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Ectopic expression of methionine aminopeptidase-2 causes cell transformation and stimulates proliferation

Oncogene, 2008-06, Vol.27 (28), p.3967-3976

2008

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Synergistic antileukemic effects between ABT-869 and chemotherapy involve downregulation of cell cycle-regulated genes and c-Mos-mediated MAPK pathway

Leukemia, 2008-01, Vol.22 (1), p.138-146

2008

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Discovery of Potent Nonpeptide Inhibitors of Stromelysin Using SAR by NMR

Journal of the American Chemical Society, 1997-06, Vol.119 (25), p.5818-5827

1997

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Differential protein acetylation induced by novel histone deacetylase inhibitors

Biochemical and biophysical research communications, 2004-12, Vol.325 (3), p.683-690

2004

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Role of Class I and Class II histone deacetylases in carcinoma cells using siRNA

Biochemical and biophysical research communications, 2003-10, Vol.310 (2), p.529-536

2003

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Analysis of two matrix metalloproteinase inhibitors and their metabolites for induction of phospholipidosis in rat and human hepatocytes

Biochemical pharmacology, 2001-12, Vol.62 (12), p.1661-1673

2001

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Synthetic inhibitor of matrix metalloproteases decreases tumor growth and metastases in a syngeneic model of rat prostate cancer in vivo

International journal of cancer, 2000-07, Vol.87 (2), p.276-282

2000

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Phenoxyphenyl Sulfone N-Formylhydroxylamines (Retrohydroxamates) as Potent, Selective, Orally Bioavailable Matrix Metalloproteinase Inhibitors

Journal of medicinal chemistry, 2002-01, Vol.45 (1), p.219-232

2002

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The design, synthesis, and structure-activity relationships of a series of macrocyclic MMP inhibitors

Bioorganic & medicinal chemistry letters, 1998-08, Vol.8 (16), p.2087-2092

1998

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N-(Acyloxyalkyl)pyridinium Salts as Soluble Prodrugs of a Potent Platelet Activating Factor Antagonist

Journal of medicinal chemistry, 1994-12, Vol.37 (26), p.4423-4429

1994

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Aryl ketones as novel replacements for the C-terminal amide bond of succinyl hydroxamate MMP inhibitors

Bioorganic & medicinal chemistry letters, 1998-11, Vol.8 (22), p.3251-3256

1998

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Pharmacology of ABT-491, a highly potent platelet-activating factor receptor antagonist

European journal of pharmacology, 1997-04, Vol.325 (1), p.69-80

1997

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Biaryl Ether Retrohydroxamates as Potent, Long-lived, Orally Bioavailable MMP Inhibitors

Bioorganic & medicinal chemistry letters, 2001-06, Vol.11 (12), p.1553-1556

2001

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Properties of ABT-299, a prodrug of A-85783, a highly potent platelet activating factor receptor antagonist

The Journal of pharmacology and experimental therapeutics, 1996-06, Vol.277 (3), p.1595

1996

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ABT-491, a highly potent and selective PAF antagonist, inhibits nasal vascular permeability associated with experimental allergic rhinitis in brown Norway rats

Inflammation research, 1997-08, Vol.46 Suppl 2 (2), p.S133-134

1997

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Gene expression profiling of multiple histone deacetylase (HDAC) inhibitors: defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines

Molecular cancer therapeutics, 2003-02, Vol.2 (2), p.151-163

2003

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Small atrial natriuretic peptide analogs: design, synthesis, and structural requirements for guanylate cyclase activation

Journal of medicinal chemistry, 1992-03, Vol.35 (5), p.808-816

1992

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Atrial peptides induce mast cell histamine release

Peptides (New York, N.Y. : 1980), 1990-09, Vol.11 (5), p.1003-1007

1990

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Characterization of Matrix Metalloproteinase Inhibitors: Angiogenesis and Tumor Models

Current Protocols in Pharmacology, 2001-08, Vol.13 (1), p.5.23.1-5.23.12

2001

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Characterization of Matrix Metalloproteinase Inhibitors: Enzymatic Assays

Current Protocols in Pharmacology, 2001-08, Vol.13 (1), p.3.7.1-3.7.13

2001

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The role of platelet-activating factor (PAF) and the efficacy of ABT-491, a highly potent and selective PAF antagonist, in experimental allergic rhinitis

The Journal of pharmacology and experimental therapeutics, 1998-01, Vol.284 (1), p.83

1998

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Thienopyrimidine Ureas as Novel and Potent Multitargeted Receptor Tyrosine Kinase Inhibitors

Journal of medicinal chemistry, 2005-09, Vol.48 (19), p.6066-6083

2005

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Di-tert-butyl N-acylimidodicarbonates as isolable acylating agents: mild conversion of primary carboxamides to substituted amides

Journal of organic chemistry, 1991-08, Vol.56 (18), p.5482-5485

1991

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Broad spectrum matrix metalloproteinase inhibitors : An examination of succinamide hydroxamate inhibitors with p1 Cα gem-disubstitution

Bioorganic & medicinal chemistry letters, 1998-06, Vol.8 (12), p.1443-1448

1998

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Ectopic expression of methionine aminopeptidase-2 causes cell transformation and stimulates proliferation

Synergistic antileukemic effects between ABT-869 and chemotherapy involve downregulation of cell cycle-regulated genes and c-Mos-mediated MAPK pathway

Discovery of Potent Nonpeptide Inhibitors of Stromelysin Using SAR by NMR

Differential protein acetylation induced by novel histone deacetylase inhibitors

Role of Class I and Class II histone deacetylases in carcinoma cells using siRNA

Analysis of two matrix metalloproteinase inhibitors and their metabolites for induction of phospholipidosis in rat and human hepatocytes

Synthetic inhibitor of matrix metalloproteases decreases tumor growth and metastases in a syngeneic model of rat prostate cancer in vivo

Phenoxyphenyl Sulfone N-Formylhydroxylamines (Retrohydroxamates) as Potent, Selective, Orally Bioavailable Matrix Metalloproteinase Inhibitors

The design, synthesis, and structure-activity relationships of a series of macrocyclic MMP inhibitors

N-(Acyloxyalkyl)pyridinium Salts as Soluble Prodrugs of a Potent Platelet Activating Factor Antagonist

Aryl ketones as novel replacements for the C-terminal amide bond of succinyl hydroxamate MMP inhibitors

Pharmacology of ABT-491, a highly potent platelet-activating factor receptor antagonist

Biaryl Ether Retrohydroxamates as Potent, Long-lived, Orally Bioavailable MMP Inhibitors

Properties of ABT-299, a prodrug of A-85783, a highly potent platelet activating factor receptor antagonist

ABT-491, a highly potent and selective PAF antagonist, inhibits nasal vascular permeability associated with experimental allergic rhinitis in brown Norway rats

Gene expression profiling of multiple histone deacetylase (HDAC) inhibitors: defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines

Small atrial natriuretic peptide analogs: design, synthesis, and structural requirements for guanylate cyclase activation

Atrial peptides induce mast cell histamine release

Characterization of Matrix Metalloproteinase Inhibitors: Angiogenesis and Tumor Models

Characterization of Matrix Metalloproteinase Inhibitors: Enzymatic Assays

The role of platelet-activating factor (PAF) and the efficacy of ABT-491, a highly potent and selective PAF antagonist, in experimental allergic rhinitis

Thienopyrimidine Ureas as Novel and Potent Multitargeted Receptor Tyrosine Kinase Inhibitors

Di-tert-butyl N-acylimidodicarbonates as isolable acylating agents: mild conversion of primary carboxamides to substituted amides

1,4-Dihydroindeno[1,2-c]pyrazoles with Acetylenic Side Chains as Novel and Potent Multitargeted Receptor Tyrosine Kinase Inhibitors with Low Affinity for the hERG Ion Channel

Broad spectrum matrix metalloproteinase inhibitors : An examination of succinamide hydroxamate inhibitors with p1 Cα gem-disubstitution

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