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Links between DNA Replication, Stem Cells and Cancer

Genes, 2017-01, Vol.8 (2), p.45

2017

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PIP5K1C phosphoinositide kinase deficiency distinguishes PIKFYVE-dependent cancer cells from non-malignant cells

Autophagy, 2023-09, Vol.19 (9), p.2464-2484

2023

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Cell Death and the p53 Enigma During Mammalian Embryonic Development

Stem cells (Dayton, Ohio), 2022-03, Vol.40 (3), p.227-238

2022

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Selective Killing of Cancer Cells by Suppression of Geminin Activity

Cancer research (Chicago, Ill.), 2009-06, Vol.69 (11), p.4870-4877

2009

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TEAD4 establishes the energy homeostasis essential for blastocoel formation

Development (Cambridge), 2013-09, Vol.140 (17), p.3680-3690

2013

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PIKFYVE inhibitors trigger interleukin‐24‐dependent cell death of autophagy‐dependent melanoma

Molecular oncology, 2024-04, Vol.18 (4), p.988-1011

2024

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A family of PIKFYVE inhibitors with therapeutic potential against autophagy-dependent cancer cells disrupt multiple events in lysosome homeostasis

Autophagy, 2019-10, Vol.15 (10), p.1694-1718

2019

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Efficacy of a small molecule inhibitor of the transcriptional cofactor PC4 in prevention and treatment of non-small cell lung cancer

PloS one, 2020-03, Vol.15 (3), p.e0230670-e0230670

2020

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Selective Termination of Autophagy-Dependent Cancers

Cells (Basel, Switzerland), 2024-06, Vol.13 (13), p.1096

2024

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Cell cycle arrest and apoptosis are not dependent on p53 prior to p53-dependent embryonic stem cell differentiation

Stem cells (Dayton, Ohio), 2020-09, Vol.38 (9), p.1091-1106

2020

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Cytoplasmic localization of p21 protects trophoblast giant cells from DNA damage induced apoptosis

PloS one, 2014-05, Vol.9 (5), p.e97434-e97434

2014

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DHS (trans−4,4′-dihydroxystilbene) suppresses DNA replication and tumor growth by inhibiting RRM2 (ribonucleotide reductase regulatory subunit M2)

Oncogene, 2018-12, Vol.38 (13), p.2364-2379

2018

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Transcription factor TEAD4 specifies the trophectoderm lineage at the beginning of mammalian development

Development (Cambridge), 2007-11, Vol.134 (21), p.3827-3836

2007

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Endoreplication

Cold Spring Harbor perspectives in biology, 2013-01, Vol.5 (1), p.a012948-a012948

2013

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Cell cycle arrest and apoptosis are not dependent on p53 prior to p53‐dependent embryonic stem cell differentiation

Stem cells (Dayton, Ohio), 2020-09, Vol.38 (9), p.1091-1106

2020

Volltextzugriff (PDF)

DHS (trans-4,4'-dihydroxystilbene) suppresses DNA replication and tumor growth by inhibiting RRM2 (ribonucleotide reductase regulatory subunit M2)

Oncogene, 2019-03, Vol.38 (13), p.2364-2379

2019

Volltextzugriff (PDF)

Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors

Nature communications, 2010-04, Vol.1 (1), p.9-9, Article 9

2010

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The Cdk2-c-Myc-miR-571 Axis Regulates DNA Replication and Genomic Stability by Targeting Geminin

Cancer research (Chicago, Ill.), 2019-10, Vol.79 (19), p.4896-4910

2019

Volltextzugriff (PDF)

Genome Duplication: The Heartbeat of Developing Organisms

Current topics in developmental biology, 2016, Vol.116, p.201

DePamphilis, Melvin L

2016

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Developmental Acquisition of p53 Functions

Genes, 2021-10, Vol.12 (11), p.1675

2021

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Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors

Nature communications, 2010-04, Vol.1 (1), p.1-12

2010

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Differentiation of trophoblast stem cells into giant cells is triggered by p57/Kip2 inhibition of CDK1 activity

Genes & development, 2008-11, Vol.22 (21), p.3024-3036

2008

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Checkpoint Kinase 1 Prevents Cell Cycle Exit Linked to Terminal Cell Differentiation

Molecular and Cellular Biology, 2011-10, Vol.31 (19), p.4129-4143

2011

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Cip/Kip cyclin-dependent protein kinase inhibitors and the road to polyploidy

Cell division, 2009-06, Vol.4 (1), p.10-10, Article 10

2009

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Cell Cycle Dependent Regulation of the Origin Recognition Complex

Cell cycle (Georgetown, Tex.), 2005-01, Vol.4 (1), p.70-79

DePamphilis, Melvin L.

2005

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Links between DNA Replication, Stem Cells and Cancer

PIP5K1C phosphoinositide kinase deficiency distinguishes PIKFYVE-dependent cancer cells from non-malignant cells

Cell Death and the p53 Enigma During Mammalian Embryonic Development

Selective Killing of Cancer Cells by Suppression of Geminin Activity

TEAD4 establishes the energy homeostasis essential for blastocoel formation

PIKFYVE inhibitors trigger interleukin‐24‐dependent cell death of autophagy‐dependent melanoma

A family of PIKFYVE inhibitors with therapeutic potential against autophagy-dependent cancer cells disrupt multiple events in lysosome homeostasis

Efficacy of a small molecule inhibitor of the transcriptional cofactor PC4 in prevention and treatment of non-small cell lung cancer

Selective Termination of Autophagy-Dependent Cancers

Cell cycle arrest and apoptosis are not dependent on p53 prior to p53-dependent embryonic stem cell differentiation

Cytoplasmic localization of p21 protects trophoblast giant cells from DNA damage induced apoptosis

DHS (trans−4,4′-dihydroxystilbene) suppresses DNA replication and tumor growth by inhibiting RRM2 (ribonucleotide reductase regulatory subunit M2)

Transcription factor TEAD4 specifies the trophectoderm lineage at the beginning of mammalian development

Endoreplication

Cell cycle arrest and apoptosis are not dependent on p53 prior to p53‐dependent embryonic stem cell differentiation

DHS (trans-4,4'-dihydroxystilbene) suppresses DNA replication and tumor growth by inhibiting RRM2 (ribonucleotide reductase regulatory subunit M2)

Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors

The Cdk2-c-Myc-miR-571 Axis Regulates DNA Replication and Genomic Stability by Targeting Geminin

Genome Duplication: The Heartbeat of Developing Organisms

Developmental Acquisition of p53 Functions

Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors

Differentiation of trophoblast stem cells into giant cells is triggered by p57/Kip2 inhibition of CDK1 activity

Checkpoint Kinase 1 Prevents Cell Cycle Exit Linked to Terminal Cell Differentiation

Cip/Kip cyclin-dependent protein kinase inhibitors and the road to polyploidy

Cell Cycle Dependent Regulation of the Origin Recognition Complex

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