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Standing the test of time: targeting thymidylate biosynthesis in cancer therapy

Nature reviews. Clinical oncology, 2014-05, Vol.11 (5), p.282-298

2014

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ERCC1 and Thymidylate Synthase mRNA Levels Predict Survival for Colorectal Cancer Patients Receiving Combination Oxaliplatin and Fluorouracil Chemotherapy

Journal of clinical oncology, 2001-12, Vol.19 (23), p.4298-4304

2001

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MDR1 and ERCC1 Expression Predict Outcome of Patients with Locally Advanced Bladder Cancer Receiving Adjuvant Chemotherapy

Neoplasia (New York, N.Y.), 2010-08, Vol.12 (8), p.628-636

2010

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An In vivo Platform for Translational Drug Development in Pancreatic Cancer

Clinical cancer research, 2006-08, Vol.12 (15), p.4652-4661

2006

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Folates as adjuvants to anticancer agents: chemical rationale and mechanism of action

Critical reviews in oncology/hematology, 2016-10, Vol.106, p.118-131

2016

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Epidermal Growth Factor Receptor and HER2-neu mRNA Expression in Non-Small Cell Lung Cancer Is Correlated with Survival

Clinical cancer research, 2001-07, Vol.7 (7), p.1850-1855

2001

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High Expression of HIF1a Is a Predictor of Clinical Outcome in Patients with Pancreatic Ductal Adenocarcinomas and Correlated to PDGFA, VEGF, and bFGF

Neoplasia (New York, N.Y.), 2008-07, Vol.10 (7), p.674-679

2008

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High Gene Expression of TS1, GSTP1, and ERCC1 Are Risk Factors for Survival in Patients Treated with Trimodality Therapy for Esophageal Cancer

Clinical cancer research, 2005-03, Vol.11 (6), p.2215-2221

2005

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Different Lengths of a Polymorphic Repeat Sequence in the Thymidylate Synthase Gene Affect Translational Efficiency but Not Its Gene Expression

Clinical cancer research, 2001-12, Vol.7 (12), p.4096-4101

2001

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Thymidylate synthase, dihydropyrimidine dehydrogenase, ERCC1, and thymidine phosphorylase gene expression in primary and metastatic gastrointestinal adenocarcinoma tissue in patients treated on a phase I trial of oxaliplatin and capecitabine

BMC cancer, 2008-12, Vol.8 (1), p.386-386, Article 386

2008

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A Three-Gene Signature for Outcome in Soft Tissue Sarcoma

Clinical cancer research, 2009-08, Vol.15 (16), p.5191-5198

2009

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EGFR, FLT1 and heparanase as markers identifying patients at risk of short survival in cholangiocarcinoma

PloS one, 2013-05, Vol.8 (5), p.e64186-e64186

2013

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Vascular Endothelial Growth Factor Messenger RNA Expression Level Is Preserved in Liver Metastases Compared with Corresponding Primary Colorectal Cancer

Clinical cancer research, 2006-01, Vol.12 (1), p.29-33

2006

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Loss of Heterozygosity at the Thymidylate Synthase (TS) Locus on Chromosome 18 Affects Tumor Response and Survival in Individuals Heterozygous for a 28-bp Polymorphism in the TS Gene

Clinical cancer research, 2004-01, Vol.10 (2), p.433-439

2004

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Epidermal Growth Factor Receptor Messenger RNA Expression, Gene Dosage, and Gefitinib Sensitivity in Non–Small Cell Lung Cancer

Clinical cancer research, 2006-05, Vol.12 (10), p.3078-3084

2006

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HER‐2 receptor expression, localization, and activation in colorectal cancer cell lines and human tumors

International journal of cancer, 2004-02, Vol.108 (4), p.540-548

2004

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Gene profiling and pathway analysis of neuroendocrine transdifferentiated prostate cancer cells

The Prostate, 2009-01, Vol.69 (1), p.12-23

2009

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High Specificity of Quantitative Excision Repair Cross-Complementing 1 Messenger RNA Expression for Prediction of Minor Histopathological Response to Neoadjuvant Radiochemotherapy in Esophageal Cancer

Clinical cancer research, 2004-06, Vol.10 (11), p.3794-3799

2004

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Pharmacogenomics of thymidylate synthase in cancer treatment

Frontiers in bioscience, 2004-09, Vol.9, p.2484

Danenberg, Peter V

2004

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Osteopontin But Not Osteonectin Messenger RNA Expression Is a Prognostic Marker in Curatively Resected Non-Small Cell Lung Cancer

Clinical cancer research, 2004-03, Vol.10 (5), p.1588-1596

2004

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Functional Polymorphism of the Thymidylate Synthase Gene in Colorectal Cancer Accompanied by Frequent Loss of Heterozygosity

Cancer science, 2002-11, Vol.93 (11), p.1221-1229

2002

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Frequencies and expression levels of programmed death ligand 1 (PD-L1) in circulating tumor RNA (ctRNA) in various cancer types

Biochemical and biophysical research communications, 2018-06, Vol.500 (3), p.621-625

2018

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Increased CDX2 and decreased PITX1 homeobox gene expression in Barrett's esophagus and Barrett's-associated adenocarcinoma

Surgery, 2005-11, Vol.138 (5), p.924-931

2005

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MethyLight: a high-throughput assay to measure DNA methylation

Nucleic acids research, 2000-04, Vol.28 (8), p.E32

2000

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5‐fluorouracil‐related gene expression levels in primary colorectal cancer and corresponding liver metastasis

International journal of cancer, 2006-08, Vol.119 (3), p.522-526

2006

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Standing the test of time: targeting thymidylate biosynthesis in cancer therapy

ERCC1 and Thymidylate Synthase mRNA Levels Predict Survival for Colorectal Cancer Patients Receiving Combination Oxaliplatin and Fluorouracil Chemotherapy

MDR1 and ERCC1 Expression Predict Outcome of Patients with Locally Advanced Bladder Cancer Receiving Adjuvant Chemotherapy

An In vivo Platform for Translational Drug Development in Pancreatic Cancer

Folates as adjuvants to anticancer agents: chemical rationale and mechanism of action

Epidermal Growth Factor Receptor and HER2-neu mRNA Expression in Non-Small Cell Lung Cancer Is Correlated with Survival

High Expression of HIF1a Is a Predictor of Clinical Outcome in Patients with Pancreatic Ductal Adenocarcinomas and Correlated to PDGFA, VEGF, and bFGF

High Gene Expression of TS1, GSTP1, and ERCC1 Are Risk Factors for Survival in Patients Treated with Trimodality Therapy for Esophageal Cancer

Different Lengths of a Polymorphic Repeat Sequence in the Thymidylate Synthase Gene Affect Translational Efficiency but Not Its Gene Expression

Thymidylate synthase, dihydropyrimidine dehydrogenase, ERCC1, and thymidine phosphorylase gene expression in primary and metastatic gastrointestinal adenocarcinoma tissue in patients treated on a phase I trial of oxaliplatin and capecitabine

A Three-Gene Signature for Outcome in Soft Tissue Sarcoma

EGFR, FLT1 and heparanase as markers identifying patients at risk of short survival in cholangiocarcinoma

Vascular Endothelial Growth Factor Messenger RNA Expression Level Is Preserved in Liver Metastases Compared with Corresponding Primary Colorectal Cancer

Loss of Heterozygosity at the Thymidylate Synthase (TS) Locus on Chromosome 18 Affects Tumor Response and Survival in Individuals Heterozygous for a 28-bp Polymorphism in the TS Gene

Epidermal Growth Factor Receptor Messenger RNA Expression, Gene Dosage, and Gefitinib Sensitivity in Non–Small Cell Lung Cancer

HER‐2 receptor expression, localization, and activation in colorectal cancer cell lines and human tumors

Gene profiling and pathway analysis of neuroendocrine transdifferentiated prostate cancer cells

High Specificity of Quantitative Excision Repair Cross-Complementing 1 Messenger RNA Expression for Prediction of Minor Histopathological Response to Neoadjuvant Radiochemotherapy in Esophageal Cancer

Pharmacogenomics of thymidylate synthase in cancer treatment

Osteopontin But Not Osteonectin Messenger RNA Expression Is a Prognostic Marker in Curatively Resected Non-Small Cell Lung Cancer

Functional Polymorphism of the Thymidylate Synthase Gene in Colorectal Cancer Accompanied by Frequent Loss of Heterozygosity

Frequencies and expression levels of programmed death ligand 1 (PD-L1) in circulating tumor RNA (ctRNA) in various cancer types

Increased CDX2 and decreased PITX1 homeobox gene expression in Barrett's esophagus and Barrett's-associated adenocarcinoma

MethyLight: a high-throughput assay to measure DNA methylation

5‐fluorouracil‐related gene expression levels in primary colorectal cancer and corresponding liver metastasis

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