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Pharmacological chaperones improve intra-domain stability and inter-domain assembly via distinct binding sites to rescue misfolded CFTR

Cellular and molecular life sciences : CMLS, 2021-12, Vol.78 (23), p.7813-7829

2021

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Bacterial lipid membranes as promising targets to fight antimicrobial resistance, molecular foundations and illustration through the renewal of aminoglycoside antibiotics and emergence of amphiphilic aminoglycosides

MedChemComm, 2016-04, Vol.7 (4), p.586-611

2016

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New 7‑Methylguanine Derivatives Targeting the Influenza Polymerase PB2 Cap-Binding Domain

Journal of medicinal chemistry, 2013-11, Vol.56 (21), p.8915-8930

2013

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Amphiphilic Aminoglycosides as Medicinal Agents

International journal of molecular sciences, 2020-10, Vol.21 (19), p.7411

2020

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A One-Pot Synthesis of Highly Functionalized Purines

Organic letters, 2017-12, Vol.19 (23), p.6360-6363

2017

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Combining theoretical and experimental data to decipher CFTR 3D structures and functions

Cellular and molecular life sciences : CMLS, 2018-10, Vol.75 (20), p.3829-3855

2018

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New Broad-Spectrum Antibacterial Amphiphilic Aminoglycosides Active against Resistant Bacteria: From Neamine Derivatives to Smaller Neosamine Analogues

Journal of medicinal chemistry, 2016-10, Vol.59 (20), p.9350-9369

2016

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Targeting Bacterial Cardiolipin Enriched Microdomains: An Antimicrobial Strategy Used by Amphiphilic Aminoglycoside Antibiotics

Scientific reports, 2017-09, Vol.7 (1), p.10697-12, Article 10697

2017

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Effect of cardiolipin on the antimicrobial activity of a new amphiphilic aminoglycoside derivative on Pseudomonas aeruginosa

PloS one, 2018-08, Vol.13 (8), p.e0201752-e0201752

2018

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Broad-spectrum antibacterial amphiphilic aminoglycosides: A new focus on the structure of the lipophilic groups extends the series of active dialkyl neamines

European journal of medicinal chemistry, 2018-09, Vol.157, p.1512-1525

2018

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Antimicrobial activity of amphiphilic neamine derivatives: Understanding the mechanism of action on Gram-positive bacteria

Biochimica et biophysica acta. Biomembranes, 2019-10, Vol.1861 (10), p.182998-182998, Article 182998

2019

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Negatively Charged Lipids as a Potential Target for New Amphiphilic Aminoglycoside Antibiotics: A BIOPHYSICAL STUDY

The Journal of biological chemistry, 2016-06, Vol.291 (26), p.13864-13874

2016

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Tuning the Antibacterial Activity of Amphiphilic Neamine Derivatives and Comparison to Paromamine Homologues

Journal of medicinal chemistry, 2013-10, Vol.56 (19), p.7691-7705

2013

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Interest of Homodialkyl Neamine Derivatives against Resistant P. aeruginosa, E. coli, and β-Lactamases-Producing Bacteria—Effect of Alkyl Chain Length on the Interaction with LPS

International journal of molecular sciences, 2021-08, Vol.22 (16), p.8707

2021

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A Peptide Nucleic Acid–Aminosugar Conjugate Targeting Transactivation Response Element of HIV-1 RNA Genome Shows a High Bioavailability in Human Cells and Strongly Inhibits Tat-Mediated Transactivation of HIV-1 Transcription

Journal of medicinal chemistry, 2012-07, Vol.55 (13), p.6021-6032

2012

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Synthesis and Antimicrobial Evaluation of Amphiphilic Neamine Derivatives

Journal of medicinal chemistry, 2010-01, Vol.53 (1), p.119-127

2010

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New Amphiphilic Neamine Derivatives Active against Resistant Pseudomonas aeruginosa and Their Interactions with Lipopolysaccharides

Antimicrobial agents and chemotherapy, 2014-08, Vol.58 (8), p.4420-4430

2014

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6‐Chloropurine Ribonucleosides from Chloropyrimidines: One‐Pot Synthesis

Current Protocols in Nucleic Acid Chemistry, 2018-09, Vol.74 (1), p.e57-n/a

2018

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Antibiotic Drugs Aminoglycosides Cleave DNA at Abasic Sites: Shedding New Light on Their Toxicity?

Chemical research in toxicology, 2013-11, Vol.26 (11), p.1710-1719

2013

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Corrigendum: Synthesis and Evaluation of 2‐Aminothiophene Derivatives as Staphylococcus aureus Efflux Pump Inhibitors

ChemMedChem, 2021-05, Vol.16 (10), p.1680-1680

2021

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Synthesis and Transfection Properties of a Series of Lipidic Neamine Derivatives

Bioconjugate chemistry, 2009-11, Vol.20 (11), p.2032-2046

2009

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Aptamer-Based Enantioselective Competitive Binding Assay for the Trace Enantiomer Detection

Analytical chemistry (Washington), 2007-06, Vol.79 (12), p.4716-4719

2007

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Covalently bonded DNA aptamer chiral stationary phase for the chromatographic resolution of adenosine

Analytical and bioanalytical chemistry, 2008-02, Vol.390 (4), p.1051-1057

2008

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A new 9-alkyladenine-cyclic methylglyoxal diadduct activates wt- and F508del-cystic fibrosis transmembrane conductance regulator (CFTR) in vitro and in vivo

European journal of medicinal chemistry, 2014-08, Vol.83, p.455-465

2014

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An evolutionary conserved detoxification system for membrane lipid-derived peroxyl radicals in Gram-negative bacteria

PLoS biology, 2022-05, Vol.20 (5), p.e3001610-e3001610

2022

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Pharmacological chaperones improve intra-domain stability and inter-domain assembly via distinct binding sites to rescue misfolded CFTR

Bacterial lipid membranes as promising targets to fight antimicrobial resistance, molecular foundations and illustration through the renewal of aminoglycoside antibiotics and emergence of amphiphilic aminoglycosides

New 7‑Methylguanine Derivatives Targeting the Influenza Polymerase PB2 Cap-Binding Domain

Amphiphilic Aminoglycosides as Medicinal Agents

A One-Pot Synthesis of Highly Functionalized Purines

Combining theoretical and experimental data to decipher CFTR 3D structures and functions

New Broad-Spectrum Antibacterial Amphiphilic Aminoglycosides Active against Resistant Bacteria: From Neamine Derivatives to Smaller Neosamine Analogues

Targeting Bacterial Cardiolipin Enriched Microdomains: An Antimicrobial Strategy Used by Amphiphilic Aminoglycoside Antibiotics

Effect of cardiolipin on the antimicrobial activity of a new amphiphilic aminoglycoside derivative on Pseudomonas aeruginosa

Broad-spectrum antibacterial amphiphilic aminoglycosides: A new focus on the structure of the lipophilic groups extends the series of active dialkyl neamines

Antimicrobial activity of amphiphilic neamine derivatives: Understanding the mechanism of action on Gram-positive bacteria

Negatively Charged Lipids as a Potential Target for New Amphiphilic Aminoglycoside Antibiotics: A BIOPHYSICAL STUDY

Tuning the Antibacterial Activity of Amphiphilic Neamine Derivatives and Comparison to Paromamine Homologues

Interest of Homodialkyl Neamine Derivatives against Resistant P. aeruginosa, E. coli, and β-Lactamases-Producing Bacteria—Effect of Alkyl Chain Length on the Interaction with LPS

A Peptide Nucleic Acid–Aminosugar Conjugate Targeting Transactivation Response Element of HIV-1 RNA Genome Shows a High Bioavailability in Human Cells and Strongly Inhibits Tat-Mediated Transactivation of HIV-1 Transcription

Synthesis and Antimicrobial Evaluation of Amphiphilic Neamine Derivatives

New Amphiphilic Neamine Derivatives Active against Resistant Pseudomonas aeruginosa and Their Interactions with Lipopolysaccharides

6‐Chloropurine Ribonucleosides from Chloropyrimidines: One‐Pot Synthesis

Antibiotic Drugs Aminoglycosides Cleave DNA at Abasic Sites: Shedding New Light on Their Toxicity?

Corrigendum: Synthesis and Evaluation of 2‐Aminothiophene Derivatives as Staphylococcus aureus Efflux Pump Inhibitors

Synthesis and Transfection Properties of a Series of Lipidic Neamine Derivatives

Aptamer-Based Enantioselective Competitive Binding Assay for the Trace Enantiomer Detection

Covalently bonded DNA aptamer chiral stationary phase for the chromatographic resolution of adenosine

A new 9-alkyladenine-cyclic methylglyoxal diadduct activates wt- and F508del-cystic fibrosis transmembrane conductance regulator (CFTR) in vitro and in vivo

An evolutionary conserved detoxification system for membrane lipid-derived peroxyl radicals in Gram-negative bacteria

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