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Unexpected formation of highly functionalized dihydropyrans via addition-cyclization reactions between dimethyl oxoglutaconate and α,β-unsaturated hydrazones

Tetrahedron letters, 2009-05, Vol.50 (20), p.2298-2300

2009

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Synthesis and antitumor activity of 10-propargyl-10-deazaaminopterin

Journal of medicinal chemistry, 1993-07, Vol.36 (15), p.2228-2231

1993

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Stabilized Analogs of Thymopentin. 1. 4,5-Ketomethylene Pseudopeptides

Journal of medicinal chemistry, 1997-07, Vol.40 (15), p.2386-2397

1997

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Synthesis and antifolate properties of 5,10-ethano-5,10-dideazaaminopterin

Journal of medicinal chemistry, 1992-01, Vol.35 (2), p.320-324

1992

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Stabilized Analogs of Thymopentin. 2. 1,2- and 3,4-Ketomethylene Pseudopeptides

Journal of medicinal chemistry, 1997-07, Vol.40 (15), p.2398-2406

1997

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Analogues of Methotrexate in Rheumatoid Arthritis. 1. Effects of 10-Deazaaminopterin Analogues on Type II Collagen-Induced Arthritis in Mice

Journal of medicinal chemistry, 1997-01, Vol.40 (3), p.370-376

1997

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Analogues of Methotrexate in Rheumatoid Arthritis. 2. Effects of 5-Deazaaminopterin, 5,10-Dideazaaminopterin, and Analogues on Type II Collagen-Induced Arthritis in Mice

Journal of medicinal chemistry, 1997-01, Vol.40 (3), p.377-384

1997

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Stabilized Analogs of Thymopentin. 3. Evaluation of Ketomethylene Pseudopeptides for Antiarthritic Properties

Journal of medicinal chemistry, 1997-07, Vol.40 (15), p.2407-2411

1997

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Synthesis and antifolate properties of 10-alkyl-5,10-dideaza analogs of methotrexate and tetrahydrofolic acid

Journal of medicinal chemistry, 1990-02, Vol.33 (2), p.673-677

1990

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Synthesis and antifolate properties of 9-alkyl-10-deazaminopterins

Journal of medicinal chemistry, 1990-01, Vol.33 (1), p.212-215

1990

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Synthesis and evaluation of 8,10-dideazatetrahydrofolic acid and derivatives

Heterocycles, 1993-05, Vol.35 (2), p.755-761

1993

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N-Substituent modulation of opiate agonist/antagonist activity in resolved 3-methyl-3-(m-hydroxyphenyl)piperidines

Journal of medicinal chemistry, 1986-04, Vol.29 (4), p.531-537

1986

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Effects of addition of a 2-methyl group to ethyl nipecotates (.beta.-meperidines) on receptor affinities and opiate agonist/antagonist activities

Journal of medicinal chemistry, 1988-10, Vol.31 (10), p.2015-2021

1988

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Antimicrobial activity of 8-deazafolic acid

Journal of medicinal chemistry, 1974-04, Vol.17 (4), p.470-471

1974

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Synthesis of methyl 14-methyl-cis-8-hexadecenoate and 14-methyl-cis-8-hexadecen-1-ol. Sex attractant of Trogoderma inclusum

Journal of organic chemistry, 1971-09, Vol.36 (19), p.2902-2903

1971

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THE SYNTHESIS OF 5-DIMETHYLAMINOINDOLE AND DERIVATIVES

Canadian journal of chemistry, 1966-02, Vol.44 (3), p.387-393

DeGraw, Joseph I

1966

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Synthesis and antifolate activity of 10-deazaminopterin

Journal of medicinal chemistry, 1974-05, Vol.17 (5), p.552-553

1974

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Convenient synthesis of 6-hydroxycoumarin

Journal of chemical and engineering data, 1969-10, Vol.14 (4), p.509-510

1969

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Synthesis of 5,10-dideazaminopterin

Journal of heterocyclic chemistry, 1986-01, Vol.23 (1), p.1-4

1986

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The Structures of Dehydrotremetone and Hydroxytremetone

Journal of organic chemistry, 1962-11, Vol.27 (11), p.3917-3919

1962

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The Synthesis and Pharmacological Action of Tremetone

Journal of medicinal chemistry, 1963-05, Vol.6 (3), p.315-319

1963

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New Analogs of Methotrexate in Cancer and Arthritis

Current medicinal chemistry, 1995-08, Vol.2 (2), p.630-653

1995

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Structure-activity studies of 3,4,5-trimethoxybenzamides. I. Variation of the amine function

Journal of medicinal chemistry, 1969-07, Vol.12 (4), p.715-717

1969

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2-Amino-4-hydroxy-6-arylaminoethylpteridines as potential antimalarial agents

Journal of medicinal chemistry, 1971-03, Vol.14 (3), p.206-210

1971

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Experimentally induced phenylketonuria. 4. Potential inhibitors of phenylalanine hydroxylase

Journal of medicinal chemistry, 1972-07, Vol.15 (7), p.781-781

1972

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Unexpected formation of highly functionalized dihydropyrans via addition-cyclization reactions between dimethyl oxoglutaconate and α,β-unsaturated hydrazones

Synthesis and antitumor activity of 10-propargyl-10-deazaaminopterin

Stabilized Analogs of Thymopentin. 1. 4,5-Ketomethylene Pseudopeptides

Synthesis and antifolate properties of 5,10-ethano-5,10-dideazaaminopterin

Stabilized Analogs of Thymopentin. 2. 1,2- and 3,4-Ketomethylene Pseudopeptides

Analogues of Methotrexate in Rheumatoid Arthritis. 1. Effects of 10-Deazaaminopterin Analogues on Type II Collagen-Induced Arthritis in Mice

Analogues of Methotrexate in Rheumatoid Arthritis. 2. Effects of 5-Deazaaminopterin, 5,10-Dideazaaminopterin, and Analogues on Type II Collagen-Induced Arthritis in Mice

Stabilized Analogs of Thymopentin. 3. Evaluation of Ketomethylene Pseudopeptides for Antiarthritic Properties

Synthesis and antifolate properties of 10-alkyl-5,10-dideaza analogs of methotrexate and tetrahydrofolic acid

Synthesis and antifolate properties of 9-alkyl-10-deazaminopterins

Synthesis and evaluation of 8,10-dideazatetrahydrofolic acid and derivatives

N-Substituent modulation of opiate agonist/antagonist activity in resolved 3-methyl-3-(m-hydroxyphenyl)piperidines

Effects of addition of a 2-methyl group to ethyl nipecotates (.beta.-meperidines) on receptor affinities and opiate agonist/antagonist activities

Antimicrobial activity of 8-deazafolic acid

Synthesis of methyl 14-methyl-cis-8-hexadecenoate and 14-methyl-cis-8-hexadecen-1-ol. Sex attractant of Trogoderma inclusum

THE SYNTHESIS OF 5-DIMETHYLAMINOINDOLE AND DERIVATIVES

Synthesis and antifolate activity of 10-deazaminopterin

Convenient synthesis of 6-hydroxycoumarin

Synthesis of 5,10-dideazaminopterin

The Structures of Dehydrotremetone and Hydroxytremetone

The Synthesis and Pharmacological Action of Tremetone

New Analogs of Methotrexate in Cancer and Arthritis

Structure-activity studies of 3,4,5-trimethoxybenzamides. I. Variation of the amine function

2-Amino-4-hydroxy-6-arylaminoethylpteridines as potential antimalarial agents

Experimentally induced phenylketonuria. 4. Potential inhibitors of phenylalanine hydroxylase

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