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Pica in Rats as a Preclinical Model of Emesis

Current Protocols in Neuroscience, 2016-10, Vol.77 (1), p.9.53.1

Davis, T Gregg

2016

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The identification of a novel phosphodiesterase 4 inhibitor, 1-ethyl-5-{5-[(4-methyl-1-piperazinyl)methyl]-1,3,4-oxadiazol-2-yl}-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-b]pyridin-4-amine (EPPA-1), with improved therapeutic index using pica feeding in rats as a measure of emetogenicity

The Journal of pharmacology and experimental therapeutics, 2009-09, Vol.330 (3), p.922

2009

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Rapid Lipid Mediator Profiling by Convergence Chromatography-MS/MS

Methods in molecular biology (Clifton, N.J.), 2025, Vol.2855, p.341

2025

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GSK356278, a potent, selective, brain-penetrant phosphodiesterase 4 inhibitor that demonstrates anxiolytic and cognition-enhancing effects without inducing side effects in preclinical species

The Journal of pharmacology and experimental therapeutics, 2014-07, Vol.350 (1), p.153-163

2014

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Prostaglandin Metabolites Analysis in Urine by LC-MS/MS

Methods in molecular biology (Clifton, N.J.), 2025, Vol.2855, p.147

2025

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Inhibition of Invariant Chain Processing, Antigen-Induced Proliferative Responses, and the Development of Collagen-Induced Arthritis and Experimental Autoimmune Encephalomyelitis by a Small Molecule Cysteine Protease Inhibitor

The Journal of immunology (1950), 2008-06, Vol.180 (12), p.7989-8003

2008

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Endothelin B Receptor Modulates Inflammatory Pain and Cutaneous Inflammation

Molecular pharmacology, 1999-10, Vol.56 (4), p.807

1999

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Attenuation of Murine Collagen-Induced Arthritis by a Novel, Potent, Selective Small Molecule Inhibitor of IκB Kinase 2, TPCA-1 (2-[(Aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide), Occurs via Reduction of Proinflammatory Cytokines and Antigen-Induced T Cell Proliferation

The Journal of pharmacology and experimental therapeutics, 2005-01, Vol.312 (1), p.373-381

2005

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Targeted Disruption of the Endothelin-B-Receptor Gene Attenuates Inflammatory Nociception and Cutaneous Inflammation in Mice

Journal of cardiovascular pharmacology, 2000, Vol.36 Suppl 1 (5 Suppl 1), p.S78-S81

2000

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Targeted Disruption of the Endothelin-B-Receptor Gene Attenuates Inflammatory Nociception and Cutaneous Inflammation in Mice

Journal of cardiovascular pharmacology, 2000, Vol.36 (5 Suppl 1), p.S78-S81

2000

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The Identification of a Novel Phosphodiesterase 4 Inhibitor, 1-Ethyl-5-{5-[(4-methyl-1-piperazinyl)methyl]-1,3,4-oxadiazol-2-yl}- N -(tetrahydro-2 H -pyran-4-yl)-1 H -pyrazolo[3,4- b ]pyridin-4-amine (EPPA-1), with Improved Therapeutic Index using Pica Feeding in Rats as a Measure of Emetogenicity

The Journal of pharmacology and experimental therapeutics, 2009-09, Vol.330 (3), p.922-931

2009

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Attenuation of murine collagen-induced arthritis by a novel, potent, selective small molecule inhibitor of IkappaB Kinase 2, TPCA-1 (2-[(aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide), occurs via reduction of proinflammatory cytokines and antigen-induced T cell Proliferation

The Journal of pharmacology and experimental therapeutics, 2005-01, Vol.312 (1), p.373

2005

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Interim Estimates of 2023-24 Seasonal Influenza Vaccine Effectiveness - United States

MMWR. Morbidity and mortality weekly report, 2024-02, Vol.73 (8), p.168-174

2024

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World Insurance Trends

1, 1959

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Chile

World Insurance Trends, 2016, p.402

2016

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Spain

World Insurance Trends, 2016, p.603

2016

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Canadian Developments in Hospital Insurance

World Insurance Trends, 2016, p.257-268

1178.50, 2016

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Continental Europe

World Insurance Trends, 2016, p.17-26

1178.50, 2016

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The German Experience with Health Insurance

World Insurance Trends, 2016, p.230-237

1178.50, 2016

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Indonesia

World Insurance Trends, 2016, p.521

2016

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Latin America

World Insurance Trends, 2016, p.59

2016

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The Community Association Approach to Health Insurance in the United States

World Insurance Trends, 2016, p.238-244

1178.50, 2016

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South Africa

World Insurance Trends, 2016, p.593

2016

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(Western) Germany

World Insurance Trends, 2016, p.485

2016

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Brazil

World Insurance Trends, 2016, p.376

2016

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Pica in Rats as a Preclinical Model of Emesis

The identification of a novel phosphodiesterase 4 inhibitor, 1-ethyl-5-{5-[(4-methyl-1-piperazinyl)methyl]-1,3,4-oxadiazol-2-yl}-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-b]pyridin-4-amine (EPPA-1), with improved therapeutic index using pica feeding in rats as a measure of emetogenicity

Rapid Lipid Mediator Profiling by Convergence Chromatography-MS/MS

GSK356278, a potent, selective, brain-penetrant phosphodiesterase 4 inhibitor that demonstrates anxiolytic and cognition-enhancing effects without inducing side effects in preclinical species

Prostaglandin Metabolites Analysis in Urine by LC-MS/MS

Inhibition of Invariant Chain Processing, Antigen-Induced Proliferative Responses, and the Development of Collagen-Induced Arthritis and Experimental Autoimmune Encephalomyelitis by a Small Molecule Cysteine Protease Inhibitor

Endothelin B Receptor Modulates Inflammatory Pain and Cutaneous Inflammation

Attenuation of Murine Collagen-Induced Arthritis by a Novel, Potent, Selective Small Molecule Inhibitor of IκB Kinase 2, TPCA-1 (2-[(Aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide), Occurs via Reduction of Proinflammatory Cytokines and Antigen-Induced T Cell Proliferation

Targeted Disruption of the Endothelin-B-Receptor Gene Attenuates Inflammatory Nociception and Cutaneous Inflammation in Mice

Targeted Disruption of the Endothelin-B-Receptor Gene Attenuates Inflammatory Nociception and Cutaneous Inflammation in Mice

The Identification of a Novel Phosphodiesterase 4 Inhibitor, 1-Ethyl-5-{5-[(4-methyl-1-piperazinyl)methyl]-1,3,4-oxadiazol-2-yl}- N -(tetrahydro-2 H -pyran-4-yl)-1 H -pyrazolo[3,4- b ]pyridin-4-amine (EPPA-1), with Improved Therapeutic Index using Pica Feeding in Rats as a Measure of Emetogenicity

Attenuation of murine collagen-induced arthritis by a novel, potent, selective small molecule inhibitor of IkappaB Kinase 2, TPCA-1 (2-[(aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide), occurs via reduction of proinflammatory cytokines and antigen-induced T cell Proliferation

Interim Estimates of 2023-24 Seasonal Influenza Vaccine Effectiveness - United States

World Insurance Trends

Chile

Spain

Canadian Developments in Hospital Insurance

Continental Europe

The German Experience with Health Insurance

Indonesia

Latin America

The Community Association Approach to Health Insurance in the United States

South Africa

(Western) Germany

Brazil

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