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Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing

Nature communications, 2017-08, Vol.8 (1), p.268-11, Article 268

2017

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Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms

Leukemia, 2014-02, Vol.28 (2), p.384-390

2014

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Prediction of outcome in newly diagnosed myeloma: a meta-analysis of the molecular profiles of 1905 trial patients

Leukemia, 2018-01, Vol.32 (1), p.102-110

2018

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Single-cell genetic analysis reveals the composition of initiating clones and phylogenetic patterns of branching and parallel evolution in myeloma

Leukemia, 2014-08, Vol.28 (8), p.1705-1715

2014

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A novel prognostic model in myeloma based on co-segregating adverse FISH lesions and the ISS: analysis of patients treated in the MRC Myeloma IX trial

Leukemia, 2012-02, Vol.26 (2), p.349-355

2012

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Optimizing the use of lenalidomide in relapsed or refractory multiple myeloma: consensus statement

Leukemia, 2011-05, Vol.25 (5), p.749-760

2011

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Adherence of multiple myeloma cells to bone marrow stromal cells upregulates vascular endothelial growth factor secretion: therapeutic applications

Leukemia, 2001-12, Vol.15 (12), p.1950-1961

2001

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Clinical value of molecular subtyping multiple myeloma using gene expression profiling

Leukemia, 2016-02, Vol.30 (2), p.423-430

2016

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Second malignancies in the context of lenalidomide treatment: an analysis of 2732 myeloma patients enrolled to the Myeloma XI trial

Blood cancer journal (New York), 2016-12, Vol.6 (12), p.e506-e506

2016

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Progression free survival of myeloma patients who become IFE-negative correlates with the detection of residual monoclonal free light chain (FLC) by mass spectrometry

Blood cancer journal (New York), 2024-03, Vol.14 (1), p.50-50, Article 50

2024

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Targeting heat shock protein 72 enhances Hsp90 inhibitor-induced apoptosis in myeloma

Leukemia, 2010-10, Vol.24 (10), p.1804-1807

2010

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Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy

Blood, 2000-11, Vol.96 (9), p.2943-2950

2000

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A TC classification-based predictor for multiple myeloma using multiplexed real-time quantitative PCR

Leukemia, 2013-08, Vol.27 (8), p.1754-1757

2013

Volltextzugriff (PDF)

Combination of flow cytometry and functional imaging for monitoring of residual disease in myeloma

Leukemia, 2019-07, Vol.33 (7), p.1713-1722

2019

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Whole-body diffusion-weighted MRI: a new gold standard for assessing disease burden in patients with multiple myeloma?

Leukemia, 2016-06, Vol.30 (6), p.1446-1448

2016

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An early CT-diagnosis-based treatment strategy for invasive fungal infection in allogeneic transplant recipients using caspofungin first line: an effective strategy with low mortality

Bone marrow transplantation (Basingstoke), 2009-07, Vol.44 (1), p.51-56

2009

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Expert panel consensus statement on the optimal use of pomalidomide in relapsed and refractory multiple myeloma

Leukemia, 2014-08, Vol.28 (8), p.1573-1585

2014

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Cyclophosphamide, thalidomide, and dexamethasone as induction therapy for newly diagnosed multiple myeloma patients destined for autologous stem-cell transplantation: MRC Myeloma IX randomized trial results

Haematologica (Roma), 2012-03, Vol.97 (3), p.442-450

2012

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DangER: protein ovERload. Targeting protein degradation to treat myeloma

Haematologica (Roma), 2012-08, Vol.97 (8), p.1119-1130

2012

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Assessing response of myeloma bone disease with diffusion-weighted MRI

British journal of radiology, 2012-12, Vol.85 (1020), p.e1198-e1203

2012

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Mutations in CRBN and other cereblon pathway genes are infrequently associated with acquired resistance to immunomodulatory drugs

Leukemia, 2021-10, Vol.35 (10), p.3017-3020

2021

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Translocations at 8q24 juxtapose MYC with genes that harbor superenhancers resulting in overexpression and poor prognosis in myeloma patients

Blood cancer journal (New York), 2014-03, Vol.4 (3), p.e191-e191

2014

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Hyperhaploidy is a novel high-risk cytogenetic subgroup in multiple myeloma

Leukemia, 2017-03, Vol.31 (3), p.637-644

2017

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Overexpression of EZH2 in multiple myeloma is associated with poor prognosis and dysregulation of cell cycle control

Blood cancer journal (New York), 2017-03, Vol.7 (3), p.e549-e549

2017

Volltextzugriff (PDF)

Myeloma aetiology and epidemiology

Biomedicine & Pharmacotherapy, 2002-07, Vol.56 (5), p.223-234

2002

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Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing

Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms

Prediction of outcome in newly diagnosed myeloma: a meta-analysis of the molecular profiles of 1905 trial patients

Single-cell genetic analysis reveals the composition of initiating clones and phylogenetic patterns of branching and parallel evolution in myeloma

A novel prognostic model in myeloma based on co-segregating adverse FISH lesions and the ISS: analysis of patients treated in the MRC Myeloma IX trial

Optimizing the use of lenalidomide in relapsed or refractory multiple myeloma: consensus statement

Adherence of multiple myeloma cells to bone marrow stromal cells upregulates vascular endothelial growth factor secretion: therapeutic applications

Clinical value of molecular subtyping multiple myeloma using gene expression profiling

Second malignancies in the context of lenalidomide treatment: an analysis of 2732 myeloma patients enrolled to the Myeloma XI trial

Progression free survival of myeloma patients who become IFE-negative correlates with the detection of residual monoclonal free light chain (FLC) by mass spectrometry

Targeting heat shock protein 72 enhances Hsp90 inhibitor-induced apoptosis in myeloma

Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy

A TC classification-based predictor for multiple myeloma using multiplexed real-time quantitative PCR

Combination of flow cytometry and functional imaging for monitoring of residual disease in myeloma

Whole-body diffusion-weighted MRI: a new gold standard for assessing disease burden in patients with multiple myeloma?

An early CT-diagnosis-based treatment strategy for invasive fungal infection in allogeneic transplant recipients using caspofungin first line: an effective strategy with low mortality

Expert panel consensus statement on the optimal use of pomalidomide in relapsed and refractory multiple myeloma

Cyclophosphamide, thalidomide, and dexamethasone as induction therapy for newly diagnosed multiple myeloma patients destined for autologous stem-cell transplantation: MRC Myeloma IX randomized trial results

DangER: protein ovERload. Targeting protein degradation to treat myeloma

Assessing response of myeloma bone disease with diffusion-weighted MRI

Mutations in CRBN and other cereblon pathway genes are infrequently associated with acquired resistance to immunomodulatory drugs

Translocations at 8q24 juxtapose MYC with genes that harbor superenhancers resulting in overexpression and poor prognosis in myeloma patients

Hyperhaploidy is a novel high-risk cytogenetic subgroup in multiple myeloma

Overexpression of EZH2 in multiple myeloma is associated with poor prognosis and dysregulation of cell cycle control

Myeloma aetiology and epidemiology

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