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Next-Generation Sequencing: From Basic Research to Diagnostics

Clinical chemistry (Baltimore, Md.), 2009-04, Vol.55 (4), p.641-658

2009

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Nanoparticle Emission Assessment Technique (NEAT) for the Identification and Measurement of Potential Inhalation Exposure to Engineered Nanomaterials-Part B: Results from 12 Field Studies

Journal of occupational and environmental hygiene, 2010-03, Vol.7 (3), p.163-176

2010

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Evolutionary and genomic perspectives of brain aging and neurodegenerative diseases

From Fossils to Mind, 2023, Vol.275, p.165-215

2023

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Oxidative Unfolding of the Rubredoxin Domain and the Natively Disordered N-terminal Region Regulate the Catalytic Activity of Mycobacterium tuberculosis Protein Kinase G

The Journal of biological chemistry, 2016-12, Vol.291 (53), p.27062-27072

2016

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Structural Basis for the Association of the Redox-sensitive Target of Rapamycin FATC Domain with Membrane-mimetic Micelles

The Journal of biological chemistry, 2010-03, Vol.285 (10), p.7766-7775

Dames, Sonja A.

2010

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Transcription, structure, and organoids translate time across the lifespan of humans and great apes

PNAS nexus, 2023-08, Vol.2 (8), p.pgad230

2023

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Structural Basis for Hif-1α/CBP Recognition in the Cellular Hypoxic Response

Proceedings of the National Academy of Sciences - PNAS, 2002-04, Vol.99 (8), p.5271-5276

2002

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The Solution Structure of the FATC Domain of the Protein Kinase Target of Rapamycin Suggests a Role for Redox-dependent Structural and Cellular Stability

The Journal of biological chemistry, 2005-05, Vol.280 (21), p.20558-20564

2005

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Going beyond established model systems of Alzheimer’s disease: companion animals provide novel insights into the neurobiology of aging

Communications biology, 2023-06, Vol.6 (1), p.655-655, Article 655

2023

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A rapid gene sequencing panel strategy to facilitate precision neonatal medicine

American journal of medical genetics. Part A, 2017-07, Vol.173 (7), p.1979-1982

2017

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Targeted gene panel sequencing for the rapid diagnosis of acutely ill infants

Molecular genetics & genomic medicine, 2019-07, Vol.7 (7), p.e00796-n/a

2019

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Regulation of the Target of Rapamycin and Other Phosphatidylinositol 3-Kinase-Related Kinases by Membrane Targeting

Membranes (Basel), 2015-09, Vol.5 (4), p.553-575

2015

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Structure of the Cyclin T binding domain of Hexim1 and molecular basis for its recognition of P-TEFb

Proceedings of the National Academy of Sciences - PNAS, 2007-09, Vol.104 (36), p.14312-14317

2007

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Structural characterization of the antimicrobial peptides myxinidin and WMR in bacterial membrane mimetic micelles and bicelles

Biochimica et biophysica acta. Biomembranes, 2024-03, Vol.1866 (3), p.184272-184272, Article 184272

2024

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Insights into the Low Adhesive Capacity of Human T-cadherin from the NMR Structure of Its N-terminal Extracellular Domain

The Journal of biological chemistry, 2008-08, Vol.283 (34), p.23485-23495

2008

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The pedagogical role of multicultural leadership in post-apartheid South Africa

Hervormde teologiese studies, 2014-01, Vol.70 (1), p.01-09

2014

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NMR analysis of the backbone dynamics of the small GTPase Rheb and its interaction with the regulatory protein FKBP38

FEBS letters, 2018-01, Vol.592 (1), p.130-146

2018

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A Rigorous and Efficient Method To Reweight Very Large Conformational Ensembles Using Average Experimental Data and To Determine Their Relative Information Content

Journal of chemical theory and computation, 2016-01, Vol.12 (1), p.383-394

2016

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NMR– and MD simulation–based structural characterization of the membrane-associating FATC domain of ataxia telangiectasia mutated

The Journal of biological chemistry, 2019-04, Vol.294 (17), p.7098-7112

2019

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Expression and purification of the natively disordered and redox sensitive metal binding regions of Mycobacterium tuberculosis protein kinase G

Protein expression and purification, 2015-07, Vol.111, p.68-74

2015

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One short cysteine-rich sequence pattern - two different disulfide-bonded structures - a molecular dynamics simulation study

Journal of peptide science, 2015-06, Vol.21 (6), p.480-494

Dames, Sonja A.

2015

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Target of rapamycin FATC domain as a general membrane anchor: The FKBP‐12 like domain of FKBP38 as a case study

Protein science, 2018-02, Vol.27 (2), p.546-560

2018

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NMR- and Circular Dichroism-monitored Lipid Binding Studies Suggest a General Role for the FATC Domain as Membrane Anchor of Phosphatidylinositol 3-Kinase-related Kinases (PIKK)

The Journal of biological chemistry, 2013-07, Vol.288 (27), p.20046-20063

2013

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Characterization of residue-dependent differences in the peripheral membrane association of the FATC domain of the kinase ‘target of rapamycin’ by NMR and CD spectroscopy

FEBS letters, 2014-05, Vol.588 (9), p.1755-1766

2014

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A decade of surf-zone linefish monitoring in the Dwesa-Cwebe Marine Protected Area, with a preliminary assessment of the effects of rezoning and resource use

African journal of marine science, 2021-07, Vol.43 (3), p.309-323

2021

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Next-Generation Sequencing: From Basic Research to Diagnostics

Nanoparticle Emission Assessment Technique (NEAT) for the Identification and Measurement of Potential Inhalation Exposure to Engineered Nanomaterials-Part B: Results from 12 Field Studies

Evolutionary and genomic perspectives of brain aging and neurodegenerative diseases

Oxidative Unfolding of the Rubredoxin Domain and the Natively Disordered N-terminal Region Regulate the Catalytic Activity of Mycobacterium tuberculosis Protein Kinase G

Structural Basis for the Association of the Redox-sensitive Target of Rapamycin FATC Domain with Membrane-mimetic Micelles

Transcription, structure, and organoids translate time across the lifespan of humans and great apes

Structural Basis for Hif-1α/CBP Recognition in the Cellular Hypoxic Response

The Solution Structure of the FATC Domain of the Protein Kinase Target of Rapamycin Suggests a Role for Redox-dependent Structural and Cellular Stability

Going beyond established model systems of Alzheimer’s disease: companion animals provide novel insights into the neurobiology of aging

A rapid gene sequencing panel strategy to facilitate precision neonatal medicine

Targeted gene panel sequencing for the rapid diagnosis of acutely ill infants

Regulation of the Target of Rapamycin and Other Phosphatidylinositol 3-Kinase-Related Kinases by Membrane Targeting

Structure of the Cyclin T binding domain of Hexim1 and molecular basis for its recognition of P-TEFb

Structural characterization of the antimicrobial peptides myxinidin and WMR in bacterial membrane mimetic micelles and bicelles

Insights into the Low Adhesive Capacity of Human T-cadherin from the NMR Structure of Its N-terminal Extracellular Domain

The pedagogical role of multicultural leadership in post-apartheid South Africa

NMR analysis of the backbone dynamics of the small GTPase Rheb and its interaction with the regulatory protein FKBP38

A Rigorous and Efficient Method To Reweight Very Large Conformational Ensembles Using Average Experimental Data and To Determine Their Relative Information Content

NMR– and MD simulation–based structural characterization of the membrane-associating FATC domain of ataxia telangiectasia mutated

Expression and purification of the natively disordered and redox sensitive metal binding regions of Mycobacterium tuberculosis protein kinase G

One short cysteine-rich sequence pattern - two different disulfide-bonded structures - a molecular dynamics simulation study

Target of rapamycin FATC domain as a general membrane anchor: The FKBP‐12 like domain of FKBP38 as a case study

NMR- and Circular Dichroism-monitored Lipid Binding Studies Suggest a General Role for the FATC Domain as Membrane Anchor of Phosphatidylinositol 3-Kinase-related Kinases (PIKK)

Characterization of residue-dependent differences in the peripheral membrane association of the FATC domain of the kinase ‘target of rapamycin’ by NMR and CD spectroscopy

A decade of surf-zone linefish monitoring in the Dwesa-Cwebe Marine Protected Area, with a preliminary assessment of the effects of rezoning and resource use

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