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Inhibition of complement C5 protects against organ failure and reduces mortality in a baboon model of Escherichia coli sepsis

Proceedings of the National Academy of Sciences - PNAS, 2017-08, Vol.114 (31), p.E6390-E6399

2017

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AAV2-hAADC (Eladocagene Exuparvovec) Biodistribution and Expression: Superiority of Intraputaminal versus Intracerebroventricular and Intrathecal (Lumbar) Routes of Administration

International journal of toxicology, 2023-03, Vol.42 (2), p.135-145

2023

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Peptidomimetic Antibiotics Target Outer-Membrane Biogenesis in Pseudomonas aeruginosa

Science (American Association for the Advancement of Science), 2010-02, Vol.327 (5968), p.1010-1013

2010

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Plasma Membrane Ca2+ ATPase Isoform 2b Interacts Preferentially with Na+/H+ Exchanger Regulatory Factor 2 in Apical Plasma Membranes

The Journal of biological chemistry, 2002-03, Vol.277 (12), p.10506-10511

2002

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Discovery of novel, highly potent and selective β-hairpin mimetic CXCR4 inhibitors with excellent anti-HIV activity and pharmacokinetic profiles

Bioorganic & medicinal chemistry, 2006-12, Vol.14 (24), p.8396-8404

2006

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Cell-specific expression of plasma membrane calcium ATPase isoforms in retinal neurons

Journal of comparative neurology (1911), 2002-09, Vol.451 (1), p.1-21

2002

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Bradykinin and ATP Accelerate Ca2+ Efflux from Rat Sensory Neurons via Protein Kinase C and the Plasma Membrane Ca2+ Pump Isoform 4

Neuron (Cambridge, Mass.), 2002-01, Vol.33 (1), p.113-122

2002

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Plasma Membrane Ca2+-ATPase Isoforms 2b and 4b Interact Promiscuously and Selectively with Members of the Membrane-associated Guanylate Kinase Family of PDZ (PSD95/Dlg/ZO-1) Domain-containing Proteins

The Journal of biological chemistry, 2001-06, Vol.276 (24), p.21594-21600

2001

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Bradykinin and ATP accelerate Ca(2+) efflux from rat sensory neurons via protein kinase C and the plasma membrane Ca(2+) pump isoform 4

Neuron (Cambridge, Mass.), 2002-01, Vol.33 (1), p.113-122

2002

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Development of peptide therapeutics: A nonclinical safety assessment perspective

Regulatory toxicology and pharmacology, 2020-11, Vol.117, p.104766, Article 104766

2020

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Preclinical studies of gene replacement therapy for CDKL5 deficiency disorder

Molecular therapy, 2024-10, Vol.32 (10), p.3331-3345

2024

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Plasma Membrane Ca2+ ATPase Isoform 4b Binds to Membrane-associated Guanylate Kinase (MAGUK) Proteins via Their PDZ (PSD-95/Dlg/ZO-1) Domains

The Journal of biological chemistry, 1998-01, Vol.273 (3), p.1591-1595

1998

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RA101495, A Subcutaneously Administered Peptide Inhibitor of Complement Component 5 (C5) for the Treatment of Generalized Myasthenia Gravis (gMG): Phase 1 Results and Phase 2 Design (S31.006)

Neurology, 2018-04, Vol.90 (15_supplement)

2018

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Characterization of PISP, a Novel Single-PDZ Protein That Binds to All Plasma Membrane Ca2+-ATPase b-Splice Variants

Annals of the New York Academy of Sciences, 2003-04, Vol.986 (1), p.461-471

2003

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A Novel C5 Complement Inhibitor Protects Against Sepsis-Induced Activation of Complement, Coagulation and Inflammation and Provides Survival Benefit in E. coli Sepsis

Blood, 2014-12, Vol.124 (21), p.112-112

2014

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Complement C5 Inhibition Blocks the Cytokine Storm and Consumptive Coagulopathy By Decreasing Lipopolysaccharide (LPS) Release in E. coli Sepsis

Blood, 2015-12, Vol.126 (23), p.765-765

2015

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Preclinical Evaluation of RA101495, a Potent Cyclic Peptide Inhibitor of C5 for the Treatment of Paroxysmal Nocturnal Hemoglobinuria

Blood, 2015-12, Vol.126 (23), p.939-939

2015

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Development of RA101348, a Potent Cyclic Peptide Inhibitor of C5 for Complement-Mediated Diseases

Blood, 2014-12, Vol.124 (21), p.2936-2936

2014

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Abstract LB-304: ATSP-9172, a novel Stapled Peptide inhibitor of HIF-dependent transcriptional activity with in vivo antitumor efficacy in a preclinical model of prostate cancer

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.LB-304-LB-304

2013

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Discovery of Highly Potent and Selective CXCR4 Inhibitors Using Protein Epitope Mimetics (PEM) Technology

Chimia, 2007-04, Vol.61 (4), p.147

2007

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Characterization of PISP, a Novel Single‐PDZ Protein That Binds to All Plasma Membrane Ca 2+ ‐ATPase b‐Splice Variants

Annals of the New York Academy of Sciences, 2003-04, Vol.986 (1), p.461-471

2003

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Bradykinin and ATP Accelerate Ca 2+ Efflux from Rat Sensory Neurons via Protein Kinase C and the Plasma Membrane Ca 2+ Pump Isoform 4

Neuron (Cambridge, Mass.), 2002, Vol.33 (1), p.113-122

2002

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Primary structure of human plasma membrane Ca2+-ATPase isoform 3

Biochimica et biophysica acta. Biomembranes, 1996-08, Vol.1283 (1), p.10-13

1996

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Primary structure of human plasma membrane Ca 2+-ATPase isoform 3

Biochimica et biophysica acta. Biomembranes, 1996, Vol.1283 (1), p.10-13

1996

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mRNA expression of the four isoforms of the human plasma membrane Ca(2+)-ATPase in the human hippocampus

Brain research. Molecular brain research., 1997-04, Vol.45 (1), p.173-176

1997

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Inhibition of complement C5 protects against organ failure and reduces mortality in a baboon model of Escherichia coli sepsis

AAV2-hAADC (Eladocagene Exuparvovec) Biodistribution and Expression: Superiority of Intraputaminal versus Intracerebroventricular and Intrathecal (Lumbar) Routes of Administration

Peptidomimetic Antibiotics Target Outer-Membrane Biogenesis in Pseudomonas aeruginosa

Plasma Membrane Ca2+ ATPase Isoform 2b Interacts Preferentially with Na+/H+ Exchanger Regulatory Factor 2 in Apical Plasma Membranes

Discovery of novel, highly potent and selective β-hairpin mimetic CXCR4 inhibitors with excellent anti-HIV activity and pharmacokinetic profiles

Cell-specific expression of plasma membrane calcium ATPase isoforms in retinal neurons

Bradykinin and ATP Accelerate Ca2+ Efflux from Rat Sensory Neurons via Protein Kinase C and the Plasma Membrane Ca2+ Pump Isoform 4

Plasma Membrane Ca2+-ATPase Isoforms 2b and 4b Interact Promiscuously and Selectively with Members of the Membrane-associated Guanylate Kinase Family of PDZ (PSD95/Dlg/ZO-1) Domain-containing Proteins

Bradykinin and ATP accelerate Ca(2+) efflux from rat sensory neurons via protein kinase C and the plasma membrane Ca(2+) pump isoform 4

Development of peptide therapeutics: A nonclinical safety assessment perspective

Preclinical studies of gene replacement therapy for CDKL5 deficiency disorder

Plasma Membrane Ca2+ ATPase Isoform 4b Binds to Membrane-associated Guanylate Kinase (MAGUK) Proteins via Their PDZ (PSD-95/Dlg/ZO-1) Domains

RA101495, A Subcutaneously Administered Peptide Inhibitor of Complement Component 5 (C5) for the Treatment of Generalized Myasthenia Gravis (gMG): Phase 1 Results and Phase 2 Design (S31.006)

Characterization of PISP, a Novel Single-PDZ Protein That Binds to All Plasma Membrane Ca2+-ATPase b-Splice Variants

A Novel C5 Complement Inhibitor Protects Against Sepsis-Induced Activation of Complement, Coagulation and Inflammation and Provides Survival Benefit in E. coli Sepsis

Complement C5 Inhibition Blocks the Cytokine Storm and Consumptive Coagulopathy By Decreasing Lipopolysaccharide (LPS) Release in E. coli Sepsis

Preclinical Evaluation of RA101495, a Potent Cyclic Peptide Inhibitor of C5 for the Treatment of Paroxysmal Nocturnal Hemoglobinuria

Development of RA101348, a Potent Cyclic Peptide Inhibitor of C5 for Complement-Mediated Diseases

Abstract LB-304: ATSP-9172, a novel Stapled Peptide inhibitor of HIF-dependent transcriptional activity with in vivo antitumor efficacy in a preclinical model of prostate cancer

Discovery of Highly Potent and Selective CXCR4 Inhibitors Using Protein Epitope Mimetics (PEM) Technology

Characterization of PISP, a Novel Single‐PDZ Protein That Binds to All Plasma Membrane Ca 2+ ‐ATPase b‐Splice Variants

Bradykinin and ATP Accelerate Ca 2+ Efflux from Rat Sensory Neurons via Protein Kinase C and the Plasma Membrane Ca 2+ Pump Isoform 4

Primary structure of human plasma membrane Ca2+-ATPase isoform 3

Primary structure of human plasma membrane Ca 2+-ATPase isoform 3

mRNA expression of the four isoforms of the human plasma membrane Ca(2+)-ATPase in the human hippocampus

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