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GLYX-13, a NMDA Receptor Glycine-Site Functional Partial Agonist, Induces Antidepressant-Like Effects Without Ketamine-Like Side Effects

Neuropsychopharmacology (New York, N.Y.), 2013-04, Vol.38 (5), p.729-742

2013

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GLYX-13, an NMDA receptor glycine site functional partial agonist enhances cognition and produces antidepressant effects without the psychotomimetic side effects of NMDA receptor antagonists

Expert opinion on investigational drugs, 2014-02, Vol.23 (2), p.243-254

2014

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Behavioral Effects of a Novel Benzofuranyl-Piperazine Serotonin-2C Receptor Agonist Suggest a Potential Therapeutic Application in the Treatment of Obsessive-Compulsive Disorder

Frontiers in psychiatry, 2017-05, Vol.8, p.89-89

2017

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Comparison of the effects of antipsychotics on a delayed radial maze task in the rat

Psychopharmacologia, 2003-08, Vol.168 (4), p.410-416

2003

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SR141716A, a cannabinoid CB1 receptor antagonist, improves memory in a delayed radial maze task

European journal of pharmacology, 2003-09, Vol.477 (3), p.213-217

2003

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GLYX-13, a NMDA Receptor Glycine-Site Functional Partial Agonist, Induces Antidepressant-Like Effects Without ketamine-like Side Effects

Neuropsychopharmacology (New York, N.Y.), 2013-06, Vol.38 (7), p.1374-1374

2013

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Correction: GLYX-13, a NMDA Receptor Glycine-Site Functional Partial Agonist, Induces Antidepressant-Like Effects Without ketamine-like Side Effects

Neuropsychopharmacology (New York, N.Y.), 2013-06, Vol.38 (7), p.1374-1374

2013

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Selective Serotonin Reuptake Inhibitors Decrease Impulsive Behavior as Measured by an Adjusting Delay Procedure in the Pigeon

Neuropsychopharmacology (New York, N.Y.), 2002-09, Vol.27 (3), p.421-429

2002

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The absolute configurations and pharmacological activities of the optical isomers of fluoxetine, a selective serotonin-uptake inhibitor

Journal of medicinal chemistry, 1988-07, Vol.31 (7), p.1412-1417

1988

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Selective opioid receptor agonists and antagonists: research tools and potential therapeutic agents

Journal of medicinal chemistry, 1990-03, Vol.33 (3), p.895-902

1990

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Behavioral pharmacology of olanzapine: a novel antipsychotic drug

The journal of clinical psychiatry, 1997, Vol.58 Suppl 10, p.37

1997

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The effect of streptozotocin-induced diabetes on cell proliferation in the rat dentate gyrus

Neuroscience letters, 2000-10, Vol.293 (2), p.91-94

2000

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Structure−Activity Studies of 6-(Tetrazolylalkyl)-Substituted Decahydroisoquinoline-3-carboxylic Acid AMPA Receptor Antagonists. 1. Effects of Stereochemistry, Chain Length, and Chain Substitution

Journal of medicinal chemistry, 1996-05, Vol.39 (11), p.2219-2231

1996

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Synthesis and analgesic properties of N-substituted trans-4a-aryldecahydroisoquinolines

Journal of medicinal chemistry, 1988-03, Vol.31 (3), p.555-560

1988

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Anticonvulsant Properties of N‐Substituted α,α‐Diamino Acid Derivatives

Journal of pharmaceutical sciences, 1994-05, Vol.83 (5), p.689-691

1994

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Increased food consumption by clozapine, but not by olanzapine, in satiated rats

Drug development research, 1997-05, Vol.41 (1), p.48-50

1997

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The behavioral pharmacology of NMDA receptor antagonists

Trends in pharmacological sciences (Regular ed.), 1990-10, Vol.11 (10), p.423-428

1990

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The novel 5-Hydroxytryptamine(1A) antagonist LY426965: effects on nicotine withdrawal and interactions with fluoxetine

The Journal of pharmacology and experimental therapeutics, 2000-08, Vol.294 (2), p.688

2000

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Fluoxetine, a Selective Serotonin‐Uptake Inhibitor, Enhances the Anticonvulsant Effects of Phenytoin, Carbamazepine, and Ameltolide (LY 201116)

Epilepsia (Copenhagen), 1992-05, Vol.33 (3), p.573-576

Leander, J. David

1992

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k-Opioid diuretic effects of tifluadom, a benzodiazepine opioid agonist

Journal of pharmacy and pharmacology, 1984-08, Vol.36 (8), p.555-556

Leander, J. David

1984

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(3SR,4aRS,6RS,8aRS)-6-[2-(1H-Tetrazol-5-yl)ethyl]decahydroisoquinoline-3-carboxylic acid: a structurally novel, systemically active, competitive AMPA receptor antagonist

Journal of medicinal chemistry, 1993-07, Vol.36 (14), p.2046-2048

1993

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Discovery of a Potent, Peripherally Selective trans-3,4-Dimethyl-4-(3-hydroxyphenyl)piperidine Opioid Antagonist for the Treatment of Gastrointestinal Motility Disorders

Journal of medicinal chemistry, 1994-07, Vol.37 (15), p.2262-2265

1994

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Pharmacological Effects of Enantiomers of 4‐Amino‐N‐(α‐methylbenzyl)Benzamide, a Chemically Novel Anticonvulsant

Epilepsia (Copenhagen), 1988-01, Vol.29 (1), p.83-90

1988

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Synthesis and anticonvulsant activity of 3-aryl-5H-2,3-benzodiazepine AMPA antagonists

Bioorganic & medicinal chemistry letters, 1999-07, Vol.9 (14), p.1953-1956

1999

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Buprenorphine is a potent κ-opioid receptor antagonist in pigeons and mice

European journal of pharmacology, 1988-07, Vol.151 (3), p.457-461

Leander, J.David

1988

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GLYX-13, a NMDA Receptor Glycine-Site Functional Partial Agonist, Induces Antidepressant-Like Effects Without Ketamine-Like Side Effects

GLYX-13, an NMDA receptor glycine site functional partial agonist enhances cognition and produces antidepressant effects without the psychotomimetic side effects of NMDA receptor antagonists

Behavioral Effects of a Novel Benzofuranyl-Piperazine Serotonin-2C Receptor Agonist Suggest a Potential Therapeutic Application in the Treatment of Obsessive-Compulsive Disorder

Comparison of the effects of antipsychotics on a delayed radial maze task in the rat

SR141716A, a cannabinoid CB1 receptor antagonist, improves memory in a delayed radial maze task

GLYX-13, a NMDA Receptor Glycine-Site Functional Partial Agonist, Induces Antidepressant-Like Effects Without ketamine-like Side Effects

Correction: GLYX-13, a NMDA Receptor Glycine-Site Functional Partial Agonist, Induces Antidepressant-Like Effects Without ketamine-like Side Effects

Selective Serotonin Reuptake Inhibitors Decrease Impulsive Behavior as Measured by an Adjusting Delay Procedure in the Pigeon

The absolute configurations and pharmacological activities of the optical isomers of fluoxetine, a selective serotonin-uptake inhibitor

Selective opioid receptor agonists and antagonists: research tools and potential therapeutic agents

Behavioral pharmacology of olanzapine: a novel antipsychotic drug

The effect of streptozotocin-induced diabetes on cell proliferation in the rat dentate gyrus

Structure−Activity Studies of 6-(Tetrazolylalkyl)-Substituted Decahydroisoquinoline-3-carboxylic Acid AMPA Receptor Antagonists. 1. Effects of Stereochemistry, Chain Length, and Chain Substitution

Synthesis and analgesic properties of N-substituted trans-4a-aryldecahydroisoquinolines

Anticonvulsant Properties of N‐Substituted α,α‐Diamino Acid Derivatives

Increased food consumption by clozapine, but not by olanzapine, in satiated rats

The behavioral pharmacology of NMDA receptor antagonists

The novel 5-Hydroxytryptamine(1A) antagonist LY426965: effects on nicotine withdrawal and interactions with fluoxetine

Fluoxetine, a Selective Serotonin‐Uptake Inhibitor, Enhances the Anticonvulsant Effects of Phenytoin, Carbamazepine, and Ameltolide (LY 201116)

k-Opioid diuretic effects of tifluadom, a benzodiazepine opioid agonist

(3SR,4aRS,6RS,8aRS)-6-[2-(1H-Tetrazol-5-yl)ethyl]decahydroisoquinoline-3-carboxylic acid: a structurally novel, systemically active, competitive AMPA receptor antagonist

Discovery of a Potent, Peripherally Selective trans-3,4-Dimethyl-4-(3-hydroxyphenyl)piperidine Opioid Antagonist for the Treatment of Gastrointestinal Motility Disorders

Pharmacological Effects of Enantiomers of 4‐Amino‐N‐(α‐methylbenzyl)Benzamide, a Chemically Novel Anticonvulsant

Synthesis and anticonvulsant activity of 3-aryl-5H-2,3-benzodiazepine AMPA antagonists

Buprenorphine is a potent κ-opioid receptor antagonist in pigeons and mice

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