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Update on melatonin receptors: IUPHAR Review 20

British journal of pharmacology, 2016-09, Vol.173 (18), p.2702-2725

2016

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International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, classification, and pharmacology of G protein-coupled melatonin receptors

Pharmacological reviews, 2010-09, Vol.62 (3), p.343

2010

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Mathematical modeling of the microtubule detyrosination/tyrosination cycle for cell-based drug screening design

PLoS computational biology, 2022-06, Vol.18 (6), p.e1010236-e1010236

2022

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Convergence of Melatonin and Serotonin (5-HT) Signaling at MT2/5-HT2C Receptor Heteromers

The Journal of biological chemistry, 2015-05, Vol.290 (18), p.11537-11546

2015

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GPR50-Ctail cleavage and nuclear translocation: a new signal transduction mode for G protein-coupled receptors

Cellular and molecular life sciences : CMLS, 2020-12, Vol.77 (24), p.5189-5205

2020

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Importance of the second extracellular loop for melatonin MT1 receptor function and absence of melatonin binding in GPR50

British journal of pharmacology, 2018-08, Vol.175 (16), p.3281-3297

2018

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The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization

The EMBO journal, 2006-07, Vol.25 (13), p.3012-3023

2006

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Molecular tools to study melatonin pathways and actions

Trends in pharmacological sciences (Regular ed.), 2005-08, Vol.26 (8), p.412-419

2005

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Daily variation in the electrophysiological activity of mouse medial habenula neurones

The Journal of physiology, 2014-02, Vol.592 (4), p.587-603

2014

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The orphan GPR50 receptor promotes constitutive TGFβ receptor signaling and protects against cancer development

Nature communications, 2018-03, Vol.9 (1), p.1216-15, Article 1216

2018

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Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons

Journal of pineal research, 2016-01, Vol.60 (1), p.95-108

2016

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Preferential Formation of MT1/MT2 Melatonin Receptor Heterodimers with Distinct Ligand Interaction Properties Compared with MT2 Homodimers

Molecular pharmacology, 2004-08, Vol.66 (2), p.312-321

2004

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X‐ray structural studies of quinone reductase 2 nanomolar range inhibitors

Protein science, 2011-07, Vol.20 (7), p.1182-1195

2011

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Hamster Melatonin Receptors: Cloning and Binding Characterization of MT1 and Attempt to Clone MT2

International journal of molecular sciences, 2018-07, Vol.19 (7), p.1957

2018

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Recombinant human melatonin receptor MT1 isolated in mixed detergents shows pharmacology similar to that in mammalian cell membranes

PloS one, 2014-06, Vol.9 (6), p.e100616-e100616

2014

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Expression of the orphan GPR50 protein in rodent and human dorsomedial hypothalamus, tanycytes and median eminence

Journal of pineal research, 2010-04, Vol.48 (3), p.263-269

2010

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Purification and Identification of G Protein-coupled Receptor Protein Complexes under Native Conditions

Molecular & cellular proteomics, 2007-05, Vol.6 (5), p.835-844

2007

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Functional Expression of MT2 (Mel1b) Melatonin Receptors in Human PAZ6 Adipocytes

Endocrinology (Philadelphia), 2001-10, Vol.142 (10), p.4264-4271

2001

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Novel conformationally constrained analogues of agomelatine as new melatoninergic ligands

Molecules (Basel, Switzerland), 2012-12, Vol.18 (1), p.154-166

2012

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New ligands at the melatonin binding site MT3

European journal of medicinal chemistry, 2006-03, Vol.41 (3), p.306-320

2006

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New radioligands for describing the molecular pharmacology of MT1 and MT2 melatonin receptors

International journal of molecular sciences, 2013-04, Vol.14 (5), p.8948-8962

2013

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Synthesis and Structure−Affinity−Activity Relationships of Novel Benzofuran Derivatives as MT2 Melatonin Receptor Selective Ligands

Journal of medicinal chemistry, 2002-06, Vol.45 (13), p.2788-2800

2002

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A Generic Approach for the Purification of Signaling Complexes That Specifically Interact with the Carboxyl-terminal Domain of G Protein-coupled Receptors

Molecular & cellular proteomics, 2008-08, Vol.7 (8), p.1556-1569

2008

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Mathematical modeling of the microtubule detyrosination/tyrosination cycle for cell-based drug screening design

PLoS computational biology, 2022-06, Vol.18 (6)

2022

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Negative regulation of melatonin secretion by melatonin receptors in ovine pinealocytes

PloS one, 2021-07, Vol.16 (7), p.1-20

2021

Volltextzugriff (PDF)

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Update on melatonin receptors: IUPHAR Review 20

International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, classification, and pharmacology of G protein-coupled melatonin receptors

Mathematical modeling of the microtubule detyrosination/tyrosination cycle for cell-based drug screening design

Convergence of Melatonin and Serotonin (5-HT) Signaling at MT2/5-HT2C Receptor Heteromers

GPR50-Ctail cleavage and nuclear translocation: a new signal transduction mode for G protein-coupled receptors

Importance of the second extracellular loop for melatonin MT1 receptor function and absence of melatonin binding in GPR50

The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization

Molecular tools to study melatonin pathways and actions

Daily variation in the electrophysiological activity of mouse medial habenula neurones

The orphan GPR50 receptor promotes constitutive TGFβ receptor signaling and protects against cancer development

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons

Preferential Formation of MT1/MT2 Melatonin Receptor Heterodimers with Distinct Ligand Interaction Properties Compared with MT2 Homodimers

X‐ray structural studies of quinone reductase 2 nanomolar range inhibitors

Hamster Melatonin Receptors: Cloning and Binding Characterization of MT1 and Attempt to Clone MT2

Recombinant human melatonin receptor MT1 isolated in mixed detergents shows pharmacology similar to that in mammalian cell membranes

Expression of the orphan GPR50 protein in rodent and human dorsomedial hypothalamus, tanycytes and median eminence

Purification and Identification of G Protein-coupled Receptor Protein Complexes under Native Conditions

Functional Expression of MT2 (Mel1b) Melatonin Receptors in Human PAZ6 Adipocytes

Novel conformationally constrained analogues of agomelatine as new melatoninergic ligands

New ligands at the melatonin binding site MT3

New radioligands for describing the molecular pharmacology of MT1 and MT2 melatonin receptors

Synthesis and Structure−Affinity−Activity Relationships of Novel Benzofuran Derivatives as MT2 Melatonin Receptor Selective Ligands

A Generic Approach for the Purification of Signaling Complexes That Specifically Interact with the Carboxyl-terminal Domain of G Protein-coupled Receptors

Mathematical modeling of the microtubule detyrosination/tyrosination cycle for cell-based drug screening design

Negative regulation of melatonin secretion by melatonin receptors in ovine pinealocytes

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