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TBC3711, an ETA receptor antagonist, reduces neonatal hypoxia-induced pulmonary hypertension in piglets

Pediatric research, 2001-09, Vol.50 (3), p.374-383

2001

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Discovery, Modeling, and Human Pharmacokinetics of N-(2-Acetyl-4,6-dimethylphenyl)-3-(3,4-dimethylisoxazol-5-ylsulfamoyl)thiophene-2-carboxamide (TBC3711), a Second Generation, ETA Selective, and Orally Bioavailable Endothelin Antagonist

Journal of medicinal chemistry, 2004-04, Vol.47 (8), p.1969-1986

2004

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Potent in vivo suppression of inflammation by selectively targeting the high affinity conformation of integrin α4β1

Biochemical and biophysical research communications, 2010-10, Vol.400 (4), p.619-624

2010

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Acyl Substitution at the Ortho Position of Anilides Enhances Oral Bioavailability of Thiophene Sulfonamides: TBC3214, an ETA Selective Endothelin Antagonist

Journal of medicinal chemistry, 2001-04, Vol.44 (8), p.1211-1216

2001

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Discovery, Modeling, and Human Pharmacokinetics of N -(2-Acetyl-4,6-dimethylphenyl)-3-(3,4-dimethylisoxazol-5-ylsulfamoyl)thiophene-2-carboxamide (TBC3711), a Second Generation, ET A Selective, and Orally Bioavailable Endothelin Antagonist

Journal of medicinal chemistry, 2004-04, Vol.47 (8), p.1969-1986

2004

Volltextzugriff (PDF)

Discovery, modeling, and human pharmacokinetics of N-(2-acetyl-4,6-dimethylphenyl)-3-(3,4-dimethylisoxazol-5-ylsulfamoyl)-thiophene -2-carboxamide (TBC3711), a second generation, ETA selective, and orally bioavailable endothelin antagonists

Journal of medicinal chemistry, 2004, Vol.47 (8), p.1969-1986

2004

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Endothelin antagonists: substituted mesitylcarboxamides with high potency and selectivity for ET(A) receptors

Journal of medicinal chemistry, 1999-11, Vol.42 (22), p.4485-4499

1999

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Endothelin Antagonists: Substituted Mesitylcarboxamides with High Potency and Selectivity for ETA Receptors

Journal of medicinal chemistry, 1999-11, Vol.42 (22), p.4485-4499

1999

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Acyl Substitution at the Ortho Position of Anilides Enhances Oral Bioavailability of Thiophene Sulfonamides: TBC3214, an ET A Selective Endothelin Antagonist

Journal of medicinal chemistry, 2001-04, Vol.44 (8), p.1211-1216

2001

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Nonmuscle Myosin IIA Copurifies with Chloride Channel-Enriched Membranes from Epithelia

Biochemical and biophysical research communications, 1997-02, Vol.231 (2), p.369-372

1997

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Immunolocalization of chloride-transporting membrane vesicles in tracheal epithelial cells

American Journal of Physiology: Cell Physiology, 1992, Vol.32 (4), p.C888-C895

1992

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Comparison of the gramicidin a potassium/sodium permeability and single channel conductance ratio

Biochimica et biophysica acta. Biomembranes, 1983-04, Vol.730 (1), p.178-180

1983

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HYDROGEN ION CONDUCTANCE THROUGH THE GRAMICIDIN CHANNEL: THE ROLE OF AQUEOUS DIFFUSION (DIFFUSION LIMITATION, ELECTROSTATIC POTENTIAL)

DECKER, E RADFORD

1986

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Nonpeptide endothelin antagonists in clinical development

Drugs of today (Barcelona, Spain : 1998), 2001-07, Vol.37 (7), p.441-453

2001

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TBC3711, an ETA receptor antagonist, reduces neonatal hypoxia-induced pulmonary hypertension in piglets

Discovery, Modeling, and Human Pharmacokinetics of N-(2-Acetyl-4,6-dimethylphenyl)-3-(3,4-dimethylisoxazol-5-ylsulfamoyl)thiophene-2-carboxamide (TBC3711), a Second Generation, ETA Selective, and Orally Bioavailable Endothelin Antagonist

Potent in vivo suppression of inflammation by selectively targeting the high affinity conformation of integrin α4β1

Acyl Substitution at the Ortho Position of Anilides Enhances Oral Bioavailability of Thiophene Sulfonamides: TBC3214, an ETA Selective Endothelin Antagonist

Discovery, Modeling, and Human Pharmacokinetics of N -(2-Acetyl-4,6-dimethylphenyl)-3-(3,4-dimethylisoxazol-5-ylsulfamoyl)thiophene-2-carboxamide (TBC3711), a Second Generation, ET A Selective, and Orally Bioavailable Endothelin Antagonist

Discovery, modeling, and human pharmacokinetics of N-(2-acetyl-4,6-dimethylphenyl)-3-(3,4-dimethylisoxazol-5-ylsulfamoyl)-thiophene -2-carboxamide (TBC3711), a second generation, ETA selective, and orally bioavailable endothelin antagonists

Endothelin antagonists: substituted mesitylcarboxamides with high potency and selectivity for ET(A) receptors

Endothelin Antagonists: Substituted Mesitylcarboxamides with High Potency and Selectivity for ETA Receptors

Acyl Substitution at the Ortho Position of Anilides Enhances Oral Bioavailability of Thiophene Sulfonamides: TBC3214, an ET A Selective Endothelin Antagonist

Nonmuscle Myosin IIA Copurifies with Chloride Channel-Enriched Membranes from Epithelia

Immunolocalization of chloride-transporting membrane vesicles in tracheal epithelial cells

Comparison of the gramicidin a potassium/sodium permeability and single channel conductance ratio

HYDROGEN ION CONDUCTANCE THROUGH THE GRAMICIDIN CHANNEL: THE ROLE OF AQUEOUS DIFFUSION (DIFFUSION LIMITATION, ELECTROSTATIC POTENTIAL)

Nonpeptide endothelin antagonists in clinical development

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