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The BET Family of Proteins Targets Moloney Murine Leukemia Virus Integration near Transcription Start Sites

Cell reports (Cambridge), 2013-11, Vol.5 (4), p.886-894

2013

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LEDGF/p75-independent HIV-1 replication demonstrates a role for HRP-2 and remains sensitive to inhibition by LEDGINs

PLoS pathogens, 2012-03, Vol.8 (3), p.e1002558

2012

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Correction: LEDGF/p75-Independent HIV-1 Replication Demonstrates a Role for HRP-2 and Remains Sensitive to Inhibition by LEDGINs

PLoS pathogens, 2020-09, Vol.16 (9), p.e1008894-e1008894

2020

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Virus evolution reveals an exclusive role for LEDGF/p75 in chromosomal tethering of HIV

PLoS pathogens, 2007-03, Vol.3 (3), p.e47

2007

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A ubiquitous disordered protein interaction module orchestrates transcription elongation

Science (American Association for the Advancement of Science), 2021-11, Vol.374 (6571), p.1113-1121

2021

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HIV-1 Integrase Variants Retarget Viral Integration and Are Associated with Disease Progression in a Chronic Infection Cohort

Cell host & microbe, 2014-11, Vol.16 (5), p.651-662

2014

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LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions

Retrovirology, 2013-05, Vol.10 (1), p.57-57, Article 57

2013

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Correction: Y-box-binding protein 1 supports the early and late steps of HIV replication

PloS one, 2020-10, Vol.15 (10), p.e0241893-e0241893

2020

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Targeting Virus-host Interactions of HIV Replication

Current topics in medicinal chemistry, 2016-01, Vol.16 (10), p.1167-1190

2016

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Validation and structural characterization of the LEDGF/p75-MLL interface as a new target for the treatment of MLL-dependent leukemia

Cancer research (Chicago, Ill.), 2014-09, Vol.74 (18), p.5139-5151

2014

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Transient and Stable Knockdown of the Integrase Cofactor LEDGF/p75 Reveals Its Role in the Replication Cycle of Human Immunodeficiency Virus

Journal of Virology, 2006-02, Vol.80 (4), p.1886-1896

2006

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Overexpression of the Lens Epithelium-Derived Growth Factor/p75 Integrase Binding Domain Inhibits Human Immunodeficiency Virus Replication

Journal of Virology, 2006-12, Vol.80 (23), p.11498-11509

2006

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Y-box-binding protein 1 supports the early and late steps of HIV replication

PloS one, 2018-07, Vol.13 (7), p.e0200080

2018

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Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif

Nature communications, 2015-08, Vol.6 (1), p.7968-7968, Article 7968

2015

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Retroviral integration: Site matters

BioEssays, 2015-11, Vol.37 (11), p.1202-1214

2015

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HRP-2 determines HIV-1 integration site selection in LEDGF/p75 depleted cells

Retrovirology, 2012-10, Vol.9 (1), p.84-84, Article 84

2012

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Correction to: HIV-1 IN/Pol recruits LEDGF/p75 into viral particles

Retrovirology, 2020-07, Vol.17 (1), p.1-23, Article 23

2020

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Lens Epithelium-derived Growth Factor/p75 Interacts with the Transposase-derived DDE Domain of PogZ

The Journal of biological chemistry, 2009-04, Vol.284 (17), p.11467-11477

2009

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BET-Independent Murine Leukemia Virus Integration Is Retargeted In Vivo and Selects Distinct Genomic Elements for Lymphomagenesis

Microbiology spectrum, 2022-08, Vol.10 (4), p.e0147822-e0147822

2022

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Correction to: LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions

Retrovirology, 2020-07, Vol.17 (1), p.1-22, Article 22

2020

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BET-independent MLV-based Vectors Target Away From Promoters and Regulatory Elements

Molecular therapy. Nucleic acids, 2014-07, Vol.3 (7), p.e179-e179, Article e179

2014

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Impact of the Central Polypurine Tract on the Kinetics of Human Immunodeficiency Virus Type 1 Vector Transduction

Journal of Virology, 2003-04, Vol.77 (8), p.4685-4694

2003

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Engineering Next-Generation BET-Independent MLV Vectors for Safer Gene Therapy

Molecular therapy. Nucleic acids, 2017-06, Vol.7 (C), p.231-245

2017

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Unlike Its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival

Cells (Basel, Switzerland), 2021-01, Vol.10 (1), p.192

2021

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The BET Family of Proteins Targets Moloney Murine Leukemia Virus Integration near Transcription Start Sites

LEDGF/p75-independent HIV-1 replication demonstrates a role for HRP-2 and remains sensitive to inhibition by LEDGINs

Correction: LEDGF/p75-Independent HIV-1 Replication Demonstrates a Role for HRP-2 and Remains Sensitive to Inhibition by LEDGINs

Virus evolution reveals an exclusive role for LEDGF/p75 in chromosomal tethering of HIV

A ubiquitous disordered protein interaction module orchestrates transcription elongation

HIV-1 Integrase Variants Retarget Viral Integration and Are Associated with Disease Progression in a Chronic Infection Cohort

LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions

Correction: Y-box-binding protein 1 supports the early and late steps of HIV replication

Targeting Virus-host Interactions of HIV Replication

Validation and structural characterization of the LEDGF/p75-MLL interface as a new target for the treatment of MLL-dependent leukemia

Transient and Stable Knockdown of the Integrase Cofactor LEDGF/p75 Reveals Its Role in the Replication Cycle of Human Immunodeficiency Virus

Overexpression of the Lens Epithelium-Derived Growth Factor/p75 Integrase Binding Domain Inhibits Human Immunodeficiency Virus Replication

Y-box-binding protein 1 supports the early and late steps of HIV replication

Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif

Retroviral integration: Site matters

HRP-2 determines HIV-1 integration site selection in LEDGF/p75 depleted cells

Toward the Discovery of Novel Anti-HIV Drugs. Second-Generation Inhibitors of the Cellular ATPase DDX3 with Improved Anti-HIV Activity: Synthesis, Structure-Activity Relationship Analysis, Cytotoxicity Studies, and Target Validation

Correction to: HIV-1 IN/Pol recruits LEDGF/p75 into viral particles

Lens Epithelium-derived Growth Factor/p75 Interacts with the Transposase-derived DDE Domain of PogZ

BET-Independent Murine Leukemia Virus Integration Is Retargeted In Vivo and Selects Distinct Genomic Elements for Lymphomagenesis

Correction to: LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions

BET-independent MLV-based Vectors Target Away From Promoters and Regulatory Elements

Impact of the Central Polypurine Tract on the Kinetics of Human Immunodeficiency Virus Type 1 Vector Transduction

Engineering Next-Generation BET-Independent MLV Vectors for Safer Gene Therapy

Unlike Its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival

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