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Glycointeractions in bacterial pathogenesis

Nature reviews. Microbiology, 2018-07, Vol.16 (7), p.440-452

2018

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MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition

Nature chemical biology, 2019-06, Vol.15 (6), p.556

2019

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Staphylococcus aureus LukAB cytotoxin kills human neutrophils by targeting the CD11b subunit of the integrin Mac-1

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (26), p.10794-10799

2013

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Safety, Tolerability, and Population Pharmacokinetics of Intravenous and Oral Isavuconazonium Sulfate in Pediatric Patients

Antimicrobial agents and chemotherapy, 2021-07, Vol.65 (8), p.e0029021

2021

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Multidisciplinary Approaches Identify Compounds that Bind to Human ACE2 or SARS-CoV-2 Spike Protein as Candidates to Block SARS-CoV-2-ACE2 Receptor Interactions

mBio, 2021-03, Vol.12 (2)

2021

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Glycan: glycan interactions: High affinity biomolecular interactions that can mediate binding of pathogenic bacteria to host cells

Proceedings of the National Academy of Sciences - PNAS, 2015-12, Vol.112 (52), p.E7266-E7275

2015

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cholesterol-dependent cytolysins pneumolysin and streptolysin O require binding to red blood cell glycans for hemolytic activity

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (49), p.E5312-E5320

2014

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Staphylococcus aureus Targets the Duffy Antigen Receptor for Chemokines (DARC) to Lyse Erythrocytes

Cell host & microbe, 2015-09, Vol.18 (3), p.363-370

2015

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Characterisation of a multi-ligand binding chemoreceptor CcmL (Tlp3) of Campylobacter jejuni

PLoS pathogens, 2014-01, Vol.10 (1), p.e1003822-e1003822

2014

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The cell surface protein MUL_3720 confers binding of the skin pathogen Mycobacterium ulcerans to sulfated glycans and keratin

PLoS neglected tropical diseases, 2021-02, Vol.15 (2), p.e0009136-e0009136

2021

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A direct-sensing galactose chemoreceptor recently evolved in invasive strains of Campylobacter jejuni

Nature communications, 2016-10, Vol.7 (1), p.13206-13206, Article 13206

2016

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N-glycolylneuraminic acid as a carbohydrate cancer biomarker

Translational oncology, 2023-05, Vol.31, p.101643-101643, Article 101643

2023

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The Three-dimensional Structure of the Extracellular Adhesion Domain of the Sialic Acid-binding Adhesin SabA from Helicobacter pylori

The Journal of biological chemistry, 2014-03, Vol.289 (10), p.6332-6340

2014

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Repurposed Drugs That Block the Gonococcus-Complement Receptor 3 Interaction Can Prevent and Cure Gonococcal Infection of Primary Human Cervical Epithelial Cells

mBio, 2020-03, Vol.11 (2)

2020

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The dCache Chemoreceptor TlpA of Helicobacter pylori Binds Multiple Attractant and Antagonistic Ligands via Distinct Sites

mBio, 2021-08, Vol.12 (4), p.e0181921

2021

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N-glycolylneuraminic acid serum biomarker levels are elevated in breast cancer patients at all stages of disease

BMC cancer, 2022-03, Vol.22 (1), p.334-334, Article 334

2022

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The mechanics of myeloid cells

Biology of the cell, 2020-04, Vol.112 (4), p.103-112

2020

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Identification of a Crucial Residue Required for Staphylococcus aureus LukAB Cytotoxicity and Receptor Recognition

Infection and Immunity, 2014-03, Vol.82 (3), p.1268-1276

2014

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Complement Receptor 3 Mediates HIV-1 Transcytosis across an Intact Cervical Epithelial Cell Barrier: New Insight into HIV Transmission in Women

mBio, 2022-02, Vol.13 (1), p.e0217721-e0217721

2022

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The essential malaria protein PfCyRPA targets glycans to invade erythrocytes

Cell reports (Cambridge), 2024-04, Vol.43 (4), p.114012-114012, Article 114012

2024

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The Neisseria gonorrhoeae Vaccine Candidate NHBA Elicits Antibodies That Are Bactericidal, Opsonophagocytic and That Reduce Gonococcal Adherence to Epithelial Cells

Vaccines (Basel), 2020-05, Vol.8 (2), p.219

2020

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Structure and function of nucleotide sugar transporters: Current progress

Computational and structural biotechnology journal, 2014-06, Vol.10 (16), p.23-32

2014

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Glycointeractome of Neisseria gonorrhoeae: Identification of Host Glycans Targeted by the Gonococcus To Facilitate Adherence to Cervical and Urethral Epithelial Cells

mBio, 2019-07, Vol.10 (4)

2019

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Discovery of Bacterial Fimbria-Glycan Interactions Using Whole-Cell Recombinant Escherichia coli Expression

mBio, 2021-02, Vol.12 (1)

2021

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Carbohydrate Recognition Specificity of Trans-sialidase Lectin Domain from Trypanosoma congolense

PLoS neglected tropical diseases, 2015-10, Vol.9 (10), p.e0004120-e0004120

2015

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Glycointeractions in bacterial pathogenesis

MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition

Staphylococcus aureus LukAB cytotoxin kills human neutrophils by targeting the CD11b subunit of the integrin Mac-1

Safety, Tolerability, and Population Pharmacokinetics of Intravenous and Oral Isavuconazonium Sulfate in Pediatric Patients

Multidisciplinary Approaches Identify Compounds that Bind to Human ACE2 or SARS-CoV-2 Spike Protein as Candidates to Block SARS-CoV-2-ACE2 Receptor Interactions

Glycan: glycan interactions: High affinity biomolecular interactions that can mediate binding of pathogenic bacteria to host cells

cholesterol-dependent cytolysins pneumolysin and streptolysin O require binding to red blood cell glycans for hemolytic activity

Staphylococcus aureus Targets the Duffy Antigen Receptor for Chemokines (DARC) to Lyse Erythrocytes

Characterisation of a multi-ligand binding chemoreceptor CcmL (Tlp3) of Campylobacter jejuni

The cell surface protein MUL_3720 confers binding of the skin pathogen Mycobacterium ulcerans to sulfated glycans and keratin

A direct-sensing galactose chemoreceptor recently evolved in invasive strains of Campylobacter jejuni

N-glycolylneuraminic acid as a carbohydrate cancer biomarker

The Three-dimensional Structure of the Extracellular Adhesion Domain of the Sialic Acid-binding Adhesin SabA from Helicobacter pylori

Repurposed Drugs That Block the Gonococcus-Complement Receptor 3 Interaction Can Prevent and Cure Gonococcal Infection of Primary Human Cervical Epithelial Cells

The dCache Chemoreceptor TlpA of Helicobacter pylori Binds Multiple Attractant and Antagonistic Ligands via Distinct Sites

N-glycolylneuraminic acid serum biomarker levels are elevated in breast cancer patients at all stages of disease

The mechanics of myeloid cells

Identification of a Crucial Residue Required for Staphylococcus aureus LukAB Cytotoxicity and Receptor Recognition

Complement Receptor 3 Mediates HIV-1 Transcytosis across an Intact Cervical Epithelial Cell Barrier: New Insight into HIV Transmission in Women

The essential malaria protein PfCyRPA targets glycans to invade erythrocytes

The Neisseria gonorrhoeae Vaccine Candidate NHBA Elicits Antibodies That Are Bactericidal, Opsonophagocytic and That Reduce Gonococcal Adherence to Epithelial Cells

Structure and function of nucleotide sugar transporters: Current progress

Glycointeractome of Neisseria gonorrhoeae: Identification of Host Glycans Targeted by the Gonococcus To Facilitate Adherence to Cervical and Urethral Epithelial Cells

Discovery of Bacterial Fimbria-Glycan Interactions Using Whole-Cell Recombinant Escherichia coli Expression

Carbohydrate Recognition Specificity of Trans-sialidase Lectin Domain from Trypanosoma congolense

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