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Affinity Enhancement of Protein Ligands by Reversible Covalent Modification of Neighboring Lysine Residues

Angewandte Chemie International Edition, 2018-12, Vol.57 (52), p.17178-17182

International ed. in English, 2018

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Protease-Cleavable Linkers Modulate the Anticancer Activity of Noninternalizing Antibody–Drug Conjugates

Bioconjugate chemistry, 2017-07, Vol.28 (7), p.1826-1833

2017

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Neutrophil Elastase Promotes Linker Cleavage and Paclitaxel Release from an Integrin‐Targeted Conjugate

Chemistry : a European journal, 2019-02, Vol.25 (7), p.1696-1700

2019

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A dimeric bicyclic RGD ligand displays enhanced integrin binding affinity and strong biological effects on U-373 MG glioblastoma cells

Organic & biomolecular chemistry, 2019-10, Vol.17 (39), p.8913-8917

2019

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Targeted Delivery of Cytotoxic Drugs: Challenges, Opportunities and New Developments

Chimia, 2017-10, Vol.71 (10), p.712

2017

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Linker stability influences the anti-tumor activity of acetazolamide-drug conjugates for the therapy of renal cell carcinoma

Journal of controlled release, 2017-01, Vol.246, p.39-45

2017

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Innovative Linker Strategies for Tumor‐Targeted Drug Conjugates

Chemistry : a European journal, 2019-11, Vol.25 (65), p.14740-14757

2019

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Targeted Small‐Molecule Conjugates: The Future is Now

Chembiochem : a European journal of chemical biology, 2020-12, Vol.21 (23), p.3321-3322

Dal Corso, Alberto

2020

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Chemically Defined Antibody– and Small Molecule–Drug Conjugates for in Vivo Tumor Targeting Applications: A Comparative Analysis

Journal of the American Chemical Society, 2018-02, Vol.140 (5), p.1617-1621

2018

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Synthesis and Biological Evaluation of RGD and isoDGR–Monomethyl Auristatin Conjugates Targeting Integrin αVβ3

ChemMedChem, 2019-05, Vol.14 (9), p.938-942

2019

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Fast Cyclization of a Proline‐Derived Self‐Immolative Spacer Improves the Efficacy of Carbamate Prodrugs

Angewandte Chemie International Edition, 2020-03, Vol.59 (10), p.4176-4181

International ed. in English, 2020

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Synthesis of Noncoded Amino Acids Bearing a Salicylaldehyde Tag for the Design of Reversible‐Covalent Peptides

European journal of organic chemistry, 2024-06, Vol.27 (22), p.n/a

2024

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A Tight Contact: The Expanding Application of Salicylaldehydes in Lysine‐Targeting Covalent Drugs

Chembiochem : a European journal of chemical biology, 2024-04, Vol.25 (7), p.e202300743-n/a

2024

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A trifunctional self-immolative spacer enables drug release with two non-sequential enzymatic cleavages

Chemical communications (Cambridge, England), 2021-08, Vol.57 (63), p.7778-7781

2021

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Functionalized 2‐Hydroxybenzaldehyde‐PEG Modules as Portable Tags for the Engagement of Protein Lysine ϵ‐Amino Groups

European journal of organic chemistry, 2021-03, Vol.2021 (11), p.1763-1767

2021

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RGD Cyclopeptide Equipped with a Lysine‐Engaging Salicylaldehyde Showing Enhanced Integrin Affinity and Cell Detachment Potency

Chemistry : a European journal, 2023-04, Vol.29 (19), p.e202203768-n/a

2023

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Advanced Pyrrolidine‐Carbamate Self‐Immolative Spacer with Tertiary Amine Handle Induces Superfast Cyclative Drug Release

ChemMedChem, 2022-08, Vol.17 (15), p.e202200279-n/a

2022

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Frontispiece: Innovative Linker Strategies for Tumor‐Targeted Drug Conjugates

Chemistry : a European journal, 2019-11, Vol.25 (65), p.n/a

2019

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Metallaphotoredox C−O and C−N Cross‐Coupling Using Donor‐Acceptor Cyanoarene Photocatalysts

ChemCatChem, 2022-12, Vol.14 (23), p.n/a

2022

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Multimeric Presentation of RGD Peptidomimetics Enhances Integrin Binding and Tumor Cell Uptake

Chemistry : a European journal, 2020-06, Vol.26 (33), p.7492-7496

2020

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Amine‐Carbamate Self‐Immolative Spacers Counterintuitively Release 3° Alcohol at Much Faster Rates than 1° Alcohol Payloads

Chembiochem : a European journal of chemical biology, 2024-04, Vol.25 (8), p.e202400174-n/a

2024

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Synthesis and Biological Evaluation of RGD Peptidomimetic-Paclitaxel Conjugates Bearing Lysosomally Cleavable Linkers

Chemistry : a European journal, 2015-04, Vol.21 (18), p.6921-6929

2015

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Multivalency Increases the Binding Strength of RGD Peptidomimetic‐Paclitaxel Conjugates to Integrin αVβ3

Chemistry : a European journal, 2017-10, Vol.23 (58), p.14410-14415

2017

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Cyclic isoDGR and RGD Peptidomimetics Containing Bifunctional Diketopiperazine Scaffolds are Integrin Antagonists

Chemistry : a European journal, 2015-04, Vol.21 (16), p.6265-6271

2015

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Impact of a Central Scaffold on the Binding Affinity of Fragment Pairs Isolated from DNA‐Encoded Self‐Assembling Chemical Libraries

ChemMedChem, 2017-11, Vol.12 (21), p.1748-1752

2017

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Affinity Enhancement of Protein Ligands by Reversible Covalent Modification of Neighboring Lysine Residues

Protease-Cleavable Linkers Modulate the Anticancer Activity of Noninternalizing Antibody–Drug Conjugates

Neutrophil Elastase Promotes Linker Cleavage and Paclitaxel Release from an Integrin‐Targeted Conjugate

A dimeric bicyclic RGD ligand displays enhanced integrin binding affinity and strong biological effects on U-373 MG glioblastoma cells

Targeted Delivery of Cytotoxic Drugs: Challenges, Opportunities and New Developments

Linker stability influences the anti-tumor activity of acetazolamide-drug conjugates for the therapy of renal cell carcinoma

Innovative Linker Strategies for Tumor‐Targeted Drug Conjugates

Targeted Small‐Molecule Conjugates: The Future is Now

Chemically Defined Antibody– and Small Molecule–Drug Conjugates for in Vivo Tumor Targeting Applications: A Comparative Analysis

Synthesis and Biological Evaluation of RGD and isoDGR–Monomethyl Auristatin Conjugates Targeting Integrin αVβ3

Fast Cyclization of a Proline‐Derived Self‐Immolative Spacer Improves the Efficacy of Carbamate Prodrugs

Synthesis of Noncoded Amino Acids Bearing a Salicylaldehyde Tag for the Design of Reversible‐Covalent Peptides

A Tight Contact: The Expanding Application of Salicylaldehydes in Lysine‐Targeting Covalent Drugs

A trifunctional self-immolative spacer enables drug release with two non-sequential enzymatic cleavages

Functionalized 2‐Hydroxybenzaldehyde‐PEG Modules as Portable Tags for the Engagement of Protein Lysine ϵ‐Amino Groups

RGD Cyclopeptide Equipped with a Lysine‐Engaging Salicylaldehyde Showing Enhanced Integrin Affinity and Cell Detachment Potency

Advanced Pyrrolidine‐Carbamate Self‐Immolative Spacer with Tertiary Amine Handle Induces Superfast Cyclative Drug Release

Frontispiece: Innovative Linker Strategies for Tumor‐Targeted Drug Conjugates

Metallaphotoredox C−O and C−N Cross‐Coupling Using Donor‐Acceptor Cyanoarene Photocatalysts

Multimeric Presentation of RGD Peptidomimetics Enhances Integrin Binding and Tumor Cell Uptake

Amine‐Carbamate Self‐Immolative Spacers Counterintuitively Release 3° Alcohol at Much Faster Rates than 1° Alcohol Payloads

Synthesis and Biological Evaluation of RGD Peptidomimetic-Paclitaxel Conjugates Bearing Lysosomally Cleavable Linkers

Multivalency Increases the Binding Strength of RGD Peptidomimetic‐Paclitaxel Conjugates to Integrin αVβ3

Cyclic isoDGR and RGD Peptidomimetics Containing Bifunctional Diketopiperazine Scaffolds are Integrin Antagonists

Impact of a Central Scaffold on the Binding Affinity of Fragment Pairs Isolated from DNA‐Encoded Self‐Assembling Chemical Libraries

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