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Structural approaches to explain the selectivity of COX-2 inhibitors: is there a common pharmacophore?

Current medicinal chemistry, 2000-11, Vol.7 (11), p.1101

2000

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Novel insights and therapeutical applications in the field of inhibitors of COX-2

Current medicinal chemistry, 2004-12, Vol.11 (24), p.3147

2004

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Antagonists and agonists at the glycine site of the NMDA receptor for therapeutic interventions

European Journal of Medicinal Chemistry, 2003-07, Vol.38 (7), p.661-670

2003

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The NMDA receptor complex: a promising target for novel antiepileptic strategies

Current medicinal chemistry, 2001-09, Vol.8 (11), p.1275

2001

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Cyclooxygenase inhibitors – current status and future prospects

European Journal of Medicinal Chemistry, 2001-02, Vol.36 (2), p.109-126

2001

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1235 POSTER Moguntinones – New Selective Inhibitors for Treating Human Gastrointestinal Tumours

European journal of cancer (1990), 2011, Vol.47, p.S155-S155

2011

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A Novel Quantitative Chick Embryo Assay as an Angiogenesis Model Using Digital Image Analysis

Anticancer research, 2004-05, Vol.24 (3A), p.1545-1551

2004

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Synthesis, labelling and evaluation of hydantoin-substituted indole carboxylic acids as potential ligands for positron emission tomography imaging of the glycine binding site of the N-methyl-d-aspartate receptor

Journal of labelled compounds & radiopharmaceuticals, 2011-08, Vol.54 (10), p.645-656

2011

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Licofelone, a novel 5-LOX/COX-inhibitor, attenuates leukocyte rolling and adhesion on endothelium under flow

Biochemical pharmacology, 2005-07, Vol.70 (1), p.30-36

2005

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In-vitro test system for the evaluation of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) inhibitors based on a single HPLC run with UV detection using bovine aortic coronary endothelial cells (BAECs)

Inflammation research, 2001-05, Vol.50 (5), p.262-269

2001

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Design, Synthesis, and Biological Evaluation of 3,4-Diarylmaleimides as Angiogenesis Inhibitors

Journal of medicinal chemistry, 2006-02, Vol.49 (4), p.1271-1281

2006

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The pyrrole moiety as a template for COX-1/COX-2 inhibitors

European journal of medicinal chemistry, 2000-05, Vol.35 (5), p.499-510

2000

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Cyclooxygenase-1/2 (COX-1/COX-2) and 5-lipoxygenase (5-LOX) inhibitors of the 6,7-diaryl-2,3-1H-dihydropyrrolizine type

European journal of medicinal chemistry, 2002-12, Vol.37 (12), p.953-959

2002

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Diaryl-dithiolanes and -isothiazoles: COX-1/COX-2 and 5-LOX-inhibitory, OH scavenging and anti-adhesive activities

Bioorganic & medicinal chemistry, 2009-01, Vol.17 (2), p.558-568

2009

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2-Aryl-pyrrolo[2,1-b]benzothiazole als selektive oder duale Inhibitoren der Cyclooxygenase und 5-Lipoxygenase. 21. Mitt.: Nichtsteroidale Antiphlogistika

Pharmazie, 1997-06, Vol.52 (6), p.428-436

1997

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Benzimidazoles as NMDA Glycine-Site Antagonists: Study on the Structural Requirements in 2-Position of the Ligand

Archiv der Pharmazie (Weinheim), 2000-05, Vol.333 (5), p.123-129

2000

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A Novel Class of Potent Nonglycosidic and Nonpeptidic Pan-Selectin Inhibitors

Journal of medicinal chemistry, 2006-10, Vol.49 (20), p.5988-5999

2006

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Hydantoin-Substituted 4,6-Dichloroindole-2-carboxylic Acids as Ligands with High Affinity for the Glycine Binding Site of the NMDA Receptor

Journal of medicinal chemistry, 2003-01, Vol.46 (1), p.64-73

2003

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Inhibitory Activity of Tryptanthrin on Prostaglandin and Leukotriene Synthesis

Planta medica, 2002-10, Vol.68 (10), p.875-880

2002

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Variations of acidic functions at position 2 and substituents at positions 4, 5 and 6 of the indole moiety and their effect on NMDA-glycine site affinity

European journal of medicinal chemistry, 2003-10, Vol.38 (10), p.855-865

2003

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A Novel Series of 2-Carboxytetrahydroquinolines Provides New Insights into the Eastern Region of Glycine Site NMDA Antagonists

Archiv der Pharmazie (Weinheim), 2000-08, Vol.333 (8), p.267-274

2000

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1-imidazolyl(alkyl)-substituted di- and tetrahydroquinolines and analogues: syntheses and evaluation of dual inhibitors of thromboxane A(2) synthase and aromatase

Journal of medicinal chemistry, 2000-05, Vol.43 (9), p.1841-1851

2000

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Regioisomeric 3-, 4- and 5-aminomethyl isoxazoles: synthesis and muscarinic activity

European journal of medicinal chemistry, 1995, Vol.30 (11), p.839-850

1995

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COX-1/COX-2 inhibitors based on the methanone moiety

European journal of medicinal chemistry, 2002-02, Vol.37 (2), p.147-161

2002

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Structure−Activity Relationships of Dimethindene Derivatives as New M 2 -Selective Muscarinic Receptor Antagonists

Journal of medicinal chemistry, 2003-02, Vol.46 (5), p.856-867

2003

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Structural approaches to explain the selectivity of COX-2 inhibitors: is there a common pharmacophore?

Novel insights and therapeutical applications in the field of inhibitors of COX-2

Antagonists and agonists at the glycine site of the NMDA receptor for therapeutic interventions

The NMDA receptor complex: a promising target for novel antiepileptic strategies

Cyclooxygenase inhibitors – current status and future prospects

1235 POSTER Moguntinones – New Selective Inhibitors for Treating Human Gastrointestinal Tumours

A Novel Quantitative Chick Embryo Assay as an Angiogenesis Model Using Digital Image Analysis

Synthesis, labelling and evaluation of hydantoin-substituted indole carboxylic acids as potential ligands for positron emission tomography imaging of the glycine binding site of the N-methyl-d-aspartate receptor

Licofelone, a novel 5-LOX/COX-inhibitor, attenuates leukocyte rolling and adhesion on endothelium under flow

In-vitro test system for the evaluation of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) inhibitors based on a single HPLC run with UV detection using bovine aortic coronary endothelial cells (BAECs)

Design, Synthesis, and Biological Evaluation of 3,4-Diarylmaleimides as Angiogenesis Inhibitors

The pyrrole moiety as a template for COX-1/COX-2 inhibitors

Cyclooxygenase-1/2 (COX-1/COX-2) and 5-lipoxygenase (5-LOX) inhibitors of the 6,7-diaryl-2,3-1H-dihydropyrrolizine type

Diaryl-dithiolanes and -isothiazoles: COX-1/COX-2 and 5-LOX-inhibitory, OH scavenging and anti-adhesive activities

2-Aryl-pyrrolo[2,1-b]benzothiazole als selektive oder duale Inhibitoren der Cyclooxygenase und 5-Lipoxygenase. 21. Mitt.: Nichtsteroidale Antiphlogistika

Benzimidazoles as NMDA Glycine-Site Antagonists: Study on the Structural Requirements in 2-Position of the Ligand

A Novel Class of Potent Nonglycosidic and Nonpeptidic Pan-Selectin Inhibitors

Hydantoin-Substituted 4,6-Dichloroindole-2-carboxylic Acids as Ligands with High Affinity for the Glycine Binding Site of the NMDA Receptor

Inhibitory Activity of Tryptanthrin on Prostaglandin and Leukotriene Synthesis

Variations of acidic functions at position 2 and substituents at positions 4, 5 and 6 of the indole moiety and their effect on NMDA-glycine site affinity

A Novel Series of 2-Carboxytetrahydroquinolines Provides New Insights into the Eastern Region of Glycine Site NMDA Antagonists

1-imidazolyl(alkyl)-substituted di- and tetrahydroquinolines and analogues: syntheses and evaluation of dual inhibitors of thromboxane A(2) synthase and aromatase

Regioisomeric 3-, 4- and 5-aminomethyl isoxazoles: synthesis and muscarinic activity

COX-1/COX-2 inhibitors based on the methanone moiety

Structure−Activity Relationships of Dimethindene Derivatives as New M 2 -Selective Muscarinic Receptor Antagonists

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