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Encorafenib plus binimetinib versus vemurafenib or encorafenib in patients with BRAF-mutant melanoma (COLUMBUS): a multicentre, open-label, randomised phase 3 trial

The lancet oncology, 2018-05, Vol.19 (5), p.603-615

2018

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Pomalidomide and lenalidomide regulate erythropoiesis and fetal hemoglobin production in human CD34+ cells

The Journal of clinical investigation, 2008-01, Vol.118 (1), p.248-258

2008

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Overall survival in patients with BRAF-mutant melanoma receiving encorafenib plus binimetinib versus vemurafenib or encorafenib (COLUMBUS): a multicentre, open-label, randomised, phase 3 trial

The lancet oncology, 2018-10, Vol.19 (10), p.1315-1327

2018

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Pomalidomide augments fetal hemoglobin production without the myelosuppressive effects of hydroxyurea in transgenic sickle cell mice

Blood, 2011-07, Vol.118 (4), p.1109-1112

2011

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Binding of Recombinant Feline Immunodeficiency Virus Surface Glycoprotein to Feline Cells: Role of CXCR4, Cell-Surface Heparans, and an Unidentified Non-CXCR4 Receptor

Journal of Virology, 2001-05, Vol.75 (10), p.4528-4539

2001

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Tumor lysis syndrome/tumor flare reaction in lenalidomide-treated chronic lymphocytic leukemia

Journal of clinical oncology, 2007-11, Vol.25 (31), p.5047-5047

2007

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Construction of SHIVs expressing quaternary neutralization epitopes in Env and mimicking the neutralization phenotype of typical HIV-1 isolates

Retrovirology, 2012-09, Vol.9 (S2), p.P28-P28, Article P28

2012

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Influence of ORF2 on Host Cell Tropism of Feline Immunodeficiency Virus

Virology (New York, N.Y.), 1996-01, Vol.215 (1), p.10-16

1996

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Demonstration that orf2 encodes the feline immunodeficiency virus transactivating (Tat) protein and characterization of a unique gene product with partial Rev activity

Journal of Virology, 1999-01, Vol.73 (1), p.608-617

1999

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Blocking of feline immunodeficiency virus infection by a monoclonal antibody to CD9 is via inhibition of virus release rather than interference with receptor binding

Journal of Virology, 1997-08, Vol.71 (8), p.5742-5749

1997

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Feline immunodeficiency virus targets activated CD4⁺ T cells by using CD134 as a binding receptor

Proceedings of the National Academy of Sciences - PNAS, 2004-08, Vol.101 (35), p.13044-13049

2004

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A Highly Conserved Arginine in gp120 Governs HIV-1 Binding to Both Syndecans and CCR5 via Sulfated Motifs

The Journal of biological chemistry, 2005-11, Vol.280 (47), p.39493-39504

2005

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Human Immunodeficiency Virus Envelope (gp120) Binding to DC-SIGN and Primary Dendritic Cells Is Carbohydrate Dependent but Does Not Involve 2G12 or Cyanovirin Binding Sites: Implications for Structural Analyses of gp120-DC-SIGN Binding

Journal of Virology, 2002-12, Vol.76 (24), p.12855-12865

2002

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Sequential CD134-CXCR4 Interactions in Feline Immunodeficiency Virus (FIV): Soluble CD134 Activates FIV Env for CXCR4-Dependent Entry and Reveals a Cryptic Neutralization Epitope

Journal of Virology, 2006-03, Vol.80 (6), p.3088-3091

2006

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Structural mapping of CD134 residues critical for interaction with feline immunodeficiency virus

Nature structural & molecular biology, 2005-01, Vol.12 (1), p.60-66

2005

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Molecular mechanisms of FIV infection

Veterinary immunology and immunopathology, 2008-05, Vol.123 (1), p.3-13

2008

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Adverse events of special interest in the phase 3 COLUMBUS study

Journal of clinical oncology, 2018-05, Vol.36 (15_suppl), p.9567-9567

2018

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Overall survival in COLUMBUS: A phase 3 trial of encorafenib (ENCO) plus binimetinib (BINI) vs vemurafenib (VEM) or enco in BRAF -mutant melanoma

Journal of clinical oncology, 2018-05, Vol.36 (15_suppl), p.9504-9504

2018

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Factors That Increase the Effective Concentration of CXCR4 Dictate Feline Immunodeficiency Virus Tropism and Kinetics of Replication

Journal of Virology, 2004-09, Vol.78 (17), p.9132-9143

2004

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Specific Interaction of Feline Immunodeficiency Virus Surface Glycoprotein with Human DC-SIGN

Journal of Virology, 2004-03, Vol.78 (5), p.2597-2600

2004

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Feline Immunodeficiency Virus OrfA Is Distinct from Other Lentivirus Transactivators

Journal of Virology, 2002-10, Vol.76 (19), p.9624-9634

2002

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A phase Ib/II study of BRAF inhibitor (BRAFi) encorafenib (ENCO) plus MEK inhibitor (MEKi) binimetinib (BINI) in cutaneous melanoma patients naive to BRAFi treatment

Journal of clinical oncology, 2015-05, Vol.33 (15_suppl), p.9007-9007

2015

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Modulation of cellular differentiation and cell fate for cancer therapy

Current opinion in investigational drugs (London, England : 2000), 2004-12, Vol.5 (12), p.1268

2004

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Initial results from a phase I, open-label, dose escalation study of the oral BRAF inhibitor LGX818 in patients with BRAF V600 mutant advanced or metastatic melanoma

Journal of clinical oncology, 2013-05, Vol.31 (15_suppl), p.9028-9028

2013

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Preliminary results from a phase Ib/II, open-label, dose-escalation study of the oral BRAF inhibitor LGX818 in combination with the oral MEK1/2 inhibitor MEK162 in BRAF V600-dependent advanced solid tumors

Journal of clinical oncology, 2013-05, Vol.31 (15_suppl), p.9029-9029

2013

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Encorafenib plus binimetinib versus vemurafenib or encorafenib in patients with BRAF-mutant melanoma (COLUMBUS): a multicentre, open-label, randomised phase 3 trial

Pomalidomide and lenalidomide regulate erythropoiesis and fetal hemoglobin production in human CD34+ cells

Overall survival in patients with BRAF-mutant melanoma receiving encorafenib plus binimetinib versus vemurafenib or encorafenib (COLUMBUS): a multicentre, open-label, randomised, phase 3 trial

Pomalidomide augments fetal hemoglobin production without the myelosuppressive effects of hydroxyurea in transgenic sickle cell mice

Binding of Recombinant Feline Immunodeficiency Virus Surface Glycoprotein to Feline Cells: Role of CXCR4, Cell-Surface Heparans, and an Unidentified Non-CXCR4 Receptor

Tumor lysis syndrome/tumor flare reaction in lenalidomide-treated chronic lymphocytic leukemia

Construction of SHIVs expressing quaternary neutralization epitopes in Env and mimicking the neutralization phenotype of typical HIV-1 isolates

Influence of ORF2 on Host Cell Tropism of Feline Immunodeficiency Virus

Demonstration that orf2 encodes the feline immunodeficiency virus transactivating (Tat) protein and characterization of a unique gene product with partial Rev activity

Blocking of feline immunodeficiency virus infection by a monoclonal antibody to CD9 is via inhibition of virus release rather than interference with receptor binding

Feline immunodeficiency virus targets activated CD4⁺ T cells by using CD134 as a binding receptor

A Highly Conserved Arginine in gp120 Governs HIV-1 Binding to Both Syndecans and CCR5 via Sulfated Motifs

Human Immunodeficiency Virus Envelope (gp120) Binding to DC-SIGN and Primary Dendritic Cells Is Carbohydrate Dependent but Does Not Involve 2G12 or Cyanovirin Binding Sites: Implications for Structural Analyses of gp120-DC-SIGN Binding

Sequential CD134-CXCR4 Interactions in Feline Immunodeficiency Virus (FIV): Soluble CD134 Activates FIV Env for CXCR4-Dependent Entry and Reveals a Cryptic Neutralization Epitope

Structural mapping of CD134 residues critical for interaction with feline immunodeficiency virus

Molecular mechanisms of FIV infection

Adverse events of special interest in the phase 3 COLUMBUS study

Overall survival in COLUMBUS: A phase 3 trial of encorafenib (ENCO) plus binimetinib (BINI) vs vemurafenib (VEM) or enco in BRAF -mutant melanoma

Factors That Increase the Effective Concentration of CXCR4 Dictate Feline Immunodeficiency Virus Tropism and Kinetics of Replication

Specific Interaction of Feline Immunodeficiency Virus Surface Glycoprotein with Human DC-SIGN

Feline Immunodeficiency Virus OrfA Is Distinct from Other Lentivirus Transactivators

A phase Ib/II study of BRAF inhibitor (BRAFi) encorafenib (ENCO) plus MEK inhibitor (MEKi) binimetinib (BINI) in cutaneous melanoma patients naive to BRAFi treatment

Modulation of cellular differentiation and cell fate for cancer therapy

Initial results from a phase I, open-label, dose escalation study of the oral BRAF inhibitor LGX818 in patients with BRAF V600 mutant advanced or metastatic melanoma

Preliminary results from a phase Ib/II, open-label, dose-escalation study of the oral BRAF inhibitor LGX818 in combination with the oral MEK1/2 inhibitor MEK162 in BRAF V600-dependent advanced solid tumors

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