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Epithelial-mesenchymal transition and inflammation at the site of the primary tumor

Seminars in cancer biology, 2017-12, Vol.47, p.177-184

2017

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Dishonorable Discharge: The Oncogenic Roles of Cleaved E-Cadherin Fragments

Cancer research (Chicago, Ill.), 2012-06, Vol.72 (12), p.2917-2923

2012

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A novel bifunctional anti-PD-L1/TGF-β Trap fusion protein (M7824) efficiently reverts mesenchymalization of human lung cancer cells

Oncoimmunology, 2017-10, Vol.6 (10), p.e1349589-e1349589

2017

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Neutralization of IL-8 decreases tumor PMN-MDSCs and reduces mesenchymalization of claudin-low triple-negative breast cancer

JCI insight, 2017-11, Vol.2 (21)

2017

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Brachyury-YAP Regulatory Axis Drives Stemness and Growth in Cancer

Cell reports (Cambridge), 2017-10, Vol.21 (2), p.495-507

2017

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Wilms' tumor protein induces an epithelial-mesenchymal hybrid differentiation state in clear cell renal cell carcinoma

PloS one, 2014-07, Vol.9 (7), p.e102041-e102041

2014

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Comprehensive immunophenotyping of solid tumor-infiltrating immune cells reveals the expression characteristics of LAG-3 and its ligands

Frontiers in immunology, 2023-09, Vol.14, p.1151748-1151748

2023

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Preclinical Characterization of a Novel Monoclonal Antibody NEO-201 for the Treatment of Human Carcinomas

Frontiers in immunology, 2018-01, Vol.8, p.1899-1899

2018

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Evaluation of the Anti-Tumor Activity of the Humanized Monoclonal Antibody NEO-201 in Preclinical Models of Ovarian Cancer

Frontiers in oncology, 2020-06, Vol.10, p.805-805

2020

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Gramicidin A: A New Mission for an Old Antibiotic

Journal of kidney cancer and VHL, 2015-01, Vol.2 (1), p.15-24

2015

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Gramicidin A induces metabolic dysfunction and energy depletion leading to cell death in renal cell carcinoma cells

Molecular cancer therapeutics, 2013-11, Vol.12 (11), p.2296-2307

2013

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The IL-8/IL-8R Axis: A Double Agent in Tumor Immune Resistance

Vaccines (Basel), 2016-06, Vol.4 (3), p.22

2016

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Gramicidin A blocks tumor growth and angiogenesis through inhibition of hypoxia-inducible factor in renal cell carcinoma

Molecular cancer therapeutics, 2014-04, Vol.13 (4), p.788-799

2014

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Pharmacological and immunological targeting of tumor mesenchymalization

Pharmacology & therapeutics (Oxford), 2017-02, Vol.170, p.212-225

2017

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MUC1 upregulation promotes immune resistance in tumor cells undergoing brachyury-mediated epithelial-mesenchymal transition

Oncoimmunology, 2016-04, Vol.5 (4), p.e1117738-e1117738

2016

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Targeting Estrogen Receptor Signaling with Fulvestrant Enhances Immune and Chemotherapy-Mediated Cytotoxicity of Human Lung Cancer

Clinical cancer research, 2016-12, Vol.22 (24), p.6204-6216

2016

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IL-8 signaling is involved in resistance of lung carcinoma cells to erlotinib

Oncotarget, 2016-07, Vol.7 (27), p.42031-42044

2016

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Development of Cancer Vaccines Targeting Brachyury, a Transcription Factor Associated with Tumor Epithelial-Mesenchymal Transition

Cells, tissues, organs, 2017-01, Vol.203 (2), p.128-138

2017

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An IL-15 Superagonist, ALT-803, Enhances Antibody-Dependent Cell-Mediated Cytotoxicity Elicited by the Monoclonal Antibody NEO-201 Against Human Carcinoma Cells

Cancer biotherapy & radiopharmaceuticals, 2019-04, Vol.34 (3), p.147-159

2019

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The Monoclonal Antibody NEO-201 Enhances Natural Killer Cell Cytotoxicity Against Tumor Cells Through Blockade of the Inhibitory CEACAM5/CEACAM1 Immune Checkpoint Pathway

Cancer biotherapy & radiopharmaceuticals, 2020-04, Vol.35 (3), p.190-198

2020

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Identification and characterization of enhancer agonist human cytotoxic T-cell epitopes of the human papillomavirus type 16 (HPV16) E6/E7

Vaccine, 2017-05, Vol.35 (19), p.2605-2611

2017

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Epigenetic silencing of Na,K-ATPase β1 subunit gene ATP1B1 by methylation in clear cell renal cell carcinoma

Epigenetics, 2014-01, Vol.9 (4), p.579-586

2014

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The generation and analyses of a novel combination of recombinant adenovirus vaccines targeting three tumor antigens as an immunotherapeutic

Oncotarget, 2015-10, Vol.6 (31), p.31344-31359

2015

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Abstract 611: Reversion of mesenchymal features in NSCLC cells using M7824, a first-in-class bi-functional immunotherapeutic agent targeting PD-L1 and TGFβ1 (TGFβ TRAP)

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.611-611

2017

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Abstract 3821: The neoantigen-targeting antibody NEO-201 enhances NK cell-dependent killing of tumor cells through blockade of the inhibitory CEACAM5/CEACAM1 immune checkpoint pathway

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.3821-3821

2018

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Epithelial-mesenchymal transition and inflammation at the site of the primary tumor

Dishonorable Discharge: The Oncogenic Roles of Cleaved E-Cadherin Fragments

A novel bifunctional anti-PD-L1/TGF-β Trap fusion protein (M7824) efficiently reverts mesenchymalization of human lung cancer cells

Neutralization of IL-8 decreases tumor PMN-MDSCs and reduces mesenchymalization of claudin-low triple-negative breast cancer

Brachyury-YAP Regulatory Axis Drives Stemness and Growth in Cancer

Wilms' tumor protein induces an epithelial-mesenchymal hybrid differentiation state in clear cell renal cell carcinoma

Comprehensive immunophenotyping of solid tumor-infiltrating immune cells reveals the expression characteristics of LAG-3 and its ligands

Preclinical Characterization of a Novel Monoclonal Antibody NEO-201 for the Treatment of Human Carcinomas

Evaluation of the Anti-Tumor Activity of the Humanized Monoclonal Antibody NEO-201 in Preclinical Models of Ovarian Cancer

Gramicidin A: A New Mission for an Old Antibiotic

Gramicidin A induces metabolic dysfunction and energy depletion leading to cell death in renal cell carcinoma cells

The IL-8/IL-8R Axis: A Double Agent in Tumor Immune Resistance

Gramicidin A blocks tumor growth and angiogenesis through inhibition of hypoxia-inducible factor in renal cell carcinoma

Pharmacological and immunological targeting of tumor mesenchymalization

MUC1 upregulation promotes immune resistance in tumor cells undergoing brachyury-mediated epithelial-mesenchymal transition

Targeting Estrogen Receptor Signaling with Fulvestrant Enhances Immune and Chemotherapy-Mediated Cytotoxicity of Human Lung Cancer

IL-8 signaling is involved in resistance of lung carcinoma cells to erlotinib

Development of Cancer Vaccines Targeting Brachyury, a Transcription Factor Associated with Tumor Epithelial-Mesenchymal Transition

An IL-15 Superagonist, ALT-803, Enhances Antibody-Dependent Cell-Mediated Cytotoxicity Elicited by the Monoclonal Antibody NEO-201 Against Human Carcinoma Cells

The Monoclonal Antibody NEO-201 Enhances Natural Killer Cell Cytotoxicity Against Tumor Cells Through Blockade of the Inhibitory CEACAM5/CEACAM1 Immune Checkpoint Pathway

Identification and characterization of enhancer agonist human cytotoxic T-cell epitopes of the human papillomavirus type 16 (HPV16) E6/E7

Epigenetic silencing of Na,K-ATPase β1 subunit gene ATP1B1 by methylation in clear cell renal cell carcinoma

The generation and analyses of a novel combination of recombinant adenovirus vaccines targeting three tumor antigens as an immunotherapeutic

Abstract 611: Reversion of mesenchymal features in NSCLC cells using M7824, a first-in-class bi-functional immunotherapeutic agent targeting PD-L1 and TGFβ1 (TGFβ TRAP)

Abstract 3821: The neoantigen-targeting antibody NEO-201 enhances NK cell-dependent killing of tumor cells through blockade of the inhibitory CEACAM5/CEACAM1 immune checkpoint pathway

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