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Are reactive oxygen species still the basis for diabetic complications?

Clinical science (1979), 2015-07, Vol.129 (2), p.199-216

2015

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Nrf2 activators as attractive therapeutics for diabetic nephropathy

Diabetes (New York, N.Y.), 2011-11, Vol.60 (11), p.2683-2684

de Haan, Judy B

2011

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Ebselen by modulating oxidative stress improves hypoxia-induced macroglial Müller cell and vascular injury in the retina

Experimental eye research, 2015-07, Vol.136, p.1-8

2015

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A potent Nrf2 activator, dh404, bolsters antioxidant capacity in glial cells and attenuates ischaemic retinopathy

Clinical science (1979), 2016-08, Vol.130 (15), p.1375-1387

2016

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Oxidative Stress and NLRP3-Inflammasome Activity as Significant Drivers of Diabetic Cardiovascular Complications: Therapeutic Implications

Frontiers in physiology, 2018-02, Vol.9, p.114-114

2018

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Adverse renal effects of NLRP3 inflammasome inhibition by MCC950 in an interventional model of diabetic kidney disease

Clinical science (1979), 2022-01, Vol.136 (2), p.167-180

2022

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Dimethyl Fumarate and Its Esters: A Drug with Broad Clinical Utility?

Pharmaceuticals (Basel, Switzerland), 2020-10, Vol.13 (10), p.306

2020

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NADPH Oxidase 1 Plays a Key Role in Diabetes Mellitus–Accelerated Atherosclerosis

Circulation (New York, N.Y.), 2013-05, Vol.127 (18), p.1888-1902

2013

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Nrf2 Activation Is a Potential Therapeutic Approach to Attenuate Diabetic Retinopathy

Investigative ophthalmology & visual science, 2018-02, Vol.59 (2), p.815-825

2018

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Recent novel approaches to limit oxidative stress and inflammation in diabetic complications

Clinical & translational immunology, 2018, Vol.7 (4), p.e1016-n/a

2018

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Imatinib inhibits vascular smooth muscle proteoglycan synthesis and reduces LDL binding in vitro and aortic lipid deposition in vivo

Journal of cellular and molecular medicine, 2010-06, Vol.14 (6b), p.1408-1418

2010

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The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) activator dh404 protects against diabetes-induced endothelial dysfunction

Cardiovascular diabetology, 2017-03, Vol.16 (1), p.33-33, Article 33

2017

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Targeting Nrf2 for the treatment of Duchenne Muscular Dystrophy

Redox biology, 2021-01, Vol.38, p.101803, Article 101803

2021

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Direct Endothelial Nitric Oxide Synthase Activation Provides Atheroprotection in Diabetes-Accelerated Atherosclerosis

Diabetes (New York, N.Y.), 2015-11, Vol.64 (11), p.3937-3950

2015

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The Mechanisms of Restenosis and Relevance to Next Generation Stent Design

Biomolecules (Basel, Switzerland), 2022-03, Vol.12 (3), p.430

2022

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Cardiovascular characterisation of a novel mouse model that combines hypertension and diabetes co-morbidities

Scientific reports, 2023-05, Vol.13 (1), p.8741-8741

2023

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Plasmalogen modulation attenuates atherosclerosis in ApoE- and ApoE/GPx1-deficient mice

Atherosclerosis, 2015-12, Vol.243 (2), p.598-608

2015

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Translating atherosclerosis research from bench to bedside: navigating the barriers for effective preclinical drug discovery

Clinical science (1979), 2022-12, Vol.136 (23), p.1731-1758

2022

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Antiatherosclerotic and Renoprotective Effects of Ebselen in the Diabetic Apolipoprotein E/GPx1-Double Knockout Mouse

Diabetes (New York, N.Y.), 2010-12, Vol.59 (12), p.3198-3207

2010

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Highly active nisin coated polycaprolactone electrospun fibers against both Staphylococcus aureus and Pseudomonas aeruginosa

Biomaterials advances, 2023-11, Vol.154, p.213641, Article 213641

2023

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Derivative of Bardoxolone Methyl, dh404, in an Inverse Dose-Dependent Manner Lessens Diabetes-Associated Atherosclerosis and Improves Diabetic Kidney Disease

Diabetes (New York, N.Y.), 2014-09, Vol.63 (9), p.3091-3103

2014

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Lack of the antioxidant enzyme glutathione peroxidase-1 accelerates atherosclerosis in diabetic apolipoprotein E-deficient mice

Circulation (New York, N.Y.), 2007-04, Vol.115 (16), p.2178-2187

2007

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SOD2 in skeletal muscle: New insights from an inducible deletion model

Redox biology, 2021-11, Vol.47, p.102135-102135, Article 102135

2021

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Author Correction: Selenium–GPX4 axis protects follicular helper T cells from ferroptosis

Nature immunology, 2021-12, Vol.22 (12), p.1599-1599

2021

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The modified selenenyl amide, M-hydroxy ebselen, attenuates diabetic nephropathy and diabetes-associated atherosclerosis in ApoE/GPx1 double knockout mice

PloS one, 2013-07, Vol.8 (7), p.e69193-e69193

2013

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Are reactive oxygen species still the basis for diabetic complications?

Nrf2 activators as attractive therapeutics for diabetic nephropathy

Ebselen by modulating oxidative stress improves hypoxia-induced macroglial Müller cell and vascular injury in the retina

A potent Nrf2 activator, dh404, bolsters antioxidant capacity in glial cells and attenuates ischaemic retinopathy

Oxidative Stress and NLRP3-Inflammasome Activity as Significant Drivers of Diabetic Cardiovascular Complications: Therapeutic Implications

Adverse renal effects of NLRP3 inflammasome inhibition by MCC950 in an interventional model of diabetic kidney disease

Dimethyl Fumarate and Its Esters: A Drug with Broad Clinical Utility?

NADPH Oxidase 1 Plays a Key Role in Diabetes Mellitus–Accelerated Atherosclerosis

Nrf2 Activation Is a Potential Therapeutic Approach to Attenuate Diabetic Retinopathy

Recent novel approaches to limit oxidative stress and inflammation in diabetic complications

Imatinib inhibits vascular smooth muscle proteoglycan synthesis and reduces LDL binding in vitro and aortic lipid deposition in vivo

The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) activator dh404 protects against diabetes-induced endothelial dysfunction

Targeting Nrf2 for the treatment of Duchenne Muscular Dystrophy

Direct Endothelial Nitric Oxide Synthase Activation Provides Atheroprotection in Diabetes-Accelerated Atherosclerosis

The Mechanisms of Restenosis and Relevance to Next Generation Stent Design

Cardiovascular characterisation of a novel mouse model that combines hypertension and diabetes co-morbidities

Plasmalogen modulation attenuates atherosclerosis in ApoE- and ApoE/GPx1-deficient mice

Translating atherosclerosis research from bench to bedside: navigating the barriers for effective preclinical drug discovery

Antiatherosclerotic and Renoprotective Effects of Ebselen in the Diabetic Apolipoprotein E/GPx1-Double Knockout Mouse

Highly active nisin coated polycaprolactone electrospun fibers against both Staphylococcus aureus and Pseudomonas aeruginosa

Derivative of Bardoxolone Methyl, dh404, in an Inverse Dose-Dependent Manner Lessens Diabetes-Associated Atherosclerosis and Improves Diabetic Kidney Disease

Lack of the antioxidant enzyme glutathione peroxidase-1 accelerates atherosclerosis in diabetic apolipoprotein E-deficient mice

SOD2 in skeletal muscle: New insights from an inducible deletion model

Author Correction: Selenium–GPX4 axis protects follicular helper T cells from ferroptosis

The modified selenenyl amide, M-hydroxy ebselen, attenuates diabetic nephropathy and diabetes-associated atherosclerosis in ApoE/GPx1 double knockout mice

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