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Discovery of Ketone-Based Covalent Inhibitors of Coronavirus 3CL Proteases for the Potential Therapeutic Treatment of COVID-19

Journal of medicinal chemistry, 2020-11, Vol.63 (21), p.12725-12747

2020

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Dihydroxyphenylisoindoline Amides as Orally Bioavailable Inhibitors of the Heat Shock Protein 90 (Hsp90) Molecular Chaperone

Journal of medicinal chemistry, 2010-01, Vol.53 (1), p.499-503

2010

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Dihydroxylphenyl amides as inhibitors of the Hsp90 molecular chaperone

Bioorganic & medicinal chemistry, 2008-12, Vol.18 (23), p.6273-6278

2008

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Crystal Structure of the Ribonuclease H Domain of HIV-1 Reverse Transcriptase

Science (American Association for the Advancement of Science), 1991-04, Vol.252 (5002), p.88-95

1991

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Putting the sensory individual at the centre of architectural design

Architectural science review, 2024-10, p.1-10

2024

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Can AI Predict the Magnitude and Direction of Ortho-K Contact Lens Decentration to Limit Induced HOAs and Astigmatism?

Journal of clinical medicine, 2024-09, Vol.13 (18), p.5420

2024

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Crystal structures of recombinant human dihydrofolate reductase complexed with folate and 5-deazafolate

Biochemistry (Easton), 1990-10, Vol.29 (40), p.9467-9479

1990

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Structure-Based Design and Synthesis of Substituted 2-Butanols as Nonpeptidic Inhibitors of HIV Protease: Secondary Amide Series

Journal of medicinal chemistry, 1996-07, Vol.39 (14), p.2781-2794

1996

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Viracept (Nelfinavir Mesylate, AG1343): A Potent, Orally Bioavailable Inhibitor of HIV-1 Protease

Journal of medicinal chemistry, 1997-11, Vol.40 (24), p.3979-3985

1997

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Bis Tertiary Amide Inhibitors of the HIV-1 Protease Generated via Protein Structure-Based Iterative Design

Journal of medicinal chemistry, 1996-07, Vol.39 (14), p.2795-2811

1996

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Crystal structure of chicken liver dihydrofolate reductase complexed with NADP+ and biopterin

Biochemistry (Easton), 1992-08, Vol.31 (32), p.7264-7273

1992

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Protein Structure-Based Design of Potent Orally Bioavailable, Nonpeptide Inhibitors of Human Immunodeficiency Virus Protease

Proceedings of the National Academy of Sciences - PNAS, 1995-04, Vol.92 (8), p.3298-3302

1995

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2.3 Å crystal structure of the catalytic domain of DNA polymerase β

Cell, 1994-03, Vol.76 (6), p.1123-1133

1994

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Crystal structures of chicken liver dihydrofolate reductase: Binary thioNADP+ and ternary thioNADP+.cntdot.biopterin complexes

Biochemistry (Easton), 1993-07, Vol.32 (27), p.6855-6862

1993

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Structure and functional relationships in human pur H

Advances in experimental medicine and biology, 1998, Vol.431, p.221

1998

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Proteolytic release and crystallization of the RNase H domain of human immunodeficiency virus type 1 reverse transcriptase

The Journal of biological chemistry, 1991-08, Vol.266 (22), p.14697-14702

1991

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Crystal structures of chicken liver dihydrofolate reductase : binary ThioNADP+ and ternary ThioNADP+..biopterin complexes

Biochemistry (Easton), 1993-07, Vol.32 (27), p.6855-6862

1993

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ITERATIVE PROTEIN STRUCTURE-BASED DRUG DESIGN AND SYNTHESIS OF HIV PROTEASE INHIBITORS

European journal of medicinal chemistry, 1995, Vol.30, p.201s-214s

1995

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Structure-based drug design of nonpeptidic P2 substituents for HIV-1 protease inhibitors

Bioorganic & medicinal chemistry letters, 1995-04, Vol.5 (7), p.727-732

1995

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Structure-based drug design of nonpeptidic P 2 substituents for HIV-1 protease inhibitors

Bioorganic & medicinal chemistry letters, 1995-04, Vol.5 (7), p.727-732

1995

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Crystal structures of recombinant human dihydrofolate reductase, chicken liver dihydrofolate reductase, and a site-directed mutant of cytochrome c peroxidase

Davies, Jay Franklin

1991

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The best business writing 2012

1, 2012

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What is the concentration of hydrogen peroxide in blood and plasma?

Archives of biochemistry and biophysics, 2016-08, Vol.603, p.48-53

2016

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Oxidative stress response and Nrf2 signaling in aging

Free radical biology & medicine, 2015-11, Vol.88 (Pt B), p.314-336

2015

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Effects of carbon monoxide on cardio-respiratory performances in simulated cycling

Davies, Cindy Jay

1979

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Discovery of Ketone-Based Covalent Inhibitors of Coronavirus 3CL Proteases for the Potential Therapeutic Treatment of COVID-19

Dihydroxyphenylisoindoline Amides as Orally Bioavailable Inhibitors of the Heat Shock Protein 90 (Hsp90) Molecular Chaperone

Dihydroxylphenyl amides as inhibitors of the Hsp90 molecular chaperone

Crystal Structure of the Ribonuclease H Domain of HIV-1 Reverse Transcriptase

Putting the sensory individual at the centre of architectural design

Can AI Predict the Magnitude and Direction of Ortho-K Contact Lens Decentration to Limit Induced HOAs and Astigmatism?

Crystal structures of recombinant human dihydrofolate reductase complexed with folate and 5-deazafolate

Structure-Based Design and Synthesis of Substituted 2-Butanols as Nonpeptidic Inhibitors of HIV Protease: Secondary Amide Series

Viracept (Nelfinavir Mesylate, AG1343): A Potent, Orally Bioavailable Inhibitor of HIV-1 Protease

Bis Tertiary Amide Inhibitors of the HIV-1 Protease Generated via Protein Structure-Based Iterative Design

Crystal structure of chicken liver dihydrofolate reductase complexed with NADP+ and biopterin

Protein Structure-Based Design of Potent Orally Bioavailable, Nonpeptide Inhibitors of Human Immunodeficiency Virus Protease

2.3 Å crystal structure of the catalytic domain of DNA polymerase β

Crystal structures of chicken liver dihydrofolate reductase: Binary thioNADP+ and ternary thioNADP+.cntdot.biopterin complexes

Structure and functional relationships in human pur H

Proteolytic release and crystallization of the RNase H domain of human immunodeficiency virus type 1 reverse transcriptase

Crystal structures of chicken liver dihydrofolate reductase : binary ThioNADP+ and ternary ThioNADP+..biopterin complexes

ITERATIVE PROTEIN STRUCTURE-BASED DRUG DESIGN AND SYNTHESIS OF HIV PROTEASE INHIBITORS

Structure-based drug design of nonpeptidic P2 substituents for HIV-1 protease inhibitors

Structure-based drug design of nonpeptidic P 2 substituents for HIV-1 protease inhibitors

Crystal structures of recombinant human dihydrofolate reductase, chicken liver dihydrofolate reductase, and a site-directed mutant of cytochrome c peroxidase

The best business writing 2012

What is the concentration of hydrogen peroxide in blood and plasma?

Oxidative stress response and Nrf2 signaling in aging

Effects of carbon monoxide on cardio-respiratory performances in simulated cycling

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