTACs and SNIPERs

Pharmaceuticals (Basel, Switzerland), 2020-04, Vol.13 (4), p.74

2020

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The effects of magainin 2-derived and rationally designed antimicrobial peptides on Mycoplasma pneumoniae

PloS one, 2022-01, Vol.17 (1), p.e0261893-e0261893

2022

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Development of Hydrophobic Cell-Penetrating Stapled Peptides as Drug Carriers

International journal of molecular sciences, 2023-07, Vol.24 (14), p.11768

2023

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Development of hybrid small molecules that induce degradation of estrogen receptor‐alpha and necrotic cell death in breast cancer cells

Cancer science, 2013-11, Vol.104 (11), p.1492-1498

2013

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Structure–activity relationship study of amphipathic antimicrobial peptides using helix‐destabilizing sarcosine

Journal of peptide science, 2021-12, Vol.27 (12), p.e3360-n/a

2021

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Rapid Structure Determination of Ranitidine Hydrochloride API in Two Crystal Forms Using Microcrystal Electron Diffraction

Chemical & pharmaceutical bulletin, 2024, Vol.72 (5), p.471-474, Article c23-00745

2024

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Copper‐Catalyzed Enantioselective Synthesis of Oxazolines from Aminotriols via Asymmetric Desymmetrization

Chemistry, an Asian journal, 2020-03, Vol.15 (6), p.840-844

2020

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Antiviral activity of ciclesonide acetal derivatives blocking SARS-CoV-2 RNA replication

Journal of pharmacological sciences, 2022-07, Vol.149 (3), p.81-84

2022

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Analysis of an Impurity, N-Nitrosodimethylamine, in Valsartan Drug Substances and Associated Products Using GC-MS

Biological and Pharmaceutical Bulletin, 2019/04/01, Vol.42(4), pp.547-551

2019

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Rational Design and Synthesis of Post-Functionalizable Peptide Foldamers as Helical Templates

Bioconjugate chemistry, 2017-12, Vol.28 (12), p.3029-3035

2017

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Cell-Penetrating Peptides: Design, Development and Applications

Critical role of mitochondrial ubiquitination and the OPTN-ATG9A axis in mitophagy

Helical Antimicrobial Peptide Foldamers Containing Non‐proteinogenic Amino Acids

N-Nitrosodimethylamine (NDMA) Formation from Ranitidine Impurities: Possible Root Causes of the Presence of NDMA in Ranitidine Hydrochloride

Fcγ Receptor-Dependent Internalization and Off-Target Cytotoxicity of Antibody-Drug Conjugate Aggregates

Design and synthesis of peptide-based chimeric molecules to induce degradation of the estrogen and androgen receptors

Recent Advances in PROTAC Technology Toward New Therapeutic Modalities

Development of Antimicrobial Stapled Peptides Based on Magainin 2 Sequence

Development of BCR-ABL degradation inducers via the conjugation of an imatinib derivative and a cIAP1 ligand

Development of Photoswitchable Estrogen Receptor Ligands

Derivatives of methoxetamine and major methoxetamine metabolites potently block NMDA receptors

Facile Synthesis of Kwakhurin, a Marker Compound of Pueraria mirifica and Its Quantitative NMR Analysis for Standardization as a Reagent

Control of STING Agonistic/Antagonistic Activity Using Amine-Skeleton-Based c-di-GMP Analogues

Development of 2-aminoisobutyric acid (Aib)-rich cell-penetrating foldamers for efficient siRNA delivery

Deubiquitylase USP25 prevents degradation of BCR-ABL protein and ensures proliferation of Ph-positive leukemia cells

Selective Degradation of Target Proteins by Chimeric Small-Molecular Drugs, PROTACs and SNIPERs

The effects of magainin 2-derived and rationally designed antimicrobial peptides on Mycoplasma pneumoniae

Development of Hydrophobic Cell-Penetrating Stapled Peptides as Drug Carriers

Development of hybrid small molecules that induce degradation of estrogen receptor‐alpha and necrotic cell death in breast cancer cells

Structure–activity relationship study of amphipathic antimicrobial peptides using helix‐destabilizing sarcosine

Rapid Structure Determination of Ranitidine Hydrochloride API in Two Crystal Forms Using Microcrystal Electron Diffraction

Copper‐Catalyzed Enantioselective Synthesis of Oxazolines from Aminotriols via Asymmetric Desymmetrization

Antiviral activity of ciclesonide acetal derivatives blocking SARS-CoV-2 RNA replication

Analysis of an Impurity, N-Nitrosodimethylamine, in Valsartan Drug Substances and Associated Products Using GC-MS

Rational Design and Synthesis of Post-Functionalizable Peptide Foldamers as Helical Templates

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