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Cofilin under control of β-arrestin-2 in NMDA-dependent dendritic spine plasticity, long-term depression (LTD), and learning

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (7), p.2208-2208

2012

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Beta-arrestins as regulators of signal termination and transduction: How do they determine what to scaffold?

Cellular signalling, 2011-04, Vol.23 (4), p.621-629

DeFea, Kathryn A.

2011

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β-Arrestin-2 mediates the proinflammatory effects of proteinase-activated receptor-2 in the airway

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (41), p.16660-16665

2012

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Differential regulation of class IA phosphoinositide 3-kinase catalytic subunits p110 alpha and beta by protease-activated receptor 2 and beta-arrestins

Biochemical journal, 2007-12, Vol.408 (2), p.221-230

2007

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A Transmembrane Form of the Prion Protein in Neurodegenerative Disease

Science (American Association for the Advancement of Science), 1998-02, Vol.279 (5352), p.827-834

1998

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Protease-Activated Receptor 2 (PAR2) Expressed in Sensory Neurons Contributes to Signs of Pain and Neuropathy in Paclitaxel Treated Mice

The journal of pain, 2023-11, Vol.24 (11), p.1980-1993

2023

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Stop that cell! Beta-arrestin-dependent chemotaxis: a tale of localized actin assembly and receptor desensitization

Annual review of physiology, 2007-01, Vol.69 (1), p.535-560

DeFea, Kathryn A

2007

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Neutrophil Elastase Acts as a Biased Agonist for Proteinase-activated Receptor-2 (PAR2)

The Journal of biological chemistry, 2011-07, Vol.286 (28), p.24638-24648

2011

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Alternaria alternata-induced airway epithelial signaling and inflammatory responses via protease-activated receptor-2 expression

Biochemical and biophysical research communications, 2022-02, Vol.591, p.13-19

2022

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C781, a β-Arrestin Biased Antagonist at Protease-Activated Receptor-2 (PAR2), Displays in vivo Efficacy Against Protease-Induced Pain in Mice

The journal of pain, 2023-04, Vol.24 (4), p.605-616

2023

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β‐Arrestin‐biased proteinase‐activated receptor‐2 antagonist C781 limits allergen‐induced airway hyperresponsiveness and inflammation

British journal of pharmacology, 2023-03, Vol.180 (5), p.667-680

2023

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Proteinase‐activated receptor‐2 antagonist C391 inhibits Alternaria‐induced airway epithelial signalling and asthma indicators in acute exposure mouse models

British journal of pharmacology, 2022-05, Vol.179 (10), p.2208-2222

2022

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β-Arrestin-dependent Regulation of the Cofilin Pathway Downstream of Protease-activated Receptor-2

The Journal of biological chemistry, 2007-07, Vol.282 (28), p.20634-20646

2007

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Focal Adhesion Kinase Acts Downstream of EphB Receptors to Maintain Mature Dendritic Spines by Regulating Cofilin Activity

The Journal of neuroscience, 2009-06, Vol.29 (25), p.8129-8142

2009

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Protease-activated receptor-2 signaling through β-arrestin-2 mediates Alternaria alkaline serine protease-induced airway inflammation

American journal of physiology. Lung cellular and molecular physiology, 2018-12, Vol.315 (6), p.L1042-L1057

2018

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β-Arrestins Scaffold Cofilin with Chronophin to Direct Localized Actin Filament Severing and Membrane Protrusions Downstream of Protease-activated Receptor-2

The Journal of biological chemistry, 2010-05, Vol.285 (19), p.14318-14329

2010

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Apical and basolateral pools of proteinase-activated receptor-2 direct distinct signaling events in the intestinal epithelium

American Journal of Physiology: Cell Physiology, 2011-01, Vol.300 (1), p.C113-C123

2011

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The novel PAR2 ligand C391 blocks multiple PAR2 signalling pathways in vitro and in vivo

British journal of pharmacology, 2015-09, Vol.172 (18), p.4535-4545

2015

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Protease-Activated Receptor-2 Simultaneously Directs β-Arrestin-1-Dependent Inhibition and Gαq-Dependent Activation of Phosphatidylinositol 3-Kinase

Biochemistry (Easton), 2006-08, Vol.45 (31), p.9374-9385

2006

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Molecular mechanisms underlying beta-arrestin-dependent chemotaxis and actin-cytoskeletal reorganization

Handbook of experimental pharmacology, 2014, Vol.219, p.341

2014

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β-Arrestin-kinase scaffolds: turn them on or turn them off?

Wiley interdisciplinary reviews. Systems biology and medicine, 2013-03, Vol.5 (2), p.231-241

2013

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Beta-arrestin inhibits CAMKKbeta-dependent AMPK activation downstream of protease-activated-receptor-2

BMC biochemistry, 2010-09, Vol.11 (1), p.36-36, Article 36

2010

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Arrestins in Actin Reorganization and Cell Migration

Progress in Molecular Biology and Translational Science, 2013, Vol.118, p.205-222

DeFea, Kathryn A.

2013

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Effect of PAR-2 Deficiency in Mice on KC Expression after Intratracheal LPS Administration

Journal of Signal Transduction, 2011-01, Vol.2011 (2011), p.118-123

2011

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Protein kinase C-mediated desensitization of the neurokinin 1 receptor

American Journal of Physiology: Cell Physiology, 2001-05, Vol.280 (5), p.C1097-C1106

2001

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Cofilin under control of β-arrestin-2 in NMDA-dependent dendritic spine plasticity, long-term depression (LTD), and learning

Beta-arrestins as regulators of signal termination and transduction: How do they determine what to scaffold?

β-Arrestin-2 mediates the proinflammatory effects of proteinase-activated receptor-2 in the airway

Differential regulation of class IA phosphoinositide 3-kinase catalytic subunits p110 alpha and beta by protease-activated receptor 2 and beta-arrestins

A Transmembrane Form of the Prion Protein in Neurodegenerative Disease

Protease-Activated Receptor 2 (PAR2) Expressed in Sensory Neurons Contributes to Signs of Pain and Neuropathy in Paclitaxel Treated Mice

Stop that cell! Beta-arrestin-dependent chemotaxis: a tale of localized actin assembly and receptor desensitization

Neutrophil Elastase Acts as a Biased Agonist for Proteinase-activated Receptor-2 (PAR2)

Alternaria alternata-induced airway epithelial signaling and inflammatory responses via protease-activated receptor-2 expression

C781, a β-Arrestin Biased Antagonist at Protease-Activated Receptor-2 (PAR2), Displays in vivo Efficacy Against Protease-Induced Pain in Mice

β‐Arrestin‐biased proteinase‐activated receptor‐2 antagonist C781 limits allergen‐induced airway hyperresponsiveness and inflammation

Proteinase‐activated receptor‐2 antagonist C391 inhibits Alternaria‐induced airway epithelial signalling and asthma indicators in acute exposure mouse models

β-Arrestin-dependent Regulation of the Cofilin Pathway Downstream of Protease-activated Receptor-2

Focal Adhesion Kinase Acts Downstream of EphB Receptors to Maintain Mature Dendritic Spines by Regulating Cofilin Activity

Protease-activated receptor-2 signaling through β-arrestin-2 mediates Alternaria alkaline serine protease-induced airway inflammation

β-Arrestins Scaffold Cofilin with Chronophin to Direct Localized Actin Filament Severing and Membrane Protrusions Downstream of Protease-activated Receptor-2

Apical and basolateral pools of proteinase-activated receptor-2 direct distinct signaling events in the intestinal epithelium

The novel PAR2 ligand C391 blocks multiple PAR2 signalling pathways in vitro and in vivo

Protease-Activated Receptor-2 Simultaneously Directs β-Arrestin-1-Dependent Inhibition and Gαq-Dependent Activation of Phosphatidylinositol 3-Kinase

Molecular mechanisms underlying beta-arrestin-dependent chemotaxis and actin-cytoskeletal reorganization

β-Arrestin-kinase scaffolds: turn them on or turn them off?

Beta-arrestin inhibits CAMKKbeta-dependent AMPK activation downstream of protease-activated-receptor-2

Arrestins in Actin Reorganization and Cell Migration

Effect of PAR-2 Deficiency in Mice on KC Expression after Intratracheal LPS Administration

Protein kinase C-mediated desensitization of the neurokinin 1 receptor

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