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In vitro and in vivo biochemistry of olanzapine: a novel, atypical antipsychotic drug

The journal of clinical psychiatry, 1997, Vol.58 Suppl 10, p.28

1997

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Intrathecal pertussis toxin produces hyperalgesia and allodynia in mice

Pain (Amsterdam), 1997-04, Vol.70 (2), p.223-228

1997

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The minimum significant ratio: a statistical parameter to characterize the reproducibility of potency estimates from concentration-response assays and estimation by replicate-experiment studies

Journal of biomolecular screening, 2006-04, Vol.11 (3), p.253-261

2006

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Muscarinic receptor agonists decrease cocaine self-administration rates in drug-naive mice

European journal of pharmacology, 2000-08, Vol.402 (3), p.241-246

2000

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Unexpected antipsychotic-like activity with the muscarinic receptor ligand (5 R,6 R)6-(3-propylthio-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane

European journal of pharmacology, 1998-09, Vol.356 (2), p.109-119

1998

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M1 muscarinic receptor signaling in mouse hippocampus and cortex

Brain research, 2002-07, Vol.944 (1), p.82-89

2002

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Muscarinic Agonists with Antipsychotic-like Activity: Structure−Activity Relationships of 1,2,5-Thiadiazole Analogues with Functional Dopamine Antagonist Activity

Journal of medicinal chemistry, 1998-10, Vol.41 (22), p.4378-4384

1998

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Determination of [35S]guanosine-5'-O-(3-thio)triphosphate binding mediated by cholinergic muscarinic receptors in membranes from Chinese hamster ovary cells and rat striatum using an anti-G protein scintillation proximity assay

The Journal of pharmacology and experimental therapeutics, 1999-05, Vol.289 (2), p.946

1999

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Muscarinic agonists exhibit functional dopamine antagonism in unilaterally 6-OHDA lesioned rats

Neuroreport, 1998-10, Vol.9 (15), p.3481-3486

1998

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Forskolin Stimulation of Cyclic AMP Accumulation in Rat Brain Cortex Slices Is Markedly Enhanced by Endogenous Adenosine

Journal of neurochemistry, 1992-01, Vol.58 (1), p.237-242

1992

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Identification of side chains on 1,2,5-thiadiazole-azacycles optimal for muscarinic M1 receptor activation

Bioorganic & medicinal chemistry letters, 1998-10, Vol.8 (20), p.2897-2902

1998

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Muscarinic receptor agonists, like dopamine receptor antagonist antipsychotics, inhibit conditioned avoidance response in rats

The Journal of pharmacology and experimental therapeutics, 1999-08, Vol.290 (2), p.901

1999

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The muscarinic receptor agonist BuTAC, a novel potential antipsychotic, does not impair learning and memory in mouse passive avoidance

Schizophrenia research, 2001-04, Vol.49 (1), p.193-201

2001

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Potential role of muscarinic receptors in schizophrenia

Life sciences (1973), 1999, Vol.64 (6), p.527-534

1999

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Receptor reserve of phosphoinositide-coupled muscarinic receptors in mouse hippocampus in vivo

Brain research, 2001-10, Vol.916 (1), p.165-171

2001

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1-(1,2,5-Thiadiazol-4-yl)-4-azatricyclo[2.2.1.02,6]heptanes as New Potent Muscarinic M1 Agonists: Structure−Activity Relationship for 3-Aryl-2-propyn-1-yloxy and 3-Aryl-2-propyn-1-ylthio Derivatives

Journal of medicinal chemistry, 1999-06, Vol.42 (11), p.1999-2006

1999

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The antibody-capture [ 35S]GTPγS scintillation proximity assay: a powerful emerging technique for analysis of GPCR pharmacology

Trends in pharmacological sciences (Regular ed.), 2004-08, Vol.25 (8), p.400-401

DeLapp, Neil W.

2004

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Antagonism by olanzapine of dopamine D1, serotonin2, muscarinic, histamine H1 and α1-adrenergic receptors in vitro

Schizophrenia research, 1999-05, Vol.37 (1), p.107-122

1999

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The muscarinic M1 agonist xanomeline increases soluble amyloid precursor protein release from chinese hamster ovary-m1 cells

Life sciences (1973), 1995, Vol.57 (12), p.1183-1190

1995

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Butylthio[2.2.2] (NNC 11-1053/LY297802): an orally active muscarinic agonist analgesic

The Journal of pharmacology and experimental therapeutics, 1997-05, Vol.281 (2), p.876

1997

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Pharmacology of butylthio[2.2.2] (LY297802/NNC11-1053): a novel analgesic with mixed muscarinic receptor agonist and antagonist activity

The Journal of pharmacology and experimental therapeutics, 1997-05, Vol.281 (2), p.884

1997

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Effect of Basic Fibroblast Growth Factor (bFGF) and Insulin-Like Growth Factors Type I (IGF-I) and Type II (IGF-II) on Adult Human Keratinocyte Growth and Fibronectin Secretion

Journal of investigative dermatology, 1990-06, Vol.94 (6), p.777-780

1990

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Conformationally Constrained Analogues of the Muscarinic Agonist 3-(4-(Methylthio)-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine. Synthesis, Receptor Affinity, and Antinociceptive Activity

Journal of medicinal chemistry, 1998-01, Vol.41 (1), p.109-116

1998

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Potent antagonism of 5-HT3 and 5-HT6 receptors by olanzapine

European journal of pharmacology, 2001-11, Vol.430 (2-3), p.341-349

2001

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Muscarinic agonist inhibition of rat striatal adenylate cyclase is enhanced by dopamine stimulation

Life sciences (1973), 1996, Vol.59 (7), p.565-572

1996

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In vitro and in vivo biochemistry of olanzapine: a novel, atypical antipsychotic drug

Intrathecal pertussis toxin produces hyperalgesia and allodynia in mice

The minimum significant ratio: a statistical parameter to characterize the reproducibility of potency estimates from concentration-response assays and estimation by replicate-experiment studies

Muscarinic receptor agonists decrease cocaine self-administration rates in drug-naive mice

Unexpected antipsychotic-like activity with the muscarinic receptor ligand (5 R,6 R)6-(3-propylthio-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane

M1 muscarinic receptor signaling in mouse hippocampus and cortex

Muscarinic Agonists with Antipsychotic-like Activity: Structure−Activity Relationships of 1,2,5-Thiadiazole Analogues with Functional Dopamine Antagonist Activity

Determination of [35S]guanosine-5'-O-(3-thio)triphosphate binding mediated by cholinergic muscarinic receptors in membranes from Chinese hamster ovary cells and rat striatum using an anti-G protein scintillation proximity assay

Muscarinic agonists exhibit functional dopamine antagonism in unilaterally 6-OHDA lesioned rats

Forskolin Stimulation of Cyclic AMP Accumulation in Rat Brain Cortex Slices Is Markedly Enhanced by Endogenous Adenosine

Identification of side chains on 1,2,5-thiadiazole-azacycles optimal for muscarinic M1 receptor activation

Muscarinic receptor agonists, like dopamine receptor antagonist antipsychotics, inhibit conditioned avoidance response in rats

The muscarinic receptor agonist BuTAC, a novel potential antipsychotic, does not impair learning and memory in mouse passive avoidance

Potential role of muscarinic receptors in schizophrenia

Receptor reserve of phosphoinositide-coupled muscarinic receptors in mouse hippocampus in vivo

1-(1,2,5-Thiadiazol-4-yl)-4-azatricyclo[2.2.1.02,6]heptanes as New Potent Muscarinic M1 Agonists: Structure−Activity Relationship for 3-Aryl-2-propyn-1-yloxy and 3-Aryl-2-propyn-1-ylthio Derivatives

The antibody-capture [ 35S]GTPγS scintillation proximity assay: a powerful emerging technique for analysis of GPCR pharmacology

Antagonism by olanzapine of dopamine D1, serotonin2, muscarinic, histamine H1 and α1-adrenergic receptors in vitro

The muscarinic M1 agonist xanomeline increases soluble amyloid precursor protein release from chinese hamster ovary-m1 cells

Butylthio[2.2.2] (NNC 11-1053/LY297802): an orally active muscarinic agonist analgesic

Pharmacology of butylthio[2.2.2] (LY297802/NNC11-1053): a novel analgesic with mixed muscarinic receptor agonist and antagonist activity

Effect of Basic Fibroblast Growth Factor (bFGF) and Insulin-Like Growth Factors Type I (IGF-I) and Type II (IGF-II) on Adult Human Keratinocyte Growth and Fibronectin Secretion

Conformationally Constrained Analogues of the Muscarinic Agonist 3-(4-(Methylthio)-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine. Synthesis, Receptor Affinity, and Antinociceptive Activity

Potent antagonism of 5-HT3 and 5-HT6 receptors by olanzapine

Muscarinic agonist inhibition of rat striatal adenylate cyclase is enhanced by dopamine stimulation

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