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Scaffolds obtained from decellularized human extrahepatic bile ducts support organoids to establish functional biliary tissue in a dish

Biotechnology and bioengineering, 2021-02, Vol.118 (2), p.836-851

2021

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A functional CFTR assay using primary cystic fibrosis intestinal organoids

Nature medicine, 2013-07, Vol.19 (7), p.939-945

2013

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Cystic Fibrosis Related Liver Disease: Research Challenges and Future Perspectives

Journal of pediatric gastroenterology and nutrition, 2017-10, Vol.65 (4), p.443-448

2017

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Alterations of mucosa-attached microbiome and epithelial cell numbers in the cystic fibrosis small intestine with implications for intestinal disease

Scientific reports, 2022-04, Vol.12 (1), p.6593-6593, Article 6593

2022

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Mini-gut: a promising model for drug development

Drug discovery today, 2019-09, Vol.24 (9), p.1784-1794

2019

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Impact of hypoxia and AMPK on CFTR-mediated bicarbonate secretion in human cholangiocyte organoids

American journal of physiology: Gastrointestinal and liver physiology, 2021-05, Vol.320 (5), p.G741-G752

2021

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Human extrahepatic and intrahepatic cholangiocyte organoids show region-specific differentiation potential and model cystic fibrosis-related bile duct disease

Scientific reports, 2020-12, Vol.10 (1), p.21900-21900, Article 21900

2020

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Differential thermostability and response to cystic fibrosis transmembrane conductance regulator potentiators of human and mouse F508del-CFTR

American journal of physiology. Lung cellular and molecular physiology, 2019-07, Vol.317 (1), p.L71-L86

2019

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Rescue of murine F508del CFTR activity in native intestine by low temperature and proteasome inhibitors

PloS one, 2012-12, Vol.7 (12), p.e52070-e52070

2012

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Assessing cell-specific effects of genetic variations using tRNA microarrays

BMC genomics, 2019-07, Vol.20 (Suppl 8), p.549-549, Article 549

2019

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Mouse models of cystic fibrosis: Phenotypic analysis and research applications

Journal of cystic fibrosis, 2011-06, Vol.10, p.S152-S171

2011

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Cholic acid induces a Cftr dependent biliary secretion and liver growth response in mice

PloS one, 2015-02, Vol.10 (2), p.e0117599-e0117599

2015

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Pro-inflammatory cytokines stimulate CFTR-dependent anion secretion in pancreatic ductal epithelium

Cellular & molecular biology letters, 2024-01, Vol.29 (1), p.18-18, Article 18

2024

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Activation of Intestinal Cl− Secretion by Lubiprostone Requires the Cystic Fibrosis Transmembrane Conductance Regulator

Gastroenterology (New York, N.Y. 1943), 2009-09, Vol.137 (3), p.976-985

2009

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Folding of CFTR Is Predominantly Cotranslational

Molecular cell, 2005-10, Vol.20 (2), p.277-287

2005

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Human Enteroids/Colonoids and Intestinal Organoids Functionally Recapitulate Normal Intestinal Physiology and Pathophysiology

The Journal of biological chemistry, 2016-02, Vol.291 (8), p.3759-3766

2016

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A Potential Treatment of Congenital Sodium Diarrhea in Patients With Activating GUCY2C Mutations

Clinical and translational gastroenterology, 2021-11, Vol.12 (11), p.e00427-e00427

2021

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Lysophosphatidic Acid Stimulates the Intestinal Brush Border Na+ /H+ Exchanger 3 and Fluid Absorption via LPA5 and NHERF2

Gastroenterology (New York, N.Y. 1943), 2010-02, Vol.138 (2), p.649-658

2010

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Bicarbonate Transport in Cystic Fibrosis and Pancreatitis

Cells (Basel, Switzerland), 2021-12, Vol.11 (1), p.54

2021

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Compartmentalized Accumulation of cAMP near Complexes of Multidrug Resistance Protein 4 (MRP4) and Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Contributes to Drug-induced Diarrhea

The Journal of biological chemistry, 2015-05, Vol.290 (18), p.11246-11257

2015

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Semi-synthesis of a HGF/SF kringle one (K1) domain scaffold generates a potent in vivo MET receptor agonist

Chemical science (Cambridge), 2015-01, Vol.6 (3), p.2110-2121

2015

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Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice

The Journal of clinical investigation, 2009-03, Vol.119 (3), p.540-550

2009

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Theratyping of the Rare CFTR Variants E193K and R334W in Rectal Organoid-Derived Epithelial Monolayers

Journal of personalized medicine, 2022-04, Vol.12 (4), p.632

2022

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Human enteroids: preclinical models of non-inflammatory diarrhea

Stem cell research & therapy, 2013-12, Vol.4 Suppl 1 (S1), p.S3-S3, Article S3

2013

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Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis

Science translational medicine, 2016-06, Vol.8 (344), p.344ra84

2016

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Scaffolds obtained from decellularized human extrahepatic bile ducts support organoids to establish functional biliary tissue in a dish

A functional CFTR assay using primary cystic fibrosis intestinal organoids

Cystic Fibrosis Related Liver Disease: Research Challenges and Future Perspectives

Alterations of mucosa-attached microbiome and epithelial cell numbers in the cystic fibrosis small intestine with implications for intestinal disease

Mini-gut: a promising model for drug development

Impact of hypoxia and AMPK on CFTR-mediated bicarbonate secretion in human cholangiocyte organoids

Human extrahepatic and intrahepatic cholangiocyte organoids show region-specific differentiation potential and model cystic fibrosis-related bile duct disease

Differential thermostability and response to cystic fibrosis transmembrane conductance regulator potentiators of human and mouse F508del-CFTR

Rescue of murine F508del CFTR activity in native intestine by low temperature and proteasome inhibitors

Assessing cell-specific effects of genetic variations using tRNA microarrays

Mouse models of cystic fibrosis: Phenotypic analysis and research applications

Cholic acid induces a Cftr dependent biliary secretion and liver growth response in mice

Pro-inflammatory cytokines stimulate CFTR-dependent anion secretion in pancreatic ductal epithelium

Activation of Intestinal Cl− Secretion by Lubiprostone Requires the Cystic Fibrosis Transmembrane Conductance Regulator

Folding of CFTR Is Predominantly Cotranslational

Human Enteroids/Colonoids and Intestinal Organoids Functionally Recapitulate Normal Intestinal Physiology and Pathophysiology

A Potential Treatment of Congenital Sodium Diarrhea in Patients With Activating GUCY2C Mutations

Lysophosphatidic Acid Stimulates the Intestinal Brush Border Na+ /H+ Exchanger 3 and Fluid Absorption via LPA5 and NHERF2

Bicarbonate Transport in Cystic Fibrosis and Pancreatitis

Compartmentalized Accumulation of cAMP near Complexes of Multidrug Resistance Protein 4 (MRP4) and Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Contributes to Drug-induced Diarrhea

Semi-synthesis of a HGF/SF kringle one (K1) domain scaffold generates a potent in vivo MET receptor agonist

Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice

Theratyping of the Rare CFTR Variants E193K and R334W in Rectal Organoid-Derived Epithelial Monolayers

Human enteroids: preclinical models of non-inflammatory diarrhea

Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis

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