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SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells

The FASEB journal, 2019-03, Vol.33 (3), p.3704-3717

2019

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Pharmacological Sirt6 inhibition improves glucose tolerance in a type 2 diabetes mouse model

The FASEB journal, 2017-07, Vol.31 (7), p.3138-3149

2017

Volltextzugriff (PDF)

Fasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition

Oncotarget, 2015-05, Vol.6 (14), p.11820-11832

2015

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Nicotinamide Phosphoribosyltransferase Promotes Epithelial-to-Mesenchymal Transition as a Soluble Factor Independent of Its Enzymatic Activity

The Journal of biological chemistry, 2014-12, Vol.289 (49), p.34189-34204

2014

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In vivo generation of decidual natural killer cells from resident hematopoietic progenitors

Haematologica (Roma), 2014-03, Vol.99 (3), p.448

2014

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SIRT6 enhances oxidative phosphorylation in breast cancer and promotes mammary tumorigenesis in mice

Cancer & metabolism, 2021-01, Vol.9 (1), p.6-6, Article 6

2021

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Nicotinamide phosphoribosyltransferase as a target in inflammation- related disorders

Current topics in medicinal chemistry, 2013-12, Vol.13 (23), p.2930

2013

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Rapamycin Inhibits Growth of Premalignant and Malignant Mammary Lesions in a Mouse Model of Ductal Carcinoma In situ

Clinical cancer research, 2006-04, Vol.12 (8), p.2613-2621

2006

Volltextzugriff (PDF)

SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells

The FASEB journal, 2019-03, Vol.33 (3), p.3704-3717

2019

Volltextzugriff (PDF)

Increased Arginase1 expression in tumor microenvironment promotes mammary carcinogenesis via multiple mechanisms

Carcinogenesis (New York), 2020-12, Vol.41 (12), p.1695-1702

2020

Volltextzugriff (PDF)

Discovery of Novel and Selective SIRT6 Inhibitors

Journal of medicinal chemistry, 2014-06, Vol.57 (11), p.4796-4804

2014

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SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects

Bioorganic & medicinal chemistry, 2017-10, Vol.25 (20), p.5849-5858

2017

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Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics

European journal of medicinal chemistry, 2015-09, Vol.102, p.530-539

2015

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Abstract 4461: Sirt6 deletion slows mouse mammary tumorigenesis

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.4461-4461

2018

Volltextzugriff (PDF)

Sirt6 regulates dendritic cell differentiation, maturation, and function

Aging (Albany, NY.), 2016-01, Vol.8 (1), p.34-47

2016

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Transgenic mice overexpressing arginase 1 in monocytic cell lineage are affected by lympho-myeloproliferative disorders and disseminated intravascular coagulation

Carcinogenesis (New York), 2015-11, Vol.36 (11), p.1354-1362

2015

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EMT tumorigenesis in the mouse mammary gland

Laboratory investigation, 2007-12, Vol.87 (12), p.1218-1226

2007

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Epithelial-–mesenchymal transition in mouse mammary tumorigenesis

Future oncology (London, England), 2009-10, Vol.5 (8), p.1113-1127

2009

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Fate of embryonal carcinoma cells injected into postimplantation mouse embryos

Differentiation (London), 2005-12, Vol.73 (9), p.484-490

2005

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Mammary carcinoma behavior is programmed in the precancer stem cell

Breast cancer research : BCR, 2008-01, Vol.10 (3), p.R50-R50, Article R50

2008

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Inhibition of ductal morphogenesis in the mammary gland of WAP -fgf4 transgenic mice

Anatomy and Embryology, 2003-05, Vol.206 (6), p.471

2003

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Di-acetyl creatine ethyl ester, a new creatine derivative for the possible treatment of creatine transporter deficiency

Neuroscience letters, 2018-02, Vol.665, p.217-223

2018

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A Bioactive Olive Pomace Extract Prevents the Death of Murine Cortical Neurons Triggered by NMDAR Over-Activation

Molecules (Basel, Switzerland), 2020-09, Vol.25 (19), p.4385

2020

Volltextzugriff (PDF)

Effects on Energy Metabolism of Two Guanidine Molecules, (Boc)2‐Creatine and Metformin

Journal of cellular biochemistry, 2017-09, Vol.118 (9), p.2700-2711

2017

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Bioactive molecules isolated from olive pomace extract protect murine cortex neurons from NMDA‐mediated cell death

The FASEB journal, 2019-04, Vol.33 (S1), p.lb227-lb227

2019

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SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells

Pharmacological Sirt6 inhibition improves glucose tolerance in a type 2 diabetes mouse model

Fasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition

Nicotinamide Phosphoribosyltransferase Promotes Epithelial-to-Mesenchymal Transition as a Soluble Factor Independent of Its Enzymatic Activity

In vivo generation of decidual natural killer cells from resident hematopoietic progenitors

SIRT6 enhances oxidative phosphorylation in breast cancer and promotes mammary tumorigenesis in mice

Nicotinamide phosphoribosyltransferase as a target in inflammation- related disorders

Rapamycin Inhibits Growth of Premalignant and Malignant Mammary Lesions in a Mouse Model of Ductal Carcinoma In situ

SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells

Increased Arginase1 expression in tumor microenvironment promotes mammary carcinogenesis via multiple mechanisms

Discovery of Novel and Selective SIRT6 Inhibitors

SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects

Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics

Abstract 4461: Sirt6 deletion slows mouse mammary tumorigenesis

Sirt6 regulates dendritic cell differentiation, maturation, and function

Transgenic mice overexpressing arginase 1 in monocytic cell lineage are affected by lympho-myeloproliferative disorders and disseminated intravascular coagulation

EMT tumorigenesis in the mouse mammary gland

Epithelial-–mesenchymal transition in mouse mammary tumorigenesis

Fate of embryonal carcinoma cells injected into postimplantation mouse embryos

Mammary carcinoma behavior is programmed in the precancer stem cell

Inhibition of ductal morphogenesis in the mammary gland of WAP -fgf4 transgenic mice

Di-acetyl creatine ethyl ester, a new creatine derivative for the possible treatment of creatine transporter deficiency

A Bioactive Olive Pomace Extract Prevents the Death of Murine Cortical Neurons Triggered by NMDAR Over-Activation

Effects on Energy Metabolism of Two Guanidine Molecules, (Boc)2‐Creatine and Metformin

Bioactive molecules isolated from olive pomace extract protect murine cortex neurons from NMDA‐mediated cell death

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