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Staying true to yourself: mechanisms of DNA methylation maintenance in mammals

Nucleic acids research, 2021-04, Vol.49 (6), p.3020-3032

2021

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Lysine Methylation Regulators Moonlighting outside the Epigenome

Molecular cell, 2019-09, Vol.75 (6), p.1092-1101

2019

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The nuclear receptor RXRA controls cellular senescence by regulating calcium signaling

Aging cell, 2018-12, Vol.17 (6), p.e12831-n/a

2018

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Methylation of DNA Ligase 1 by G9a/GLP Recruits UHRF1 to Replicating DNA and Regulates DNA Methylation

Molecular cell, 2017-08, Vol.67 (4), p.550-565.e5

2017

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Context-dependent CpG methylation directs cell-specific binding of transcription factor ZBTB38

Epigenetics, 2022-12, Vol.17 (13), p.2122-2143

2022

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Born to bind: the BTB protein-protein interaction domain

BioEssays, 2006-12, Vol.28 (12), p.1194-1202

2006

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Loss of the Methyl-CpG-Binding Protein ZBTB4 Alters Mitotic Checkpoint, Increases Aneuploidy, and Promotes Tumorigenesis

Cancer research (Chicago, Ill.), 2017-01, Vol.77 (1), p.62-73

2017

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Structural basis for activation of DNMT1

Nature communications, 2022-11, Vol.13 (1), p.7130-7130, Article 7130

2022

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Unchanged PCNA and DNMT1 dynamics during replication in DNA ligase I-deficient cells but abnormal chromatin levels of non-replicative histone H1

Scientific reports, 2023-03, Vol.13 (1), p.4363-4363, Article 4363

2023

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Structure of the UHRF1 Tandem Tudor Domain Bound to a Methylated Non-histone Protein, LIG1, Reveals Rules for Binding and Regulation

Structure (London), 2019-03, Vol.27 (3), p.485-496.e7

2019

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MBD5 and MBD6 interact with the human PR-DUB complex through their methyl-CpG-binding domain

Proteomics (Weinheim), 2014-10, Vol.14 (19), p.2179-2189

2014

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The cell biology of DNA methylation in mammals

Biochimica et biophysica acta, 2008-11, Vol.1783 (11), p.2167-2173

2008

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On how mammalian transcription factors recognize methylated DNA

Epigenetics, 2013-02, Vol.8 (2), p.131-137

2013

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Mechanisms of DNA Methyltransferase Recruitment in Mammals

Genes, 2018-12, Vol.9 (12), p.617

2018

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Stabilization of the methyl-CpG binding protein ZBTB38 by the deubiquitinase USP9X limits the occurrence and toxicity of oxidative stress in human cells

Nucleic acids research, 2018-05, Vol.46 (9), p.4392-4404

2018

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Large-Scale Chromatin Rearrangements in Cancer

Cancers, 2022-05, Vol.14 (10), p.2384

2022

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Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells

Nature communications, 2024-04, Vol.15 (1), p.2960-2960, Article 2960

2024

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Ceci n'est pas une DNMT: Recently discovered functions of DNMT2 and their relation to methyltransferase activity (Comment on DOI 10.1002/bies.201300088)

BioEssays, 2013-12, Vol.35 (12), p.1024-1024

Defossez, Pierre-Antoine

2013

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A Family of Human Zinc Finger Proteins That Bind Methylated DNA and Repress Transcription

Molecular and Cellular Biology, 2006-01, Vol.26 (1), p.169-181

2006

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RSK3 switches cell fate: from stress-induced senescence to malignant progression

Journal of experimental & clinical cancer research, 2023-11, Vol.42 (1), p.1-318, Article 318

2023

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Genetic screens reveal mechanisms for the transcriptional regulation of tissue-specific genes in normal cells and tumors

Nucleic acids research, 2019-04, Vol.47 (7), p.3407-3421

2019

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Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration

Nature (London), 2002-07, Vol.418 (6895), p.344-348

2002

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Zbtb4 represses transcription of P21CIP1 and controls the cellular response to p53 activation

The EMBO journal, 2008-06, Vol.27 (11), p.1563-1574

2008

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The human proteins MBD5 and MBD6 associate with heterochromatin but they do not bind methylated DNA

PloS one, 2010-08, Vol.5 (8), p.e11982-e11982

2010

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Locus-level L1 DNA methylation profiling reveals the epigenetic and transcriptional interplay between L1s and their integration sites

Cell genomics, 2024-02, Vol.4 (2), p.100498-100498, Article 100498

2024

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Staying true to yourself: mechanisms of DNA methylation maintenance in mammals

Lysine Methylation Regulators Moonlighting outside the Epigenome

The nuclear receptor RXRA controls cellular senescence by regulating calcium signaling

Methylation of DNA Ligase 1 by G9a/GLP Recruits UHRF1 to Replicating DNA and Regulates DNA Methylation

Context-dependent CpG methylation directs cell-specific binding of transcription factor ZBTB38

Born to bind: the BTB protein-protein interaction domain

Loss of the Methyl-CpG-Binding Protein ZBTB4 Alters Mitotic Checkpoint, Increases Aneuploidy, and Promotes Tumorigenesis

Structural basis for activation of DNMT1

Unchanged PCNA and DNMT1 dynamics during replication in DNA ligase I-deficient cells but abnormal chromatin levels of non-replicative histone H1

Structure of the UHRF1 Tandem Tudor Domain Bound to a Methylated Non-histone Protein, LIG1, Reveals Rules for Binding and Regulation

MBD5 and MBD6 interact with the human PR-DUB complex through their methyl-CpG-binding domain

The cell biology of DNA methylation in mammals

On how mammalian transcription factors recognize methylated DNA

Mechanisms of DNA Methyltransferase Recruitment in Mammals

Stabilization of the methyl-CpG binding protein ZBTB38 by the deubiquitinase USP9X limits the occurrence and toxicity of oxidative stress in human cells

Large-Scale Chromatin Rearrangements in Cancer

Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells

Ceci n'est pas une DNMT: Recently discovered functions of DNMT2 and their relation to methyltransferase activity (Comment on DOI 10.1002/bies.201300088)

A Family of Human Zinc Finger Proteins That Bind Methylated DNA and Repress Transcription

RSK3 switches cell fate: from stress-induced senescence to malignant progression

Genetic screens reveal mechanisms for the transcriptional regulation of tissue-specific genes in normal cells and tumors

Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration

Zbtb4 represses transcription of P21CIP1 and controls the cellular response to p53 activation

The human proteins MBD5 and MBD6 associate with heterochromatin but they do not bind methylated DNA

Locus-level L1 DNA methylation profiling reveals the epigenetic and transcriptional interplay between L1s and their integration sites

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