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Molecular Pathways: ROS1 Fusion Proteins in Cancer

Clinical cancer research, 2013-08, Vol.19 (15), p.4040-4045

2013

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The TAM family: phosphatidylserine sensing receptor tyrosine kinases gone awry in cancer

Nature reviews. Cancer, 2014-12, Vol.14 (12), p.769-785

2014

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Comparison of Molecular Testing Modalities for Detection of ROS1 Rearrangements in a Cohort of Positive Patient Samples

Journal of thoracic oncology, 2018-10, Vol.13 (10), p.1474-1482

2018

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DNA-Based versus RNA-Based Detection of MET Exon 14 Skipping Events in Lung Cancer

Journal of thoracic oncology, 2019-04, Vol.14 (4), p.737-741

2019

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Resistance Mechanisms to Targeted Therapies in ROS1 + and ALK + Non-small Cell Lung Cancer

Clinical cancer research, 2018-07, Vol.24 (14), p.3334-3347

2018

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Identifying and Targeting ROS1 Gene Fusions in Non―Small Cell Lung Cancer

Clinical cancer research, 2012-09, Vol.18 (17), p.4570-4579

2012

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Resistance to ROS1 inhibition mediated by EGFR pathway activation in non-small cell lung cancer

PloS one, 2013-12, Vol.8 (12), p.e82236

2013

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Clinical Utility of Cell-Free DNA for the Detection of ALK Fusions and Genomic Mechanisms of ALK Inhibitor Resistance in Non-Small Cell Lung Cancer

Clinical cancer research, 2018-06, Vol.24 (12), p.2758-2770

2018

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EGFR Mediates Responses to Small-Molecule Drugs Targeting Oncogenic Fusion Kinases

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13), p.3551-3563

2017

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Radiation induces acute alterations in neuronal function

PloS one, 2012-05, Vol.7 (5), p.e37677-e37677

2012

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Targeted fusion analysis can aid in the classification and treatment of pediatric glioma, ependymoma, and glioneuronal tumors

Pediatric blood & cancer, 2020-01, Vol.67 (1), p.e28028-n/a

2020

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Dual mechanism of a natural CaMKII inhibitor

Molecular biology of the cell, 2007-12, Vol.18 (12), p.5024-5033

2007

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Small Molecule Inhibition of MERTK Is Efficacious in Non-Small Cell Lung Cancer Models Independent of Driver Oncogene Status

Molecular cancer therapeutics, 2015-09, Vol.14 (9), p.2014-2022

2015

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Clinical and molecular features of subungual melanomas are site-specific and distinct from acral melanomas

Melanoma research, 2020-12, Vol.30 (6), p.562-573

2020

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Validation of a Targeted RNA Sequencing Assay for Kinase Fusion Detection in Solid Tumors

The Journal of molecular diagnostics : JMD, 2017-09, Vol.19 (5), p.682-696

2017

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L2086F Mutant ROS1-Rearranged NSCLC Resistant to Repotrectinib Responds to Cabozantinib: A Case Report

JTO clinical and research reports, 2024-07, Vol.5 (7), p.100673, Article 100673

2024

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Evolution of acquired resistance in a ROS1+ KRAS G12C+ NSCLC through the MAPK pathway

NPJ precision oncology, 2023-01, Vol.7 (1), p.9-9, Article 9

2023

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Mutational Signatures in Cancer: Laboratory Considerations and Emerging Applications

The Journal of molecular diagnostics : JMD, 2023-11, Vol.25 (11), p.790-795

2023

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Chk1 inhibition and Wee1 inhibition combine synergistically to impede cellular proliferation

Cancer biology & therapy, 2011-11, Vol.12 (9), p.788-796

2011

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MET Copy Number as a Secondary Driver of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Resistance in EGFR-Mutant Non-Small-Cell Lung Cancer

Journal of clinical oncology, 2019-04, Vol.37 (11), p.855-857

2019

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Wake Up and Smell the Fusions: Single-Modality Molecular Testing Misses Drivers

Clinical cancer research, 2019-08, Vol.25 (15), p.4586-4588

2019

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Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer

Nature medicine, 2013-11, Vol.19 (11), p.1469-1472

2013

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Tumor-Infiltrating T Cells and the PD-1 Checkpoint Pathway in Advanced Differentiated and Anaplastic Thyroid Cancer

The journal of clinical endocrinology and metabolism, 2016-07, Vol.101 (7), p.2863-2873

2016

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MET Exon 14 Skipping Mutations in Non-Small-Cell Lung Cancer: An Overview of Biology, Clinical Outcomes, and Testing Considerations

JCO precision oncology, 2021, Vol.5 (5), p.653-663

2021

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Molecular Pathways: ROS1 Fusion Proteins in Cancer

The TAM family: phosphatidylserine sensing receptor tyrosine kinases gone awry in cancer

Comparison of Molecular Testing Modalities for Detection of ROS1 Rearrangements in a Cohort of Positive Patient Samples

DNA-Based versus RNA-Based Detection of MET Exon 14 Skipping Events in Lung Cancer

Resistance Mechanisms to Targeted Therapies in ROS1 + and ALK + Non-small Cell Lung Cancer

Identifying and Targeting ROS1 Gene Fusions in Non―Small Cell Lung Cancer

Resistance to ROS1 inhibition mediated by EGFR pathway activation in non-small cell lung cancer

Clinical Utility of Cell-Free DNA for the Detection of ALK Fusions and Genomic Mechanisms of ALK Inhibitor Resistance in Non-Small Cell Lung Cancer

Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors

EGFR Mediates Responses to Small-Molecule Drugs Targeting Oncogenic Fusion Kinases

Radiation induces acute alterations in neuronal function

Targeted fusion analysis can aid in the classification and treatment of pediatric glioma, ependymoma, and glioneuronal tumors

Dual mechanism of a natural CaMKII inhibitor

Small Molecule Inhibition of MERTK Is Efficacious in Non-Small Cell Lung Cancer Models Independent of Driver Oncogene Status

Clinical and molecular features of subungual melanomas are site-specific and distinct from acral melanomas

Validation of a Targeted RNA Sequencing Assay for Kinase Fusion Detection in Solid Tumors

L2086F Mutant ROS1-Rearranged NSCLC Resistant to Repotrectinib Responds to Cabozantinib: A Case Report

Evolution of acquired resistance in a ROS1+ KRAS G12C+ NSCLC through the MAPK pathway

Mutational Signatures in Cancer: Laboratory Considerations and Emerging Applications

Chk1 inhibition and Wee1 inhibition combine synergistically to impede cellular proliferation

MET Copy Number as a Secondary Driver of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Resistance in EGFR-Mutant Non-Small-Cell Lung Cancer

Wake Up and Smell the Fusions: Single-Modality Molecular Testing Misses Drivers

Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer

Tumor-Infiltrating T Cells and the PD-1 Checkpoint Pathway in Advanced Differentiated and Anaplastic Thyroid Cancer

MET Exon 14 Skipping Mutations in Non-Small-Cell Lung Cancer: An Overview of Biology, Clinical Outcomes, and Testing Considerations

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