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Breast cancer genomics and immuno-oncological markers to guide immune therapies

Seminars in cancer biology, 2018-10, Vol.52 (Pt 2), p.178-188

2018

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Intra-tumoral production of IL18, but not IL12, by TCR-engineered T cells is non-toxic and counteracts immune evasion of solid tumors

Oncoimmunology, 2018-01, Vol.7 (1), p.e1378842

2018

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B-cell clusters at the invasive margin associate with longer survival in early-stage oral-tongue cancer patients

Oncoimmunology, 2021-01, Vol.10 (1), p.1882743-1882743

2021

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Case Report: Adequate T and B Cell Responses in a SARS-CoV-2 Infected Patient After Immune Checkpoint Inhibition

Frontiers in immunology, 2021-02, Vol.12, p.627186

2021

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Two novel IL-1 family members, IL-1 delta and IL-1 epsilon, function as an antagonist and agonist of NF-kappa B activation through the orphan IL-1 receptor-related protein 2

The Journal of immunology (1950), 2001-08, Vol.167 (3), p.1440-1446

2001

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GMP protocol to gene-engineer and process human T-cells revisited: medium critically determines yield, function and differentiation state of CD8+ T-cells

Cytotherapy (Oxford, England), 2014-04, Vol.16 (4), p.S16-S16

2014

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A critical role for interleukin 18 in primary and memory effector responses to Listeria monocytogenes that extends beyond its effects on Interferon gamma production

The Journal of experimental medicine, 2001-08, Vol.194 (3), p.343-354

2001

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Redirecting human CD4 T lymphocytes to the MHC class I-restricted melanoma antigen MAGE-A1 by TCR αβ gene transfer requires CD8α

Gene therapy, 2005-01, Vol.12 (2), p.140-146

2005

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Cytokine Networking in Lungs of Immunocompetent Mice in Response to Inhaled Aspergillus fumigatus

Infection and Immunity, 2001-03, Vol.69 (3), p.1554-1560

2001

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999P NPC patients with post-RT EBV clearance show a higher frequency of peripheral CD8 T-cells expressing chemo-attractant receptors at baseline and during radiation therapy

Annals of oncology, 2021-09, Vol.32, p.S848-S849

2021

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OS10.5.A PERIVASCULAR CONTAINED T CELLS IN IDH-MUTANT ASTROCYTOMA CO-LOCALIZE WITH GEMISTOCYTIC TUMOR CELLS OF AN ASTROCYTE-STATE AND MACROPHAGES WITH AN IMMUNE-STIMULATORY PHENOTYPE

Neuro-oncology (Charlottesville, Va.), 2023-09, Vol.25 (Supplement_2), p.ii22-ii22

2023

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IL-18 Receptors, Their Role in Ligand Binding and Function: Anti-IL-1RAcPL Antibody, a Potent Antagonist of IL-18

The Journal of immunology (1950), 2000-11, Vol.165 (9), p.4950-4956

2000

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A phage display selected fab fragment with MHC class I-restricted specificity for MAGE-A1 allows for retargeting of primary human T lymphocytes

Gene therapy, 2001-11, Vol.8 (21), p.1601-1608

2001

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Phoenix-ampho outperforms PG13 as retroviral packaging cells to transduce human T cells with tumor-specific receptors: implications for clinical immunogene therapy of cancer

Cancer gene therapy, 2006-05, Vol.13 (5), p.503-509

2006

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Parallel detection of transduced T lymphocytes after immunogene therapy of renal cell cancer by flow cytometry and real-time polymerase chain reaction : Implications for loss of transgene expression

Human gene therapy, 2005-12, Vol.16 (12), p.1452-1462

2005

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In contrast to other soft tissue sarcomas, GIST shows enhanced numbers of immune checkpoint-negative CD8 T cells

European journal of cancer (1990), 2019-03, Vol.110, p.S9-S9

2019

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1863P Incidence and predictors of severe adverse events during anti-PD-1 treatment

Annals of oncology, 2021-09, Vol.32, p.S1251-S1252

2021

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B-cell clusters in the stroma at invasive tumour margin provide prognostic value in early-Stage oral-tongue cancer patients: The discovery and validation study

Annals of oncology, 2019-12, Vol.30, p.xi51

2019

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P1.09-21 Tumor Responses Based on Tumor Growth Rate During PD-1 Inhibitor Therapy in Advanced Non-Small-Cell Lung Cancer Patients

Journal of thoracic oncology, 2019-10, Vol.14 (10), p.S504-S504

2019

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860P The IOpener study: Tyrosine kinase activity in peripheral lymphocytes to predict durable response to immune checkpoint inhibition in patients with advanced melanoma

Annals of oncology, 2022-09, Vol.33, p.S943

2022

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Targeting melanoma with immunoliposomes coupled to anti-MAGE A1 TCR-like single-chain antibody

International journal of nanomedicine, 2016-01, Vol.11 (Issue 1), p.955-975

2016

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Adoptive therapy with TCR gene-engineered T cells to treat patients with MAGE-C2-positive melanoma and head and neck cancer

Cytotherapy (Oxford, England), 2020-05, Vol.22 (5), p.S128-S128

2020

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Retroviral vectors for clinical immunogene therapy are stable for up to 9 years

Cancer gene therapy, 2008-04, Vol.15 (4), p.268-274

2008

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1128P Germline variation in PDCD1 is associated with survival in metastatic melanoma after anti-PD-1 monotherapy

Annals of oncology, 2020-09, Vol.31, p.S758-S758

2020

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Breast cancer genomics and immuno-oncological markers to guide immune therapies

Intra-tumoral production of IL18, but not IL12, by TCR-engineered T cells is non-toxic and counteracts immune evasion of solid tumors

B-cell clusters at the invasive margin associate with longer survival in early-stage oral-tongue cancer patients

Case Report: Adequate T and B Cell Responses in a SARS-CoV-2 Infected Patient After Immune Checkpoint Inhibition

Two novel IL-1 family members, IL-1 delta and IL-1 epsilon, function as an antagonist and agonist of NF-kappa B activation through the orphan IL-1 receptor-related protein 2

GMP protocol to gene-engineer and process human T-cells revisited: medium critically determines yield, function and differentiation state of CD8+ T-cells

A critical role for interleukin 18 in primary and memory effector responses to Listeria monocytogenes that extends beyond its effects on Interferon gamma production

Redirecting human CD4 T lymphocytes to the MHC class I-restricted melanoma antigen MAGE-A1 by TCR αβ gene transfer requires CD8α

Cytokine Networking in Lungs of Immunocompetent Mice in Response to Inhaled Aspergillus fumigatus

999P NPC patients with post-RT EBV clearance show a higher frequency of peripheral CD8 T-cells expressing chemo-attractant receptors at baseline and during radiation therapy

OS10.5.A PERIVASCULAR CONTAINED T CELLS IN IDH-MUTANT ASTROCYTOMA CO-LOCALIZE WITH GEMISTOCYTIC TUMOR CELLS OF AN ASTROCYTE-STATE AND MACROPHAGES WITH AN IMMUNE-STIMULATORY PHENOTYPE

IL-18 Receptors, Their Role in Ligand Binding and Function: Anti-IL-1RAcPL Antibody, a Potent Antagonist of IL-18

A phage display selected fab fragment with MHC class I-restricted specificity for MAGE-A1 allows for retargeting of primary human T lymphocytes

Phoenix-ampho outperforms PG13 as retroviral packaging cells to transduce human T cells with tumor-specific receptors: implications for clinical immunogene therapy of cancer

Parallel detection of transduced T lymphocytes after immunogene therapy of renal cell cancer by flow cytometry and real-time polymerase chain reaction : Implications for loss of transgene expression

In contrast to other soft tissue sarcomas, GIST shows enhanced numbers of immune checkpoint-negative CD8 T cells

1863P Incidence and predictors of severe adverse events during anti-PD-1 treatment

B-cell clusters in the stroma at invasive tumour margin provide prognostic value in early-Stage oral-tongue cancer patients: The discovery and validation study

P1.09-21 Tumor Responses Based on Tumor Growth Rate During PD-1 Inhibitor Therapy in Advanced Non-Small-Cell Lung Cancer Patients

860P The IOpener study: Tyrosine kinase activity in peripheral lymphocytes to predict durable response to immune checkpoint inhibition in patients with advanced melanoma

Targeting melanoma with immunoliposomes coupled to anti-MAGE A1 TCR-like single-chain antibody

How Sensitive Are Ecosystem Services in European Forest Landscapes to Silvicultural Treatment?

Adoptive therapy with TCR gene-engineered T cells to treat patients with MAGE-C2-positive melanoma and head and neck cancer

Retroviral vectors for clinical immunogene therapy are stable for up to 9 years

1128P Germline variation in PDCD1 is associated with survival in metastatic melanoma after anti-PD-1 monotherapy

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