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Interaction of designed cationic antimicrobial peptides with the outer membrane of gram-negative bacteria

Scientific reports, 2024-01, Vol.14 (1), p.1894-1894, Article 1894

2024

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Roles of Hydrophobicity and Charge Distribution of Cationic Antimicrobial Peptides in Peptide-Membrane Interactions

The Journal of biological chemistry, 2012-03, Vol.287 (10), p.7738-7745

2012

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Method to generate highly stable D-amino acid analogs of bioactive helical peptides using a mirror image of the entire PDB

Proceedings of the National Academy of Sciences - PNAS, 2018-02, Vol.115 (7), p.1505-1510

2018

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Detergent binding explains anomalous SDS-PAGE migration of membrane proteins

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (6), p.1760-1765

2009

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Uncoupling Amphipathicity and Hydrophobicity: Role of Charge Clustering in Membrane Interactions of Cationic Antimicrobial Peptides

Biochemistry (Easton), 2021-08, Vol.60 (34), p.2586-2592

2021

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Positive Charge Patterning and Hydrophobicity of Membrane-Active Antimicrobial Peptides as Determinants of Activity, Toxicity, and Pharmacokinetic Stability

Journal of medicinal chemistry, 2019-07, Vol.62 (13), p.6276-6286

2019

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The Human Mutation K237_V238del in a Putative Lipid Binding Motif within the V-ATPase a2 Isoform Suggests a Molecular Mechanism Underlying Cutis Laxa

International journal of molecular sciences, 2024-02, Vol.25 (4), p.2170

2024

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Acrylamide concentration determines the direction and magnitude of helical membrane protein gel shifts

Proceedings of the National Academy of Sciences - PNAS, 2013-09, Vol.110 (39), p.15668-15673

2013

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Activity of a novel antimicrobial peptide against Pseudomonas aeruginosa biofilms

Scientific reports, 2018-10, Vol.8 (1), p.14728-12, Article 14728

2018

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Correction factors for membrane protein molecular weight readouts on sodium dodecyl sulfate–polyacrylamide gel electrophoresis

Analytical biochemistry, 2013-03, Vol.434 (1), p.67-72

2013

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Basis for Selectivity of Cationic Antimicrobial Peptides for Bacterial Versus Mammalian Membranes

The Journal of biological chemistry, 2005-10, Vol.280 (40), p.33960-33967

2005

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Characterization of a PIP Binding Site in the N-Terminal Domain of V-ATPase a4 and Its Role in Plasma Membrane Association

International journal of molecular sciences, 2023-03, Vol.24 (5), p.4867

2023

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Anti-Infectives Restore ORKAMBI ® Rescue of F508del-CFTR Function in Human Bronchial Epithelial Cells Infected with Clinical Strains of P. aeruginosa

Biomolecules (Basel, Switzerland), 2020-02, Vol.10 (2), p.334

2020

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Helix-Helix Interactions: Is the Medium the Message?

Structure (London), 2015-03, Vol.23 (3), p.437-438

2015

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Enhanced proteolytic resistance of cationic antimicrobial peptides through lysine side chain analogs and cyclization

Biochemical and biophysical research communications, 2022-07, Vol.612, p.105-109

2022

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Drug Efflux by a Small Multidrug Resistance Protein Is Inhibited by a Transmembrane Peptide

Antimicrobial Agents and Chemotherapy, 2012-07, Vol.56 (7), p.3911-3916

2012

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Design and characterization of a membrane protein unfolding platform in lipid bilayers

PloS one, 2015-03, Vol.10 (3), p.e0120253-e0120253

2015

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The structure of "unstructured" regions in peptides and proteins: Role of the polyproline II helix in protein folding and recognition

Biopolymers, 2005, Vol.80 (2-3), p.179-185

2005

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Membrane interactions of designed cationic antimicrobial peptides: The two thresholds

Biopolymers, 2008-05, Vol.89 (5), p.360-371

2008

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Cationic Hydrophobic Peptides with Antimicrobial Activity

Antimicrobial Agents and Chemotherapy, 2002-11, Vol.46 (11), p.3585-3590

2002

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Therapeutic design of peptide modulators of protein-protein interactions in membranes

Biochimica et biophysica acta. Biomembranes, 2017-04, Vol.1859 (4), p.577-585

2017

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Structure of the EmrE multidrug transporter and its use for inhibitor peptide design

Proceedings of the National Academy of Sciences - PNAS, 2018-08, Vol.115 (34), p.E7932-E7941

2018

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Congenital heart block maternal sera autoantibodies target an extracellular epitope on the α1G T-type calcium channel in human fetal hearts

PloS one, 2013-09, Vol.8 (9), p.e72668-e72668

2013

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Hydrophobic moment drives penetration of bacterial membranes by transmembrane peptides

The Journal of biological chemistry, 2023-11, Vol.299 (11), p.105266-105266, Article 105266

2023

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Heat treatment of thioredoxin fusions increases the purity of α‐helical transmembrane protein constructs

Protein science, 2021-09, Vol.30 (9), p.1974-1982

2021

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Interaction of designed cationic antimicrobial peptides with the outer membrane of gram-negative bacteria

Roles of Hydrophobicity and Charge Distribution of Cationic Antimicrobial Peptides in Peptide-Membrane Interactions

Method to generate highly stable D-amino acid analogs of bioactive helical peptides using a mirror image of the entire PDB

Detergent binding explains anomalous SDS-PAGE migration of membrane proteins

Uncoupling Amphipathicity and Hydrophobicity: Role of Charge Clustering in Membrane Interactions of Cationic Antimicrobial Peptides

Positive Charge Patterning and Hydrophobicity of Membrane-Active Antimicrobial Peptides as Determinants of Activity, Toxicity, and Pharmacokinetic Stability

The Human Mutation K237_V238del in a Putative Lipid Binding Motif within the V-ATPase a2 Isoform Suggests a Molecular Mechanism Underlying Cutis Laxa

Acrylamide concentration determines the direction and magnitude of helical membrane protein gel shifts

Activity of a novel antimicrobial peptide against Pseudomonas aeruginosa biofilms

Correction factors for membrane protein molecular weight readouts on sodium dodecyl sulfate–polyacrylamide gel electrophoresis

Basis for Selectivity of Cationic Antimicrobial Peptides for Bacterial Versus Mammalian Membranes

Characterization of a PIP Binding Site in the N-Terminal Domain of V-ATPase a4 and Its Role in Plasma Membrane Association

Anti-Infectives Restore ORKAMBI ® Rescue of F508del-CFTR Function in Human Bronchial Epithelial Cells Infected with Clinical Strains of P. aeruginosa

Helix-Helix Interactions: Is the Medium the Message?

Enhanced proteolytic resistance of cationic antimicrobial peptides through lysine side chain analogs and cyclization

Drug Efflux by a Small Multidrug Resistance Protein Is Inhibited by a Transmembrane Peptide

Design and characterization of a membrane protein unfolding platform in lipid bilayers

The structure of "unstructured" regions in peptides and proteins: Role of the polyproline II helix in protein folding and recognition

Membrane interactions of designed cationic antimicrobial peptides: The two thresholds

Cationic Hydrophobic Peptides with Antimicrobial Activity

Therapeutic design of peptide modulators of protein-protein interactions in membranes

Structure of the EmrE multidrug transporter and its use for inhibitor peptide design

Congenital heart block maternal sera autoantibodies target an extracellular epitope on the α1G T-type calcium channel in human fetal hearts

Hydrophobic moment drives penetration of bacterial membranes by transmembrane peptides

Heat treatment of thioredoxin fusions increases the purity of α‐helical transmembrane protein constructs

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