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Viral Vectors: The Road to Reducing Genotoxicity

Toxicological sciences, 2017-02, Vol.155 (2), p.315-325

2017

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Mechanistic evidence that benzo[a]pyrene promotes an inflammatory microenvironment that drives the metastatic potential of human mammary cells

Archives of toxicology, 2018-10, Vol.92 (10), p.3223-3239

2018

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Dose-dependent synergistic and antagonistic mutation responses of binary mixtures of the environmental carcinogen benzo[a]pyrene with food-derived carcinogens

Archives of toxicology, 2018-12, Vol.92 (12), p.3459-3469

2018

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Interleukin-6 selectively induces drug metabolism to potentiate the genotoxicity of dietary carcinogens in mammary cells

Archives of toxicology, 2019-10, Vol.93 (10), p.3005-3020

2019

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Ethanol potentiates the genotoxicity of the food-derived mammary carcinogen PhIP in human estrogen receptor-positive mammary cells: mechanistic support for lifestyle factors (cooked red meat and ethanol) associated with mammary cancer

Archives of toxicology, 2018-04, Vol.92 (4), p.1639-1655

2018

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Interference with xenobiotic metabolic activity by the commonly used vehicle solvents dimethylsulfoxide and methanol in zebrafish (Danio rerio) larvae but not Daphnia magna

Chemosphere (Oxford), 2012-08, Vol.88 (8), p.912-917

2012

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Using 3D MCF-7 mammary spheroids to assess the genotoxicity of mixtures of the food-derived carcinogens benzo[a]pyrene and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

Toxicology research (Cambridge), 2016-01, Vol.5 (1), p.312-317

2016

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Transcriptional responses in neonate and adult Daphnia magna in relation to relative susceptibility to genotoxicants

Aquatic toxicology, 2011-08, Vol.104 (3), p.192-204

2011

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The mutagenic effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine in Muta™Mouse colon is attenuated by resveratrol

Toxicology research (Cambridge), 2014-01, Vol.3 (3), p.197-204

2014

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Induction of dna strand breaks by genotoxicants in the alga Chlamydomonas reinhardtii

Environmental toxicology and chemistry, 2009-09, Vol.28 (9), p.1893-1900

2009

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Genetic polymorphisms and the development of cutaneous malignant melanoma: Association of the 609 C/T NAD(P)H: quinone oxidoreductase (NQO1) polymorphism

Toxicology (Amsterdam), 2008, Vol.253 (1), p.18-18

2008

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Abstract 5454: Genotoxic consequences of exposure to mixtures of food-derived chemical carcinogens

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.5454-5454

2012

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Abstract 4630: Cruciferous vegetable glucosinolate hydrolysis products protect against Benzo[a]pyrene-induced genotoxicity

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.4630-4630

2011

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Impact of exercise-induced hypohydration on gastrointestinal integrity, function, symptoms, and systemic endotoxin and inflammatory profile

Journal of applied physiology (1985), 2019-05, Vol.126 (5), p.1281-1291

2019

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New insecticide screening platforms indicate that Mitochondrial Complex I inhibitors are susceptible to cross-resistance by mosquito P450s that metabolise pyrethroids

Scientific reports, 2020-10, Vol.10 (1), p.16232, Article 16232

2020

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How the Behavior Change Content of a Nationally Implemented Digital Diabetes Prevention Program Is Understood and Used by Participants: Qualitative Study of Fidelity of Receipt and Enactment

Journal of medical Internet research, 2023-01, Vol.25 (1), p.e41214-e41214

2023

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Farmed Mussels: A Nutritive Protein Source, Rich in Omega-3 Fatty Acids, with a Low Environmental Footprint

Nutrients, 2021-03, Vol.13 (4), p.1124

2021

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The theoretical basis of a nationally implemented type 2 diabetes prevention programme: how is the programme expected to produce changes in behaviour?

The international journal of behavioral nutrition and physical activity, 2021-05, Vol.18 (1), p.64-12, Article 64

2021

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Fidelity to Program Specification of the National Health Service Digital Diabetes Prevention Program Behavior Change Technique Content and Underpinning Theory: Document Analysis

Journal of medical Internet research, 2022-04, Vol.24 (4), p.e34253-e34253

2022

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Phase I clinical trial repurposing all-trans retinoic acid as a stromal targeting agent for pancreatic cancer

Nature communications, 2020-09, Vol.11 (1), p.4841-9, Article 4841

2020

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Description of the nationally implemented National Health Service digital diabetes prevention programme and rationale for its development: mixed methods study

BMC health services research, 2023-04, Vol.23 (1), p.373-18, Article 373

2023

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Towards in vitro models for reducing or replacing the use of animals in drug testing

Nature biomedical engineering, 2024-08, Vol.8 (8), p.930-935

2024

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CCR8 Expression Defines Tissue-Resident Memory T Cells in Human Skin

The Journal of immunology (1950), 2018-03, Vol.200 (5), p.1639-1650

2018

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Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise

Cell metabolism, 2018-01, Vol.27 (1), p.237-251.e4

2018

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Viral Vectors: The Road to Reducing Genotoxicity

Mechanistic evidence that benzo[a]pyrene promotes an inflammatory microenvironment that drives the metastatic potential of human mammary cells

Dose-dependent synergistic and antagonistic mutation responses of binary mixtures of the environmental carcinogen benzo[a]pyrene with food-derived carcinogens

Interleukin-6 selectively induces drug metabolism to potentiate the genotoxicity of dietary carcinogens in mammary cells

Ethanol potentiates the genotoxicity of the food-derived mammary carcinogen PhIP in human estrogen receptor-positive mammary cells: mechanistic support for lifestyle factors (cooked red meat and ethanol) associated with mammary cancer

Interference with xenobiotic metabolic activity by the commonly used vehicle solvents dimethylsulfoxide and methanol in zebrafish (Danio rerio) larvae but not Daphnia magna

Using 3D MCF-7 mammary spheroids to assess the genotoxicity of mixtures of the food-derived carcinogens benzo[a]pyrene and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

Transcriptional responses in neonate and adult Daphnia magna in relation to relative susceptibility to genotoxicants

The mutagenic effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine in Muta™Mouse colon is attenuated by resveratrol

Induction of dna strand breaks by genotoxicants in the alga Chlamydomonas reinhardtii

Genetic polymorphisms and the development of cutaneous malignant melanoma: Association of the 609 C/T NAD(P)H: quinone oxidoreductase (NQO1) polymorphism

Abstract 5454: Genotoxic consequences of exposure to mixtures of food-derived chemical carcinogens

Abstract 4630: Cruciferous vegetable glucosinolate hydrolysis products protect against Benzo[a]pyrene-induced genotoxicity

Impact of exercise-induced hypohydration on gastrointestinal integrity, function, symptoms, and systemic endotoxin and inflammatory profile

New insecticide screening platforms indicate that Mitochondrial Complex I inhibitors are susceptible to cross-resistance by mosquito P450s that metabolise pyrethroids

How the Behavior Change Content of a Nationally Implemented Digital Diabetes Prevention Program Is Understood and Used by Participants: Qualitative Study of Fidelity of Receipt and Enactment

Farmed Mussels: A Nutritive Protein Source, Rich in Omega-3 Fatty Acids, with a Low Environmental Footprint

The theoretical basis of a nationally implemented type 2 diabetes prevention programme: how is the programme expected to produce changes in behaviour?

Fidelity to Program Specification of the National Health Service Digital Diabetes Prevention Program Behavior Change Technique Content and Underpinning Theory: Document Analysis

Two subsets of stem-like CD8 + memory T cell progenitors with distinct fate commitments in humans

Phase I clinical trial repurposing all-trans retinoic acid as a stromal targeting agent for pancreatic cancer

Description of the nationally implemented National Health Service digital diabetes prevention programme and rationale for its development: mixed methods study

Towards in vitro models for reducing or replacing the use of animals in drug testing

CCR8 Expression Defines Tissue-Resident Memory T Cells in Human Skin

Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise

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