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Motor and non-motor circuit disturbances in early Parkinson disease: which happens first?

Nature reviews. Neuroscience, 2022-02, Vol.23 (2), p.115

2022

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Protein aggregation and neurodegeneration in prototypical neurodegenerative diseases: Examples of amyloidopathies, tauopathies and synucleinopathies

Progress in neurobiology, 2017-08, Vol.155, p.171-193

2017

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Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling

Nature communications, 2020-07, Vol.11 (1), p.3440-3440, Article 3440

2020

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PLGA-Based Nanoparticles for Neuroprotective Drug Delivery in Neurodegenerative Diseases

Pharmaceutics, 2021-07, Vol.13 (7), p.1042

2021

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Pathogenic lysosomal depletion in Parkinson's disease

The Journal of neuroscience, 2010-09, Vol.30 (37), p.12535-12544

2010

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Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations

Lancet neurology, 2015-08, Vol.14 (8), p.855-866

2015

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Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration

Proceedings of the National Academy of Sciences - PNAS, 2012-06, Vol.109 (24), p.9611-9616

2012

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Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates

Brain (London, England : 1878), 2020-05, Vol.143 (5), p.1462-1475

2020

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Alpha-synuclein propagation: New insights from animal models

Movement disorders, 2016-02, Vol.31 (2), p.161-168

2016

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What lysosomes actually tell us about Parkinson’s disease?

Ageing research reviews, 2016-12, Vol.32, p.140-149

2016

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Lysosomal impairment in Parkinson's disease

Movement disorders, 2013-06, Vol.28 (6), p.725-732

2013

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Pathogenic Aspects and Therapeutic Avenues of Autophagy in Parkinson's Disease

Cells (Basel, Switzerland), 2023-02, Vol.12 (4), p.621

2023

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Autophagy in Synucleinopathy: The Overwhelmed and Defective Machinery

Cells (Basel, Switzerland), 2019-06, Vol.8 (6), p.565

2019

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In vitro α-synuclein neurotoxicity and spreading among neurons and astrocytes using Lewy body extracts from Parkinson disease brains

Neurobiology of disease, 2017-07, Vol.103, p.101-112

2017

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Critical Role of the Proline-rich Region in Huntingtin for Aggregation and Cytotoxicity in Yeast

The Journal of biological chemistry, 2006-11, Vol.281 (47), p.35608-35615

2006

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Multiple System Atrophy: Recent Developments and Future Perspectives

Movement disorders, 2019-11, Vol.34 (11), p.1629-1642

2019

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CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease

Nature communications, 2020-09, Vol.11 (1), p.4885-4885, Article 4885

2020

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Functional and neuropathological changes induced by injection of distinct alpha-synuclein strains: A pilot study in non-human primates

Neurobiology of disease, 2023-05, Vol.180, p.106086-106086, Article 106086

2023

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PSD-95 expression controls L-DOPA dyskinesia through dopamine D1 receptor trafficking

The Journal of clinical investigation, 2012-11, Vol.122 (11), p.3977-3989

2012

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Targeting α-synuclein for PD Therapeutics: A Pursuit on All Fronts

Biomolecules (Basel, Switzerland), 2020-03, Vol.10 (3), p.391

2020

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Use of adeno-associated virus-mediated delivery of mutant huntingtin to study the spreading capacity of the protein in mice and non-human primates

Neurobiology of disease, 2020-07, Vol.141, p.104951-104951, Article 104951

2020

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Evaluation of blood flow as a route for propagation in experimental synucleinopathy

Neurobiology of disease, 2021-03, Vol.150, p.105255-105255, Article 105255

2021

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RGS9‐2 rescues dopamine D2 receptor levels and signaling in DYT1 dystonia mouse models

EMBO molecular medicine, 2019-01, Vol.11 (1), p.n/a

2019

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Evidence for the spread of human-derived mutant huntingtin protein in mice and non-human primates

Neurobiology of disease, 2020-07, Vol.141, p.104941-104941, Article 104941

2020

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Lysosomal dysfunction in Parkinson disease: ATP13A2 gets into the groove

Autophagy, 2012-09, Vol.8 (9), p.1389-1391

2012

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Motor and non-motor circuit disturbances in early Parkinson disease: which happens first?

Protein aggregation and neurodegeneration in prototypical neurodegenerative diseases: Examples of amyloidopathies, tauopathies and synucleinopathies

Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling

PLGA-Based Nanoparticles for Neuroprotective Drug Delivery in Neurodegenerative Diseases

Pathogenic lysosomal depletion in Parkinson's disease

Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations

Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration

Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates

Alpha-synuclein propagation: New insights from animal models

What lysosomes actually tell us about Parkinson’s disease?

Lysosomal impairment in Parkinson's disease

Pathogenic Aspects and Therapeutic Avenues of Autophagy in Parkinson's Disease

Autophagy in Synucleinopathy: The Overwhelmed and Defective Machinery

In vitro α-synuclein neurotoxicity and spreading among neurons and astrocytes using Lewy body extracts from Parkinson disease brains

Critical Role of the Proline-rich Region in Huntingtin for Aggregation and Cytotoxicity in Yeast

Multiple System Atrophy: Recent Developments and Future Perspectives

CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease

Functional and neuropathological changes induced by injection of distinct alpha-synuclein strains: A pilot study in non-human primates

PSD-95 expression controls L-DOPA dyskinesia through dopamine D1 receptor trafficking

Targeting α-synuclein for PD Therapeutics: A Pursuit on All Fronts

Use of adeno-associated virus-mediated delivery of mutant huntingtin to study the spreading capacity of the protein in mice and non-human primates

Evaluation of blood flow as a route for propagation in experimental synucleinopathy

RGS9‐2 rescues dopamine D2 receptor levels and signaling in DYT1 dystonia mouse models

Evidence for the spread of human-derived mutant huntingtin protein in mice and non-human primates

Lysosomal dysfunction in Parkinson disease: ATP13A2 gets into the groove

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