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A roadmap to target interleukin-6 in osteoarthritis

Rheumatology (Oxford, England), 2020-10, Vol.59 (10), p.2681-2694

2020

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Increase in ALK1/ALK5 Ratio as a Cause for Elevated MMP-13 Expression in Osteoarthritis in Humans and Mice

The Journal of immunology (1950), 2009-06, Vol.182 (12), p.7937-7945

2009

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Unravelling osteoarthritis-related synovial fibrosis: a step closer to solving joint stiffness

Rheumatology (Oxford, England), 2015-11, Vol.54 (11), p.1954-1963

2015

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Activin Receptor-Like Kinase Receptors ALK5 and ALK1 Are Both Required for TGFβ-Induced Chondrogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells

PloS one, 2015-12, Vol.10 (12), p.e0146124-e0146124

2015

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Cripto favors chondrocyte hypertrophy via TGF‐β SMAD1/5 signaling during development of osteoarthritis

The Journal of pathology, 2021-11, Vol.255 (3), p.330-342

2021

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The alarmins S100A8 and S100A9 mediate acute pain in experimental synovitis

Arthritis research & therapy, 2020-08, Vol.22 (1), p.199-199, Article 199

2020

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Sclerostin antibody enhances implant osseointegration in bone with Col1a1 mutation

Bone (New York, N.Y.), 2024-09, Vol.186, p.117167-117167, Article 117167

2024

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Catabolic factors and osteoarthritis-conditioned medium inhibit chondrogenesis of human mesenchymal stem cells

Tissue engineering. Part A, 2012-01, Vol.18 (1-2), p.45-54

2012

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Separating friend from foe: Inhibition of TGF-β-induced detrimental SMAD1/5/9 phosphorylation while maintaining protective SMAD2/3 signaling in OA chondrocytes

Osteoarthritis and cartilage, 2023-11, Vol.31 (11), p.1481-1490

2023

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SMAD3 and SMAD4 have a more dominant role than SMAD2 in TGFβ-induced chondrogenic differentiation of bone marrow-derived mesenchymal stem cells

Scientific reports, 2017-02, Vol.7 (1), p.43164-43164, Article 43164

2017

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Early pain in females is linked to late pathological features in murine experimental osteoarthritis

PeerJ (San Francisco, CA), 2023-06, Vol.11, p.e15482-e15482, Article e15482

2023

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A role for age-related changes in TGFβ signaling in aberrant chondrocyte differentiation and osteoarthritis

Arthritis research & therapy, 2010-01, Vol.12 (1), p.201-201

2010

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Innate Immunity at the Core of Sex Differences in Osteoarthritic Pain?

Frontiers in pharmacology, 2022-05, Vol.13, p.881500-881500

2022

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Canonical Wnt signaling skews TGF-β signaling in chondrocytes towards signaling via ALK1 and Smad 1/5/8

Cellular signalling, 2014-05, Vol.26 (5), p.951-958

2014

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Milk extracellular vesicles accelerate osteoblastogenesis but impair bone matrix formation

The Journal of nutritional biochemistry, 2016-04, Vol.30, p.74-84

2016

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Sex Differences in Pain Sensitivity in a Dutch Cohort: Cross-Sectional and Web-Based Multidimensional Study

Journal of medical Internet research, 2024-08, Vol.26 (9), p.e53926

2024

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Innate Immunity and Sex: Distinct Inflammatory Profiles Associated with Murine Pain in Acute Synovitis

Cells (Basel, Switzerland), 2023-07, Vol.12 (14), p.1913

2023

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Interleukin 1 β-induced SMAD2/3 linker modifications are TAK1 dependent and delay TGFβ signaling in primary human mesenchymal stem cells

Cellular signalling, 2017-12, Vol.40, p.190-199

2017

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Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodeling

Arthritis research & therapy, 2007-01, Vol.9 (5), p.R102-R102, Article R102

2007

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Identification of TGFβ-related genes regulated in murine osteoarthritis and chondrocyte hypertrophy by comparison of multiple microarray datasets

Bone (New York, N.Y.), 2018-11, Vol.116, p.67-77

2018

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TGF beta-induced cartilage repair is maintained but fibrosis is blocked in the presence of Smad7

Arthritis research & therapy, 2006-01, Vol.8 (3), p.R65-R65, Article R65

2006

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Growth factors that drive aggrecan synthesis in healthy articular cartilage. Role for transforming growth factor-β?

Osteoarthritis and cartilage open, 2024-06, Vol.6 (2), p.100459-100459, Article 100459

2024

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IL37 dampens the IL1β-induced catabolic status of human OA chondrocytes

Rheumatology (Oxford, England), 2017-03, Vol.56 (3), p.351-361

2017

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Treatment of collagenase-induced osteoarthritis with a viral vector encoding TSG-6 results in ectopic bone formation

PeerJ (San Francisco, CA), 2018-05, Vol.6, p.e4771-e4771, Article e4771

2018

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Gas6/Axl Axis Activation Dampens the Inflammatory Response in Osteoarthritic Fibroblast-like Synoviocytes and Synovial Explants

Pharmaceuticals (Basel, Switzerland), 2023-05, Vol.16 (5), p.703

2023

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A roadmap to target interleukin-6 in osteoarthritis

Increase in ALK1/ALK5 Ratio as a Cause for Elevated MMP-13 Expression in Osteoarthritis in Humans and Mice

Unravelling osteoarthritis-related synovial fibrosis: a step closer to solving joint stiffness

Activin Receptor-Like Kinase Receptors ALK5 and ALK1 Are Both Required for TGFβ-Induced Chondrogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells

Cripto favors chondrocyte hypertrophy via TGF‐β SMAD1/5 signaling during development of osteoarthritis

The alarmins S100A8 and S100A9 mediate acute pain in experimental synovitis

Sclerostin antibody enhances implant osseointegration in bone with Col1a1 mutation

Catabolic factors and osteoarthritis-conditioned medium inhibit chondrogenesis of human mesenchymal stem cells

Separating friend from foe: Inhibition of TGF-β-induced detrimental SMAD1/5/9 phosphorylation while maintaining protective SMAD2/3 signaling in OA chondrocytes

SMAD3 and SMAD4 have a more dominant role than SMAD2 in TGFβ-induced chondrogenic differentiation of bone marrow-derived mesenchymal stem cells

Early pain in females is linked to late pathological features in murine experimental osteoarthritis

A role for age-related changes in TGFβ signaling in aberrant chondrocyte differentiation and osteoarthritis

Innate Immunity at the Core of Sex Differences in Osteoarthritic Pain?

Canonical Wnt signaling skews TGF-β signaling in chondrocytes towards signaling via ALK1 and Smad 1/5/8

Milk extracellular vesicles accelerate osteoblastogenesis but impair bone matrix formation

Sex Differences in Pain Sensitivity in a Dutch Cohort: Cross-Sectional and Web-Based Multidimensional Study

Innate Immunity and Sex: Distinct Inflammatory Profiles Associated with Murine Pain in Acute Synovitis

Interleukin 1 β-induced SMAD2/3 linker modifications are TAK1 dependent and delay TGFβ signaling in primary human mesenchymal stem cells

Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodeling

Identification of TGFβ-related genes regulated in murine osteoarthritis and chondrocyte hypertrophy by comparison of multiple microarray datasets

TGF beta-induced cartilage repair is maintained but fibrosis is blocked in the presence of Smad7

Growth factors that drive aggrecan synthesis in healthy articular cartilage. Role for transforming growth factor-β?

IL37 dampens the IL1β-induced catabolic status of human OA chondrocytes

Treatment of collagenase-induced osteoarthritis with a viral vector encoding TSG-6 results in ectopic bone formation

Gas6/Axl Axis Activation Dampens the Inflammatory Response in Osteoarthritic Fibroblast-like Synoviocytes and Synovial Explants

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