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Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics

Cancer research (Chicago, Ill.), 2007-10, Vol.67 (19), p.9472-9481

2007

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A Family of Mammalian E3 Ubiquitin Ligases That Contain the UBR Box Motif and Recognize N-Degrons

Molecular and Cellular Biology, 2005-08, Vol.25 (16), p.7120-7136

2005

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RGS4 and RGS5 Are in vivo Substrates of the N-End Rule Pathway

Proceedings of the National Academy of Sciences - PNAS, 2005-10, Vol.102 (42), p.15030-15035

2005

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Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cells

Cancer cell, 2005-06, Vol.7 (6), p.547-559

2005

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An Essential Role of N-Terminal Arginylation in Cardiovascular Development

Science (American Association for the Advancement of Science), 2002-07, Vol.297 (5578), p.96-99

2002

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Female Lethality and Apoptosis of Spermatocytes in Mice Lacking the UBR2 Ubiquitin Ligase of the N-End Rule Pathway

Molecular and Cellular Biology, 2003-11, Vol.23 (22), p.8255-8271

2003

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Arginyltransferase, Its Specificity, Putative Substrates, Bidirectional Promoter, and Splicing-derived Isoforms

The Journal of biological chemistry, 2006-10, Vol.281 (43), p.32559-32573

2006

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Identification of Inhibitors for MDM2 Ubiquitin Ligase Activity from Natural Product Extracts by a Novel High-Throughput Electrochemiluminescent Screen

Journal of biomolecular screening, 2008-03, Vol.13 (3), p.229-237

2008

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RGS4 Is Arginylated and Degraded by the N-end Rule Pathway in Vitro

The Journal of biological chemistry, 2000-07, Vol.275 (30), p.22931-22941

2000

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Detection of fg/mL Levels of IL-2, IL-4, IL-6, IL-10, and IL-17A in Serum, Plasma, and Supernatant of Established Cell Models

The Journal of immunology (1950), 2017-05, Vol.198 (1_Supplement), p.61-61.6

2017

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Th2-Specific Protein/DNA Interactions at the Proximal Nuclear Factor-AT Site Contribute to the Functional Activity of the Human IL-4 Promoter

The Journal of immunology (1950), 1998-08, Vol.161 (3), p.1380-1389

1998

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Assays for High‐Throughput Screening of E2 and E3 Ubiquitin Ligases

Methods in Enzymology, 2005, Vol.399, p.682-701

2005

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Construction and Analysis of Mouse Strains Lacking the Ubiquitin Ligase UBR1 (E3α) of the N-End Rule Pathway

Molecular and Cellular Biology, 2001-12, Vol.21 (23), p.8007-8021

2001

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Altered Activity, Social Behavior, and Spatial Memory in Mice Lacking the NTAN1p Amidase and the Asparagine Branch of the N-End Rule Pathway

Molecular and Cellular Biology, 2000-06, Vol.20 (11), p.4135-4148

2000

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In Vitro Screening for Substrates of the N‐End Rule–Dependent Ubiquitylation

Methods in Enzymology, 2005, Vol.399, p.415-432

2005

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Rapid Immunoassay Development using the U-PLEX® Assay Platform

The Journal of immunology (1950), 2017-05, Vol.198 (1_Supplement), p.81-81.18

2017

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Differential interaction of nuclear factors with the PRE-I enhancer element of the human IL-4 promoter in different T cell subsets

The Journal of immunology (1950), 1997-02, Vol.158 (3), p.1194-1200

1997

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The role of NF-Y and IRF-2 in the regulation of human IL-4 gene expression

The Journal of immunology (1950), 1994-11, Vol.153 (9), p.4122-4133

1994

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The N-End Rule Pathway inXenopusEgg Extracts

Archives of biochemistry and biophysics, 1998-09, Vol.357 (2), p.317-325

1998

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The N-end rule pathway in Xenopus egg extracts

Archives of biochemistry and biophysics, 1998-09, Vol.357 (2), p.317-325

1998

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Cloning of the cDNA encoding human C/EBPγ, a protein binding to the PRE-I enhancer element of the human interleukin-4 promoter

Gene, 1995-08, Vol.161 (2), p.271-275

1995

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What Controls Tissue-specific Expression of the IL-4 Gene?

Immunobiology (1979), 1997-12, Vol.198 (1), p.170-178

1997

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NF-Y, IRF-2, and C/EBP Proteins are Involved in Regulation of Human IL-4 Gene Expression

Immunobiology (1979), 1995-07, Vol.193 (2), p.263-267

1995

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Molecular Sequence Data
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Interleukin-4 - Genetics
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Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics

A Family of Mammalian E3 Ubiquitin Ligases That Contain the UBR Box Motif and Recognize N-Degrons

RGS4 and RGS5 Are in vivo Substrates of the N-End Rule Pathway

Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cells

An Essential Role of N-Terminal Arginylation in Cardiovascular Development

Female Lethality and Apoptosis of Spermatocytes in Mice Lacking the UBR2 Ubiquitin Ligase of the N-End Rule Pathway

Arginyltransferase, Its Specificity, Putative Substrates, Bidirectional Promoter, and Splicing-derived Isoforms

Identification of Inhibitors for MDM2 Ubiquitin Ligase Activity from Natural Product Extracts by a Novel High-Throughput Electrochemiluminescent Screen

RGS4 Is Arginylated and Degraded by the N-end Rule Pathway in Vitro

Detection of fg/mL Levels of IL-2, IL-4, IL-6, IL-10, and IL-17A in Serum, Plasma, and Supernatant of Established Cell Models

Th2-Specific Protein/DNA Interactions at the Proximal Nuclear Factor-AT Site Contribute to the Functional Activity of the Human IL-4 Promoter

Assays for High‐Throughput Screening of E2 and E3 Ubiquitin Ligases

Construction and Analysis of Mouse Strains Lacking the Ubiquitin Ligase UBR1 (E3α) of the N-End Rule Pathway

Altered Activity, Social Behavior, and Spatial Memory in Mice Lacking the NTAN1p Amidase and the Asparagine Branch of the N-End Rule Pathway

In Vitro Screening for Substrates of the N‐End Rule–Dependent Ubiquitylation

Rapid Immunoassay Development using the U-PLEX® Assay Platform

Differential interaction of nuclear factors with the PRE-I enhancer element of the human IL-4 promoter in different T cell subsets

The role of NF-Y and IRF-2 in the regulation of human IL-4 gene expression

The N-End Rule Pathway inXenopusEgg Extracts

The N-end rule pathway in Xenopus egg extracts

Cloning of the cDNA encoding human C/EBPγ, a protein binding to the PRE-I enhancer element of the human interleukin-4 promoter

What Controls Tissue-specific Expression of the IL-4 Gene?

NF-Y, IRF-2, and C/EBP Proteins are Involved in Regulation of Human IL-4 Gene Expression

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