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Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses

eLife, 2023-09, Vol.12

2023

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RADAR: differential analysis of MeRIP-seq data with a random effect model

Genome Biology, 2019-12, Vol.20 (1), p.294-294, Article 294

2019

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SerpinB1 Promotes Pancreatic β Cell Proliferation

Cell metabolism, 2016-01, Vol.23 (1), p.194-205

2016

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Luseogliflozin increases beta cell proliferation through humoral factors that activate an insulin receptor- and IGF-1 receptor-independent pathway

Diabetologia, 2020-03, Vol.63 (3), p.577-587

2020

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SUCNR1 regulates insulin secretion and glucose elevates the succinate response in people with prediabetes

The Journal of clinical investigation, 2024-06, Vol.134 (12)

2024

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Secreted EMC10 is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity in mice

Nature communications, 2022-11, Vol.13 (1), p.7323-17, Article 7323

2022

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E2F1 transcription factor mediates a link between fat and islets to promote β cell proliferation in response to acute insulin resistance

Cell reports (Cambridge), 2022-10, Vol.41 (1), p.111436-111436, Article 111436

2022

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“Omics” and “epi-omics” underlying the β-cell adaptation to insulin resistance

Molecular metabolism (Germany), 2019-09, Vol.27 (Suppl), p.S42-S48

2019

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Excessive Cellular Proliferation Negatively Impacts Reprogramming Efficiency of Human Fibroblasts

Stem cells translational medicine, 2015-10, Vol.4 (10), p.1101-1108

2015

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Insulin receptor-mediated signaling regulates pluripotency markers and lineage differentiation

Molecular metabolism (Germany), 2018-12, Vol.18, p.153-163

2018

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NREP contributes to development of NAFLD by regulating one-carbon metabolism in primary human hepatocytes

Cell chemical biology, 2023-09, Vol.30 (9), p.1144-1155.e4

2023

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Parental metabolic syndrome epigenetically reprograms offspring hepatic lipid metabolism in mice

The Journal of clinical investigation, 2020-05, Vol.130 (5), p.2391-2407

2020

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Epigenetic modifiers of islet function and mass

Trends in endocrinology and metabolism, 2014-12, Vol.25 (12), p.628-636

2014

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m6A mRNA methylation in brown fat regulates systemic insulin sensitivity via an inter-organ prostaglandin signaling axis independent of UCP1

Cell metabolism, 2024-10, Vol.36 (10), p.2207-2227.e9

2024

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Maternal insulin resistance and transient hyperglycemia impact the metabolic and endocrine phenotypes of offspring

American journal of physiology: endocrinology and metabolism, 2014-11, Vol.307 (10), p.E906-E918

2014

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Deficiency of the metabolic enzyme SCHAD in pancreatic β-cells promotes amino acid–sensitive hypoglycemia

The Journal of biological chemistry, 2023-08, Vol.299 (8), p.104986, Article 104986

2023

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Redox regulation of m6A methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes

Nature cell biology, 2024-03, Vol.26 (3), p.421-437

2024

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Hepatic IRF3 fuels dysglycemia in obesity through direct regulation of Ppp2r1b

Science translational medicine, 2022-03, Vol.14 (637), p.eabh3831

2022

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Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways

Cell metabolism, 2023-07, Vol.35 (7), p.1242-1260.e9

2023

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Loss-of-Function Mutation in Thiamine Transporter 1 in a Family With Autosomal Dominant Diabetes

Diabetes (New York, N.Y.), 2019-05, Vol.68 (5), p.1084-1093

2019

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Soluble factors secreted by T cells promote β-cell proliferation

Diabetes (New York, N.Y.), 2014-01, Vol.63 (1), p.188-202

2014

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Human duct cells contribute to β cell compensation in insulin resistance

JCI insight, 2019-04, Vol.4 (8)

2019

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198-OR: Pancreatic Elastase Regulates Human Beta-Cell Viability by Impairing the PAR2 Pathway

Diabetes (New York, N.Y.), 2023-06, Vol.72 (Supplement_1), p.1

2023

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More is better: combinatorial therapy to restore β-cell function in diabetes

Nature metabolism, 2020-02, Vol.2 (2), p.130-131

2020

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Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses

RADAR: differential analysis of MeRIP-seq data with a random effect model

SerpinB1 Promotes Pancreatic β Cell Proliferation

Luseogliflozin increases beta cell proliferation through humoral factors that activate an insulin receptor- and IGF-1 receptor-independent pathway

SUCNR1 regulates insulin secretion and glucose elevates the succinate response in people with prediabetes

Secreted EMC10 is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity in mice

E2F1 transcription factor mediates a link between fat and islets to promote β cell proliferation in response to acute insulin resistance

“Omics” and “epi-omics” underlying the β-cell adaptation to insulin resistance

Excessive Cellular Proliferation Negatively Impacts Reprogramming Efficiency of Human Fibroblasts

Insulin receptor-mediated signaling regulates pluripotency markers and lineage differentiation

NREP contributes to development of NAFLD by regulating one-carbon metabolism in primary human hepatocytes

Parental metabolic syndrome epigenetically reprograms offspring hepatic lipid metabolism in mice

Epigenetic modifiers of islet function and mass

m6A mRNA methylation in brown fat regulates systemic insulin sensitivity via an inter-organ prostaglandin signaling axis independent of UCP1

Maternal insulin resistance and transient hyperglycemia impact the metabolic and endocrine phenotypes of offspring

Deficiency of the metabolic enzyme SCHAD in pancreatic β-cells promotes amino acid–sensitive hypoglycemia

Redox regulation of m6A methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes

Hepatic IRF3 fuels dysglycemia in obesity through direct regulation of Ppp2r1b

A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism

Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways

Loss-of-Function Mutation in Thiamine Transporter 1 in a Family With Autosomal Dominant Diabetes

Soluble factors secreted by T cells promote β-cell proliferation

Human duct cells contribute to β cell compensation in insulin resistance

198-OR: Pancreatic Elastase Regulates Human Beta-Cell Viability by Impairing the PAR2 Pathway

More is better: combinatorial therapy to restore β-cell function in diabetes

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