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Discovery of a novel aminopyrazine series as selective PI3Kα inhibitors

Bioorganic & medicinal chemistry letters, 2017-07, Vol.27 (13), p.3030-3035

2017

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Design of selective PI3Kα inhibitors starting from a promiscuous pan kinase scaffold

Bioorganic & medicinal chemistry letters, 2015-07, Vol.25 (13), p.2679-2685

2015

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Facile preparation and Suzuki–Miyaura cross-coupling of N-2-alkylated 2H-1,2,3-triazole 4-boronates

Tetrahedron letters, 2012-12, Vol.53 (50), p.6849-6852

2012

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Discovery and application of iminotriphenylphosphorane as a formal aromatic primary amine protecting group

Tetrahedron letters, 2012-10, Vol.53 (40), p.5380-5384

2012

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Synthetic studies toward cytostatin, a natural product inhibitor of protein phosphatase 2A

Tetrahedron, 2008-07, Vol.64 (28), p.6684-6697

2008

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Facile, diversity-orientated one-pot synthesis of ethyl 1,5-disubstituted-1H-1,2,4-triazole-3-carboxylates

Tetrahedron letters, 2012-11, Vol.53 (45), p.6078-6082

2012

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Structure–activity relationship of a series of non peptidic RGD integrin antagonists targeting α5β1: Part 2

Bioorganic & medicinal chemistry letters, 2012-06, Vol.22 (12), p.4117-4121

2012

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Synthesis and structure–activity relationships of thieno[2,3- b]pyrroles as antagonists of the GnRH receptor

Bioorganic & medicinal chemistry, 2007-12, Vol.17 (23), p.6448-6454

2007

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Novel 4-anilinoquinazolines with C-6 carbon-linked side chains: Synthesis and structure–activity relationship of a series of potent, orally active, EGF receptor tyrosine kinase inhibitors

Bioorganic & medicinal chemistry letters, 2006-05, Vol.16 (10), p.2672-2676

2006

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New Advances in Bis(Sulfoxides) Chemistry

Phosphorus, sulfur, and silicon and the related elements, 2013-04, Vol.188 (4), p.367-376

2013

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Conjugate Additions to Alkylidene Bis(Sulfoxides)

Chemistry, an Asian journal, 2011-07, Vol.6 (7), p.1825-1833

2011

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Abstract 2830: Discovery of AZD8835, a potent and selective inhibitor of PI3Kα and PI3Kδ for the treatment of PIK3CA -dependent cancers

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.2830-2830

2015

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Structure–activity relationship of a series of non peptidic RGD integrin antagonists targeting α5β1: Part 1

Bioorganic & medicinal chemistry letters, 2012-06, Vol.22 (12), p.4111-4116

2012

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Structureaactivity relationship of a series of non peptidic RGD integrin antagonists targeting I-5I21: Part 1

Bioorganic & medicinal chemistry letters, 2012-06, Vol.22 (12), p.4111-4116

2012

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Structureaactivity relationship of a series of non peptidic RGD integrin antagonists targeting I-5I21: Part 2

Bioorganic & medicinal chemistry letters, 2012-06, Vol.22 (12), p.4117-4121

2012

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Fischer synthesis of isomeric thienopyrrole LHRH antagonists

Tetrahedron, 2009-07, Vol.65 (29), p.5805-5816

2009

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Recent Developments in the Construction of trans-Fused Polycyclic Ethers

ChemInform, 2003-06, Vol.34 (24), p.no-no

2003

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ChemInform Abstract: Discovery and Application of Iminotriphenylphosphorane as a Formal Aromatic Primary Amine Protecting Group

ChemInform, 2013-01, Vol.44 (3), p.no-no

2013

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Highly Diastereoselective Conjugate Addition to Alkylidene Bis(Sulfoxides): Asymmetric Synthesis of (+)-erythro-Roccellic Acid

Angewandte Chemie International Edition, 2003-11, Vol.42 (43), p.5342-5345

2003

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ChemInform Abstract: Facile Preparation and Suzuki-Miyaura Cross-Coupling of N-2-Alkylated 2H-1,2,3-Triazole 4-Boronates

ChemInform, 2013-04, Vol.44 (14), p.no-no

2013

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ChemInform Abstract: Facile, Diversity-Orientated One-Pot Synthesis of Ethyl 1,5-Disubstituted-1H-1,2,4-triazole-3-carboxylates

ChemInform, 2013-02, Vol.44 (7), p.no-no

2013

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Asymmetric Intramolecular Radical Vinylation Using Enantiopure Sulfoxides as Temporary Chiral Auxiliaries

Journal of the American Chemical Society, 1999-12, Vol.121 (49), p.11395-11401

1999

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The Chemistry of C2-Symmetric Bis(sulfoxides): A New Approach in Asymmetric Synthesis

European journal of organic chemistry, 2002-11, Vol.2002 (21), p.3507-3525

2002

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Addition of Bis-sulfinyl Anions to Ketones: Stereoselective Synthesis of Allylic Alcohols Through Evans-Mislow Rearrangement Based Domino Reactions

ChemInform, 2007-12, Vol.38 (51), p.no-no

2007

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Discovery of a novel aminopyrazine series as selective PI3Kα inhibitors

Design of selective PI3Kα inhibitors starting from a promiscuous pan kinase scaffold

Facile preparation and Suzuki–Miyaura cross-coupling of N-2-alkylated 2H-1,2,3-triazole 4-boronates

Discovery and application of iminotriphenylphosphorane as a formal aromatic primary amine protecting group

Synthetic studies toward cytostatin, a natural product inhibitor of protein phosphatase 2A

Facile, diversity-orientated one-pot synthesis of ethyl 1,5-disubstituted-1H-1,2,4-triazole-3-carboxylates

Structure–activity relationship of a series of non peptidic RGD integrin antagonists targeting α5β1: Part 2

Synthesis and structure–activity relationships of thieno[2,3- b]pyrroles as antagonists of the GnRH receptor

Novel 4-anilinoquinazolines with C-6 carbon-linked side chains: Synthesis and structure–activity relationship of a series of potent, orally active, EGF receptor tyrosine kinase inhibitors

New Advances in Bis(Sulfoxides) Chemistry

Conjugate Additions to Alkylidene Bis(Sulfoxides)

Abstract 2830: Discovery of AZD8835, a potent and selective inhibitor of PI3Kα and PI3Kδ for the treatment of PIK3CA -dependent cancers

Structure–activity relationship of a series of non peptidic RGD integrin antagonists targeting α5β1: Part 1

Structureaactivity relationship of a series of non peptidic RGD integrin antagonists targeting I-5I21: Part 1

Structureaactivity relationship of a series of non peptidic RGD integrin antagonists targeting I-5I21: Part 2

Fischer synthesis of isomeric thienopyrrole LHRH antagonists

Discovery of 1-(4-(5-(5-amino-6-(5-tert-butyl-1,3,4-oxadiazol-2-yl)pyrazin-2-yl)-1-ethyl-1,2,4-triazol-3-yl)piperidin-1-yl)-3-hydroxypropan-1-one (AZD8835): A potent and selective inhibitor of PI3Kα and PI3Kδ for the treatment of cancers

Recent Developments in the Construction of trans-Fused Polycyclic Ethers

ChemInform Abstract: Discovery and Application of Iminotriphenylphosphorane as a Formal Aromatic Primary Amine Protecting Group

Highly Diastereoselective Conjugate Addition to Alkylidene Bis(Sulfoxides): Asymmetric Synthesis of (+)-erythro-Roccellic Acid

ChemInform Abstract: Facile Preparation and Suzuki-Miyaura Cross-Coupling of N-2-Alkylated 2H-1,2,3-Triazole 4-Boronates

ChemInform Abstract: Facile, Diversity-Orientated One-Pot Synthesis of Ethyl 1,5-Disubstituted-1H-1,2,4-triazole-3-carboxylates

Asymmetric Intramolecular Radical Vinylation Using Enantiopure Sulfoxides as Temporary Chiral Auxiliaries

The Chemistry of C2-Symmetric Bis(sulfoxides): A New Approach in Asymmetric Synthesis

Addition of Bis-sulfinyl Anions to Ketones: Stereoselective Synthesis of Allylic Alcohols Through Evans-Mislow Rearrangement Based Domino Reactions

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