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Fundamental trade-offs between information flow in single cells and cellular populations

Proceedings of the National Academy of Sciences - PNAS, 2017-05, Vol.114 (22), p.5755-5760

2017

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Crosstalk and the evolution of specificity in two-component signaling

Proceedings of the National Academy of Sciences - PNAS, 2014-04, Vol.111 (15), p.5550-5555

2014

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Novel metrics reveal new structure and unappreciated heterogeneity in Caenorhabditis elegans development

PLoS computational biology, 2023-12, Vol.19 (12), p.e1011733

2023

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Machines vs. ensembles: effective MAPK signaling through heterogeneous sets of protein complexes

PLoS computational biology, 2013-10, Vol.9 (10), p.e1003278-e1003278

2013

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Sizing up allometric scaling theory

PLoS computational biology, 2008-09, Vol.4 (9), p.e1000171-e1000171

2008

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Crosstalk and Competition in Signaling Networks

Biophysical journal, 2012-12, Vol.103 (11), p.2389-2398

2012

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Crosstalk and ultrasensitivity in protein degradation pathways

PLoS computational biology, 2020-12, Vol.16 (12), p.e1008492-e1008492

2020

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Crosstalk and the evolvability of intracellular communication

Nature communications, 2017-07, Vol.8 (1), p.16009-16009, Article 16009

2017

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Combinatorial complexity and compositional drift in protein interaction networks

PloS one, 2012-03, Vol.7 (3), p.e32032-e32032

2012

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Machine learning classification can reduce false positives in structure-based virtual screening

Proceedings of the National Academy of Sciences - PNAS, 2020-08, Vol.117 (31), p.18477-18488

2020

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Phosphatase Specificity and Pathway Insulation in Signaling Networks

Biophysical journal, 2015-02, Vol.108 (4), p.986-996

2015

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Optimizing ring assembly reveals the strength of weak interactions

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (7), p.2348-2353

2012

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Mathematical Model for Length Control by the Timing of Substrate Switching in the Type III Secretion System

PLoS computational biology, 2016-04, Vol.12 (4), p.e1004851-e1004851

2016

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Curvature in metabolic scaling

Nature (London), 2010-04, Vol.464 (7289), p.753-756

2010

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Robust protein-protein interactions in crowded cellular environments

Proceedings of the National Academy of Sciences - PNAS, 2007-09, Vol.104 (38), p.14952-14957

2007

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Understanding the separation of timescales in bacterial proteasome core particle assembly

Biophysical journal, 2022-10, Vol.121 (20), p.3975-3986

2022

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A Simple Physical Model for Scaling in Protein-Protein Interaction Networks

Proceedings of the National Academy of Sciences - PNAS, 2006-01, Vol.103 (2), p.311-316

2006

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Modeling reveals the strength of weak interactions in stacked-ring assembly

Biophysical journal, 2024-07, Vol.123 (13), p.1763-1780

2024

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Binomial models uncover biological variation during feature selection of droplet-based single-cell RNA sequencing

PLoS computational biology, 2024-09, Vol.20 (9), p.e1012386

2024

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Understanding Ensemble Protein Folding at Atomic Detail

Proceedings of the National Academy of Sciences - PNAS, 2006-11, Vol.103 (47), p.17747-17752

2006

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Docking-based long timescale simulation of cell-size protein systems at atomic resolution

Proceedings of the National Academy of Sciences - PNAS, 2022-10, Vol.119 (41), p.e2210249119-8

2022

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Computational approaches to macromolecular interactions in the cell

Current opinion in structural biology, 2019-04, Vol.55, p.59-65

2019

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Robustness and the evolution of length control strategies in the T3SS and flagellar hook

Biophysical journal, 2021-09, Vol.120 (17), p.3820-3830

2021

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Cooperativity in Proteasome Core Particle Maturation

iScience, 2020-05, Vol.23 (5), p.101090-101090, Article 101090

2020

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Structural Properties of Non-Traditional Drug Targets Present New Challenges for Virtual Screening

Journal of chemical information and modeling, 2013-08, Vol.53 (8), p.2073-2081

2013

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Fundamental trade-offs between information flow in single cells and cellular populations

Crosstalk and the evolution of specificity in two-component signaling

Novel metrics reveal new structure and unappreciated heterogeneity in Caenorhabditis elegans development

Machines vs. ensembles: effective MAPK signaling through heterogeneous sets of protein complexes

Sizing up allometric scaling theory

Crosstalk and Competition in Signaling Networks

Crosstalk and ultrasensitivity in protein degradation pathways

Crosstalk and the evolvability of intracellular communication

Combinatorial complexity and compositional drift in protein interaction networks

Machine learning classification can reduce false positives in structure-based virtual screening

Phosphatase Specificity and Pathway Insulation in Signaling Networks

Optimizing ring assembly reveals the strength of weak interactions

Mathematical Model for Length Control by the Timing of Substrate Switching in the Type III Secretion System

Curvature in metabolic scaling

Robust protein-protein interactions in crowded cellular environments

Understanding the separation of timescales in bacterial proteasome core particle assembly

A Simple Physical Model for Scaling in Protein-Protein Interaction Networks

Modeling reveals the strength of weak interactions in stacked-ring assembly

Binomial models uncover biological variation during feature selection of droplet-based single-cell RNA sequencing

Understanding Ensemble Protein Folding at Atomic Detail

Docking-based long timescale simulation of cell-size protein systems at atomic resolution

Computational approaches to macromolecular interactions in the cell

Robustness and the evolution of length control strategies in the T3SS and flagellar hook

Cooperativity in Proteasome Core Particle Maturation

Structural Properties of Non-Traditional Drug Targets Present New Challenges for Virtual Screening

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