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More expansive gene transfer to the rat CNS: AAV PHP.EB vector dose-response and comparison to AAV PHP.B

Gene therapy, 2018-08, Vol.25 (5), p.392-400

2018

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TDP43 nuclear export and neurodegeneration in models of amyotrophic lateral sclerosis and frontotemporal dementia

Scientific reports, 2018-03, Vol.8 (1), p.4606-18, Article 4606

2018

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The advent of AAV9 expands applications for brain and spinal cord gene delivery

Expert opinion on biological therapy, 2012-06, Vol.12 (6), p.757-766

2012

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Better Targeting, Better Efficiency for Wide-Scale Neuronal Transduction with the Synapsin Promoter and AAV-PHP.B

Frontiers in molecular neuroscience, 2016-11, Vol.9, p.116-116

2016

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AAV8, 9, Rh10, Rh43 Vector Gene Transfer in the Rat Brain: Effects of Serotype, Promoter and Purification Method

Molecular therapy, 2008-01, Vol.16 (1), p.89-96

2008

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Histopathological evidence that diethylene glycol produces kidney and nervous system damage in rats

Neurotoxicology (Park Forest South), 2022-07, Vol.91, p.200-210

2022

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p62 Pathology Model in the Rat Substantia Nigra with Filamentous Inclusions and Progressive Neurodegeneration

PloS one, 2017-01, Vol.12 (1), p.e0169291

2017

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Selective Forelimb Impairment in Rats Expressing a Pathological TDP-43 25 kDa C-terminal Fragment to Mimic Amyotrophic Lateral Sclerosis

Molecular therapy, 2013-07, Vol.21 (7), p.1324-1334

2013

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Mimicking Aspects of Frontotemporal Lobar Degeneration and Lou Gehrig's Disease in Rats via TDP-43 Overexpression

Molecular therapy, 2009-04, Vol.17 (4), p.607-613

2009

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Expansive Gene Transfer in the Rat CNS Rapidly Produces Amyotrophic Lateral Sclerosis Relevant Sequelae When TDP-43 is Overexpressed

Molecular therapy, 2010-12, Vol.18 (12), p.2064-2074

2010

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AAV9 supports wide-scale transduction of the CNS and TDP-43 disease modeling in adult rats

Molecular therapy. Methods & clinical development, 2015-01, Vol.2, p.15036-15036, Article 15036

2015

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Entorhinal tau pathology disrupts hippocampal-prefrontal oscillatory coupling during associative learning

Neurobiology of aging, 2017-10, Vol.58, p.151-162

2017

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Parkin is protective for substantia nigra dopamine neurons in a tau gene transfer neurodegeneration model

Neuroscience letters, 2006-06, Vol.401 (1), p.130-135

2006

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Diethylene glycol produces nephrotoxic and neurotoxic effects in female rats

Clinical toxicology (Philadelphia, Pa.), 2022-03, Vol.60 (3), p.324-331

2022

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Neurotoxic effects of nephrotoxic compound diethylene glycol

Clinical toxicology (Philadelphia, Pa.), 2021-09, Vol.59 (9), p.810-821

2021

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Cre‐dependent AAV vectors for highly targeted expression of disease‐related proteins and neurodegeneration in the substantia nigra

The FASEB journal, 2018-08, Vol.32 (8), p.4420-4427

2018

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Highly socially vulnerable communities exhibit disproportionately increased viral loads as measured in community wastewater

Environmental research, 2023-04, Vol.222, p.115351, Article 115351

2023

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Tau gene transfer, but not alpha-synuclein, induces both progressive dopamine neuron degeneration and rotational behavior in the rat

Neurobiology of disease, 2005-10, Vol.20 (1), p.64-73

2005

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PET imaging in rats to discern temporal onset differences between 6-hydroxydopamine and tau gene vector neurodegeneration models

Brain research, 2009-03, Vol.1259, p.113-122

2009

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Efficient Neuronal Gene Transfer with AAV8 Leads to Neurotoxic Levels of Tau or Green Fluorescent Proteins

Molecular therapy, 2006-03, Vol.13 (3), p.517-527

2006

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Gene vector 'magic bullet': targeted expression in the central nervous system after peripheral delivery using the synapsin promoter

Expert opinion on therapeutic targets, 2016-10, Vol.20 (10), p.1153-1154

2016

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Recombinant AAV9-TLK1B administration ameliorates fractionated radiation-induced xerostomia

Human gene therapy, 2013-06, Vol.24 (6), p.604

2013

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Gene Transfer Induced Hypercholesterolemia in Amyloid Mice

Journal of Alzheimer's disease, 2018-01, Vol.65 (4), p.1079

2018

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Severe respiratory changes at end stage in a FUS-induced disease state in adult rats

BMC neuroscience, 2016-10, Vol.17 (1), p.69, Article 69

2016

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Pronounced microgliosis and neurodegeneration in aged rats after tau gene transfer

Neurobiology of aging, 2010-12, Vol.31 (12), p.2091-2102

2010

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More expansive gene transfer to the rat CNS: AAV PHP.EB vector dose-response and comparison to AAV PHP.B

TDP43 nuclear export and neurodegeneration in models of amyotrophic lateral sclerosis and frontotemporal dementia

The advent of AAV9 expands applications for brain and spinal cord gene delivery

Better Targeting, Better Efficiency for Wide-Scale Neuronal Transduction with the Synapsin Promoter and AAV-PHP.B

AAV8, 9, Rh10, Rh43 Vector Gene Transfer in the Rat Brain: Effects of Serotype, Promoter and Purification Method

Histopathological evidence that diethylene glycol produces kidney and nervous system damage in rats

p62 Pathology Model in the Rat Substantia Nigra with Filamentous Inclusions and Progressive Neurodegeneration

Selective Forelimb Impairment in Rats Expressing a Pathological TDP-43 25 kDa C-terminal Fragment to Mimic Amyotrophic Lateral Sclerosis

Mimicking Aspects of Frontotemporal Lobar Degeneration and Lou Gehrig's Disease in Rats via TDP-43 Overexpression

Expansive Gene Transfer in the Rat CNS Rapidly Produces Amyotrophic Lateral Sclerosis Relevant Sequelae When TDP-43 is Overexpressed

AAV9 supports wide-scale transduction of the CNS and TDP-43 disease modeling in adult rats

Entorhinal tau pathology disrupts hippocampal-prefrontal oscillatory coupling during associative learning

Parkin is protective for substantia nigra dopamine neurons in a tau gene transfer neurodegeneration model

Diethylene glycol produces nephrotoxic and neurotoxic effects in female rats

Neurotoxic effects of nephrotoxic compound diethylene glycol

Cre‐dependent AAV vectors for highly targeted expression of disease‐related proteins and neurodegeneration in the substantia nigra

Highly socially vulnerable communities exhibit disproportionately increased viral loads as measured in community wastewater

Tau gene transfer, but not alpha-synuclein, induces both progressive dopamine neuron degeneration and rotational behavior in the rat

PET imaging in rats to discern temporal onset differences between 6-hydroxydopamine and tau gene vector neurodegeneration models

Efficient Neuronal Gene Transfer with AAV8 Leads to Neurotoxic Levels of Tau or Green Fluorescent Proteins

Gene vector 'magic bullet': targeted expression in the central nervous system after peripheral delivery using the synapsin promoter

Recombinant AAV9-TLK1B administration ameliorates fractionated radiation-induced xerostomia

Gene Transfer Induced Hypercholesterolemia in Amyloid Mice

Severe respiratory changes at end stage in a FUS-induced disease state in adult rats

Pronounced microgliosis and neurodegeneration in aged rats after tau gene transfer

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