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Targeted anti-mitotic therapies: can we improve on tubulin agents?

Nature reviews. Cancer, 2007-02, Vol.7 (2), p.107-117

2007

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A Dose-Escalation Study of Recombinant Human Interleukin-18 Using Two Different Schedules of Administration in Patients with Cancer

Clinical cancer research, 2008-06, Vol.14 (11), p.3462-3469

2008

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Clinical and Biological Effects of Recombinant Human Interleukin-18 Administered by Intravenous Infusion to Patients with Advanced Cancer

Clinical cancer research, 2006-07, Vol.12 (14), p.4265-4273

2006

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first in human study of SB-743921, a kinesin spindle protein inhibitor, to determine pharmacokinetics, biologic effects and establish a recommended phase II dose

Cancer chemotherapy and pharmacology, 2011-02, Vol.67 (2), p.447-454

2011

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Phase I Study of GSK461364, a Specific and Competitive Polo-like Kinase 1 Inhibitor, in Patients with Advanced Solid Malignancies

Clinical cancer research, 2011-05, Vol.17 (10), p.3420-3430

2011

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A Phase I/II Trial of Pazopanib in Combination with Lapatinib in Adult Patients with Relapsed Malignant Glioma

Clinical cancer research, 2013-02, Vol.19 (4), p.900-908

2013

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Effect of lapatinib on oral digoxin absorption in patients

Clinical pharmacology in drug development, 2015-11, Vol.4 (6), p.449-453

2015

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A phase 2, randomized study of SB‐485232, rhIL‐18, in patients with previously untreated metastatic melanoma

Cancer, 2009-02, Vol.115 (4), p.859-868

2009

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Phase I Dose-Finding Study of Pazopanib in Hepatocellular Carcinoma: Evaluation of Early Efficacy, Pharmacokinetics, and Pharmacodynamics

Clinical cancer research, 2011-11, Vol.17 (21), p.6914-6923

2011

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Bioavailability, metabolism and disposition of oral pazopanib in patients with advanced cancer

Xenobiotica, 2013-05, Vol.43 (5), p.443-453

2013

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A randomized, double-blind, placebo-controlled study to evaluate the effect of repeated oral doses of pazopanib on cardiac conduction in patients with solid tumors

Cancer chemotherapy and pharmacology, 2013-03, Vol.71 (3), p.565-573

2013

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Phase I study of pazopanib in combination with paclitaxel and carboplatin given every 21 days in patients with advanced solid tumors

Molecular cancer therapeutics, 2012-08, Vol.11 (8), p.1820-1828

2012

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Pharmacodynamics and pharmacokinetics of oral topotecan in patients with advanced solid tumours and impaired renal function

British journal of clinical pharmacology, 2015-08, Vol.80 (2), p.253-266

2015

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Phase I Study of Pazopanib in Combination with Weekly Paclitaxel in Patients with Advanced Solid Tumors

The oncologist (Dayton, Ohio), 2010-12, Vol.15 (12), p.1253-1261

2010

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A Phase I Study of Capecitabine, Oxaliplatin, and Lapatinib in Metastatic or Advanced Solid Tumors

Clinical colorectal cancer, 2011-03, Vol.10 (1), p.57-62

2011

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Early incidence of immune-related adverse events (irAEs) predicts efficacy in patients (pts) with solid tumors treated with immune-checkpoint inhibitors (ICIs)

Journal of clinical oncology, 2019-05, Vol.37 (15_suppl), p.2563-2563

2019

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A phase I/II first-in-human study of a novel anti-MAGE-A4 TCR/anti-CD3 bispecific (IMC-C103C) as monotherapy and in combination with atezolizumab in HLA-A02:01-positive patients with MAGE-A4-positive advanced solid tumors (IMC-C103C-101)

Journal of clinical oncology, 2020-05, Vol.38 (15_suppl), p.TPS3165-TPS3165

2020

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Evaluation of anti-cancer stem cell activity of the anti-DLL4 antibody MEDI0639 in a phase I clinical trial of SCLC

Journal of clinical oncology, 2016-05, Vol.34 (15_suppl), p.e20093-e20093

2016

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Vaccination strategies for lymphomas

Current oncology reports, 2003-09, Vol.5 (5), p.380-386

2003

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Phase 1 study of MEDI4736, an anti-PD-L1 antibody, in combination with dabrafenib and trametinib or trametinib alone in patients with unresectable or metastatic melanoma

Journal of clinical oncology, 2014-05, Vol.32 (15_suppl), p.TPS9108-TPS9108

2014

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Effect of Irradiation on Cytokine Production, MHC Antigen Expression, and Vaccine Potential of Interleukin-2 and Interferon-γ Gene-Modified Melanoma Cells

Cellular immunology, 1996-08, Vol.171 (2), p.246-254

1996

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Immunological memory induced by genetically transduced tumor cells

Annals of surgical oncology, 1996-05, Vol.3 (3), p.247-254

1996

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Perovskite solar cells with CuSCN hole extraction layers yield stabilized efficiencies greater than 20

Science (American Association for the Advancement of Science), 2017-11, Vol.358 (6364), p.768-771

2017

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Exploring the evidence base for national and regional policy interventions to combat resistance

The Lancet (British edition), 2016-01, Vol.387 (10015), p.285-295

2016

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The Role of Rubidium in Multiple‐Cation‐Based High‐Efficiency Perovskite Solar Cells

Advanced materials (Weinheim), 2017-10, Vol.29 (40), p.n/a

2017

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Targeted anti-mitotic therapies: can we improve on tubulin agents?

A Dose-Escalation Study of Recombinant Human Interleukin-18 Using Two Different Schedules of Administration in Patients with Cancer

Clinical and Biological Effects of Recombinant Human Interleukin-18 Administered by Intravenous Infusion to Patients with Advanced Cancer

first in human study of SB-743921, a kinesin spindle protein inhibitor, to determine pharmacokinetics, biologic effects and establish a recommended phase II dose

Phase I Study of GSK461364, a Specific and Competitive Polo-like Kinase 1 Inhibitor, in Patients with Advanced Solid Malignancies

A Phase I/II Trial of Pazopanib in Combination with Lapatinib in Adult Patients with Relapsed Malignant Glioma

Effect of lapatinib on oral digoxin absorption in patients

A phase 2, randomized study of SB‐485232, rhIL‐18, in patients with previously untreated metastatic melanoma

Phase I Dose-Finding Study of Pazopanib in Hepatocellular Carcinoma: Evaluation of Early Efficacy, Pharmacokinetics, and Pharmacodynamics

Bioavailability, metabolism and disposition of oral pazopanib in patients with advanced cancer

A randomized, double-blind, placebo-controlled study to evaluate the effect of repeated oral doses of pazopanib on cardiac conduction in patients with solid tumors

Phase I study of pazopanib in combination with paclitaxel and carboplatin given every 21 days in patients with advanced solid tumors

Pharmacodynamics and pharmacokinetics of oral topotecan in patients with advanced solid tumours and impaired renal function

Phase I Study of Pazopanib in Combination with Weekly Paclitaxel in Patients with Advanced Solid Tumors

A Phase I Study of Capecitabine, Oxaliplatin, and Lapatinib in Metastatic or Advanced Solid Tumors

Early incidence of immune-related adverse events (irAEs) predicts efficacy in patients (pts) with solid tumors treated with immune-checkpoint inhibitors (ICIs)

A phase I/II first-in-human study of a novel anti-MAGE-A4 TCR/anti-CD3 bispecific (IMC-C103C) as monotherapy and in combination with atezolizumab in HLA-A02:01-positive patients with MAGE-A4-positive advanced solid tumors (IMC-C103C-101)

Evaluation of anti-cancer stem cell activity of the anti-DLL4 antibody MEDI0639 in a phase I clinical trial of SCLC

Vaccination strategies for lymphomas

Phase 1 study of MEDI4736, an anti-PD-L1 antibody, in combination with dabrafenib and trametinib or trametinib alone in patients with unresectable or metastatic melanoma

Effect of Irradiation on Cytokine Production, MHC Antigen Expression, and Vaccine Potential of Interleukin-2 and Interferon-γ Gene-Modified Melanoma Cells

Immunological memory induced by genetically transduced tumor cells

Perovskite solar cells with CuSCN hole extraction layers yield stabilized efficiencies greater than 20

Exploring the evidence base for national and regional policy interventions to combat resistance

The Role of Rubidium in Multiple‐Cation‐Based High‐Efficiency Perovskite Solar Cells

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