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Precision genome editing in the CRISPR era

Biochemistry and cell biology, 2017-04, Vol.95 (2), p.187-201

2017

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Nuclear domain 'knock-in' screen for the evaluation and identification of small molecule enhancers of CRISPR-based genome editing

Nucleic acids research, 2015-10, Vol.43 (19), p.9379-9392

2015

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A mechanism for the suppression of homologous recombination in G1 cells

Nature (London), 2015-12, Vol.528 (7582), p.422-426

2015

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Marker-free coselection for CRISPR-driven genome editing in human cells

Nature methods, 2017-06, Vol.14 (6), p.615-620

2017

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Coupling of Homologous Recombination and the Checkpoint by ATR

Molecular cell, 2017-01, Vol.65 (2), p.336-346

2017

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Back to Basics: Application of the Principles of Bioethics to Heritable Genome Interventions

Science and engineering ethics, 2020-10, Vol.26 (5), p.2735-2748

2020

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Hooking the big one: the potential of zebrafish xenotransplantation to reform cancer drug screening in the genomic era

Disease models & mechanisms, 2014-07, Vol.7 (7), p.745-754

2014

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A RAD51 assay feasible in routine tumor samples calls PARP inhibitor response beyond BRCA mutation

EMBO molecular medicine, 2018-12, Vol.10 (12), p.1-n/a

2018

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Nuclear position dictates DNA repair pathway choice

Genes & development, 2014-11, Vol.28 (22), p.2450-2463

2014

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Nuclear lipid droplets in Caco2 cells originate from nascent precursors and in situ at the nuclear envelope

Journal of lipid research, 2024-05, Vol.65 (5), p.100540-100540, Article 100540

2024

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Dominant negative Gfi1b mutations cause moderate thrombocytopenia and an impaired stress thrombopoiesis associated with mild erythropoietic abnormalities in mice

Haematologica (Roma), 2020-10, Vol.105 (10), p.2457-2470

2020

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Zebrafish xenografts as a tool for in vivo studies on human cancer

Annals of the New York Academy of Sciences, 2012-08, Vol.1266 (1), p.124-137

2012

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Microbial eukaryotes have adapted to hypoxia by horizontal acquisitions of a gene involved in rhodoquinone biosynthesis

eLife, 2018-04, Vol.7

2018

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Regulation of Nrf2/ARE Pathway by Dietary Flavonoids: A Friend or Foe for Cancer Management?

Antioxidants, 2020-10, Vol.9 (10), p.973

2020

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PML nuclear bodies: dynamic sensors of DNA damage and cellular stress

BioEssays, 2004-09, Vol.26 (9), p.963-977

2004

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Bitter taste receptors are expressed in human epithelial ovarian and prostate cancers cells and noscapine stimulation impacts cell survival

Molecular and cellular biochemistry, 2019-04, Vol.454 (1-2), p.203-214

2019

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Tinker, Tailor, Tumour Suppressor: The Many Functions of PRP4K

Frontiers in genetics, 2022-02, Vol.13, p.839963-839963

2022

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Genistein and Procyanidin B2 Reduce Carcinogen-Induced Reactive Oxygen Species and DNA Damage through the Activation of Nrf2/ARE Cell Signaling in Bronchial Epithelial Cells In Vitro

International journal of molecular sciences, 2023-02, Vol.24 (4), p.3676

2023

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Focused chemical genomics using zebrafish xenotransplantation as a pre-clinical therapeutic platform for T-cell acute lymphoblastic leukemia

Haematologica (Roma), 2015-01, Vol.100 (1), p.70-76

2015

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Humanized zebrafish enhance human hematopoietic stem cell survival and promote acute myeloid leukemia clonal diversity

Haematologica (Roma), 2020-10, Vol.105 (10), p.2391-2399

2020

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The Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and Repair

Biomolecules (Basel, Switzerland), 2015-09, Vol.5 (4), p.2388-2416

2015

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GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1

Nature communications, 2018-04, Vol.9 (1), p.1418-14, Article 1418

2018

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Novel RNA and DNA strand exchange activity of the PALB2 DNA binding domain and its critical role for DNA repair in cells

eLife, 2019-04, Vol.8

2019

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NPM and NPM-MLF1 interact with chromatin remodeling complexes and influence their recruitment to specific genes

PLoS genetics, 2019-11, Vol.15 (11), p.e1008463-e1008463

2019

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Changes in Chromatin Structure and Mobility in Living Cells at Sites of DNA Double-Strand Breaks

The Journal of cell biology, 2006-03, Vol.172 (6), p.823-834

2006

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Precision genome editing in the CRISPR era

Nuclear domain 'knock-in' screen for the evaluation and identification of small molecule enhancers of CRISPR-based genome editing

A mechanism for the suppression of homologous recombination in G1 cells

Marker-free coselection for CRISPR-driven genome editing in human cells

Coupling of Homologous Recombination and the Checkpoint by ATR

Back to Basics: Application of the Principles of Bioethics to Heritable Genome Interventions

Hooking the big one: the potential of zebrafish xenotransplantation to reform cancer drug screening in the genomic era

A RAD51 assay feasible in routine tumor samples calls PARP inhibitor response beyond BRCA mutation

Nuclear position dictates DNA repair pathway choice

Nuclear lipid droplets in Caco2 cells originate from nascent precursors and in situ at the nuclear envelope

Dominant negative Gfi1b mutations cause moderate thrombocytopenia and an impaired stress thrombopoiesis associated with mild erythropoietic abnormalities in mice

Zebrafish xenografts as a tool for in vivo studies on human cancer

Microbial eukaryotes have adapted to hypoxia by horizontal acquisitions of a gene involved in rhodoquinone biosynthesis

Regulation of Nrf2/ARE Pathway by Dietary Flavonoids: A Friend or Foe for Cancer Management?

PML nuclear bodies: dynamic sensors of DNA damage and cellular stress

Bitter taste receptors are expressed in human epithelial ovarian and prostate cancers cells and noscapine stimulation impacts cell survival

Tinker, Tailor, Tumour Suppressor: The Many Functions of PRP4K

Genistein and Procyanidin B2 Reduce Carcinogen-Induced Reactive Oxygen Species and DNA Damage through the Activation of Nrf2/ARE Cell Signaling in Bronchial Epithelial Cells In Vitro

Focused chemical genomics using zebrafish xenotransplantation as a pre-clinical therapeutic platform for T-cell acute lymphoblastic leukemia

Humanized zebrafish enhance human hematopoietic stem cell survival and promote acute myeloid leukemia clonal diversity

The Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and Repair

GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1

Novel RNA and DNA strand exchange activity of the PALB2 DNA binding domain and its critical role for DNA repair in cells

NPM and NPM-MLF1 interact with chromatin remodeling complexes and influence their recruitment to specific genes

Changes in Chromatin Structure and Mobility in Living Cells at Sites of DNA Double-Strand Breaks

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