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Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

Nature communications, 2016-10, Vol.7 (1), p.12948-14, Article 12948

2016

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Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle

Cell metabolism, 2016-08, Vol.24 (2), p.269-282

2016

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Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double-blind, placebo-controlled clinical trial

Hepatology (Baltimore, Md.), 2023-09, Vol.78 (3), p.863-877

2023

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Defining NAD(P)(H) Catabolism

Nutrients, 2023-07, Vol.15 (13), p.3064

2023

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Nicotinamide adenine dinucleotide biosynthesis promotes liver regeneration

Hepatology (Baltimore, Md.), 2017-02, Vol.65 (2), p.616-630

2017

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Pterostilbene in Cancer Therapy

Antioxidants, 2021-03, Vol.10 (3), p.492

2021

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Differences in the Glucuronidation of Resveratrol and Pterostilbene: Altered Enzyme Specificity and Potential Gender Differences

DRUG METABOLISM AND PHARMACOKINETICS, 2014, Vol.29 (2), p.112-119

2014

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Efficacy and tolerability of EH301 for amyotrophic lateral sclerosis: a randomized, double-blind, placebo-controlled human pilot study

Amyotrophic lateral sclerosis and frontotemporal degeneration, 2019-01, Vol.20 (1-2), p.115-122

2019

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Combination of natural polyphenols with a precursor of NAD+ and a TLR2/6 ligand lipopeptide protects mice against lethal γ radiation

Journal of advanced research, 2023-03, Vol.45, p.73-86

2023

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A randomized placebo-controlled trial of nicotinamide riboside and pterostilbene supplementation in experimental muscle injury in elderly individuals

JCI insight, 2022-10, Vol.7 (19)

2022

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Intravenous nicotinamide riboside elevates mouse skeletal muscle NAD+ without impacting respiratory capacity or insulin sensitivity

iScience, 2022-02, Vol.25 (2), p.103863-103863, Article 103863

2022

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NAD + Precursors and Antioxidants for the Treatment of Amyotrophic Lateral Sclerosis

Biomedicines, 2021-08, Vol.9 (8), p.1000

2021

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Anti-cancer drugs elicit re-expression of UDP-glucuronosyltransferases in melanoma cells

PloS one, 2012-10, Vol.7 (10), p.e47696

2012

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Oxidative stress and antioxidants in the pathophysiology of malignant melanoma

Biological chemistry, 2019-04, Vol.400 (5), p.589-612

2019

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Polyphenolic Phytochemicals in Cancer Prevention and Therapy: Bioavailability versus Bioefficacy

Journal of medicinal chemistry, 2017-12, Vol.60 (23), p.9413-9436

2017

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Glucuronidation of active tamoxifen metabolites by the human UDP glucuronosyltransferases

Drug metabolism and disposition, 2007-11, Vol.35 (11), p.2006-2014

2007

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Glucuronidation of tobacco-specific nitrosamines by UGT2B10

Drug metabolism and disposition, 2008-05, Vol.36 (5), p.824-830

2008

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Characterization of tamoxifen and 4-hydroxytamoxifen glucuronidation by human UGT1A4 variants

Breast cancer research : BCR, 2006-01, Vol.8 (4), p.R50-R50, Article R50

2006

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Gene expression profiles in sporadic ALS fibroblasts define disease subtypes and the metabolic effects of the investigational drug EH301

Human molecular genetics, 2022-10, Vol.31 (20), p.3458-3477

2022

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Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD+ levels in humans safely and sustainably: a randomized, double-blind, placebo-controlled study

npj aging and mechanisms of disease, 2017-11, Vol.3 (1), p.17-9, Article 17

2017

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Nicotinamide riboside, pterostilbene and ibudilast protect motor neurons and extend survival in ALS mice

Neurotherapeutics, 2024-01, Vol.21 (1), p.e00301-e00301, Article e00301

2024

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Functional characterization of low-prevalence missense polymorphisms in the UDP-glucuronosyltransferase 1A9 gene

Drug metabolism and disposition, 2009-10, Vol.37 (10), p.1999-2007

2009

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Elevated homocysteine is associated with increased rates of epigenetic aging in a population with mild cognitive impairment

Aging cell, 2024-10, Vol.23 (10), p.e14255-n/a

2024

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Inhibition of UVB radiation‐induced tissue swelling and immune suppression by nicotinamide riboside and pterostilbene

Photodermatology, photoimmunology & photomedicine, 2024-05, Vol.40 (3), p.e12961-n/a

2024

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Safety Assessment of High-Purity, Synthetic Nicotinamide Riboside (NR-E) in a 90-Day Repeated Dose Oral Toxicity Study, With a 28-Day Recovery Arm

International journal of toxicology, 2020-07, Vol.39 (4), p.307-320

2020

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Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle

Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double-blind, placebo-controlled clinical trial

Defining NAD(P)(H) Catabolism

Nicotinamide adenine dinucleotide biosynthesis promotes liver regeneration

Pterostilbene in Cancer Therapy

Differences in the Glucuronidation of Resveratrol and Pterostilbene: Altered Enzyme Specificity and Potential Gender Differences

Efficacy and tolerability of EH301 for amyotrophic lateral sclerosis: a randomized, double-blind, placebo-controlled human pilot study

Combination of natural polyphenols with a precursor of NAD+ and a TLR2/6 ligand lipopeptide protects mice against lethal γ radiation

A randomized placebo-controlled trial of nicotinamide riboside and pterostilbene supplementation in experimental muscle injury in elderly individuals

Intravenous nicotinamide riboside elevates mouse skeletal muscle NAD+ without impacting respiratory capacity or insulin sensitivity

NAD + Precursors and Antioxidants for the Treatment of Amyotrophic Lateral Sclerosis

Anti-cancer drugs elicit re-expression of UDP-glucuronosyltransferases in melanoma cells

Oxidative stress and antioxidants in the pathophysiology of malignant melanoma

Polyphenolic Phytochemicals in Cancer Prevention and Therapy: Bioavailability versus Bioefficacy

Glucuronidation of active tamoxifen metabolites by the human UDP glucuronosyltransferases

Glucuronidation of tobacco-specific nitrosamines by UGT2B10

Characterization of tamoxifen and 4-hydroxytamoxifen glucuronidation by human UGT1A4 variants

Gene expression profiles in sporadic ALS fibroblasts define disease subtypes and the metabolic effects of the investigational drug EH301

Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD+ levels in humans safely and sustainably: a randomized, double-blind, placebo-controlled study

Nicotinamide riboside, pterostilbene and ibudilast protect motor neurons and extend survival in ALS mice

Functional characterization of low-prevalence missense polymorphisms in the UDP-glucuronosyltransferase 1A9 gene

Elevated homocysteine is associated with increased rates of epigenetic aging in a population with mild cognitive impairment

Inhibition of UVB radiation‐induced tissue swelling and immune suppression by nicotinamide riboside and pterostilbene

Safety Assessment of High-Purity, Synthetic Nicotinamide Riboside (NR-E) in a 90-Day Repeated Dose Oral Toxicity Study, With a 28-Day Recovery Arm

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