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The Abl/Abi signaling links WAVE regulatory complex to Cbl E3 ubiquitin ligase and is essential for breast cancer cell metastasis

Neoplasia (New York, N.Y.), 2022-10, Vol.32, p.100819-100819, Article 100819

2022

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Knockdown of VEGF receptor-1 (VEGFR-1) impairs macrophage infiltration, angiogenesis and growth of clear cell renal cell carcinoma (CRCC)

Cancer biology & therapy, 2011-11, Vol.12 (10), p.872-880

2011

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CRISPR/CAS9-mediated knockout of Abi1 inhibits p185Bcr-Abl-induced leukemogenesis and signal transduction to ERK and PI3K/Akt pathways

Journal of hematology and oncology, 2020-04, Vol.13 (1), p.1-12, Article 34

2020

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Increasing extracellular matrix collagen level and MMP activity induces cyst development in polycystic kidney disease

BMC nephrology, 2012-09, Vol.13 (1), p.109-109, Article 109

2012

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Abl interactor 1 regulates Src-Id1-matrix metalloproteinase 9 axis and is required for invadopodia formation, extracellular matrix degradation and tumor growth of human breast cancer cells

Carcinogenesis (New York), 2009-12, Vol.30 (12), p.2109-2116

2009

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G-protein coupled receptor 34 activates Erk and phosphatidylinositol 3-kinase/Akt pathways and functions as alternative pathway to mediate p185Bcr-Abl-induced transformation and leukemogenesis

Leukemia & lymphoma, 2015-07, Vol.56 (7), p.2170-2181

2015

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Imatinib-Associated Fluid Retention: FR-PO271

Journal of the American Society of Nephrology, 2023-11, Vol.34 (11S), p.479-479

2023

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Bcr-Abl induces abnormal cytoskeleton remodeling, β1 integrin clustering and increased cell adhesion to fibronectin through the Abl interactor 1 pathway

Journal of cell science, 2007-04, Vol.120 (8), p.1436-1446

2007

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CRISPR/CAS9-mediated knockout of Abi1 inhibits p185 Bcr-Abl -induced leukemogenesis and signal transduction to ERK and PI3K/Akt pathways

Journal of hematology and oncology, 2020-04, Vol.13 (1), p.34

2020

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Deletion of the Src Homology 3 Domain and C-terminal Proline-rich Sequences in Bcr-Abl Prevents Abl Interactor 2 Degradation and Spontaneous Cell Migration and Impairs Leukemogenesis

The Journal of biological chemistry, 2001-08, Vol.276 (31), p.28954-28960

2001

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Abstract P2-05-18: Deregulation of the Abl interactor 1 signaling as a potential biomarker for metastatic breast cancer

Cancer research (Chicago, Ill.), 2012-12, Vol.72 (24_Supplement), p.P2-P2-05-18

2012

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CDK1-mediated Phosphorylation of Abi1 Attenuates Bcr-Abl-induced F-actin Assembly and Tyrosine Phosphorylation of WAVE Complex during Mitosis

The Journal of biological chemistry, 2011-11, Vol.286 (44), p.38614-38626

2011

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Inhibition of class II phosphoinositide 3-kinase gamma expression by p185(Bcr-Abl) contributes to impaired chemotaxis and aberrant homing of leukemic cells

Leukemia & lymphoma, 2010-06, Vol.51 (6), p.1098

2010

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Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity

Genes & development, 1995-11, Vol.9 (21), p.2569-2582

1995

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Inhibition of class II phosphoinositide 3-kinase γ expression by p185Bcr-Abl contributes to impaired chemotaxis and aberrant homing of leukemic cells

Leukemia & lymphoma, 2010-06, Vol.51 (6), p.1098-1107

2010

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MT1-MMP as a downstream target of BCR-ABL ABL interactor 1 signaling: polarized distribution and involvement in BCR-ABL-stimulated leukemic cell migration

Leukemia, 2008-05, Vol.22 (5), p.1053-1056

2008

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Synthesis and regulation of insulin-like growth factor binding protein-5 in FRTL-5 cells

Endocrinology (Philadelphia), 1993-04, Vol.132 (4), p.1677-1681

1993

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Abil gene silencing by short hairpin RNA impairs Bcr-Abl-induced cell adhesion and migration in vitro and leukemogenesis in vivo

Carcinogenesis (New York), 2008, Vol.29 (9), p.1717-1724

2008

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Bcr-Abl induces abnormal cytoskeleton remodeling, beta1 integrin clustering and increased cell adhesion to fibronectin through the Abl interactor 1 pathway

Journal of cell science, 2007-04, Vol.120 (Pt 8), p.1436-1446

2007

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BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein

Cell, 1993, Vol.75 (1), p.175-185

1993

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Dysregulation of Actin Polymerization in Hematopoietic Cells Transformed by Bcr-Abl

Blood, 2004-11, Vol.104 (11), p.2568-2568

2004

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Oncogenic Abl and Src tyrosine kinases elicit the ubiquitin-dependent degradation of target proteins through a Ras-independent pathway

Genes & development, 1998-05, Vol.12 (10), p.1415-1424

1998

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In vivo actions of insulin-like growth factor-I (IGF-I) on cerebellum development in transgenic mice: evidence that IGF-I increases proliferation of granule cell progenitors

Brain research. Developmental brain research, 1996-08, Vol.95 (1), p.44-54

1996

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Human insulin-like growth factor-binding protein-1 (hIGFBP-1) in transgenic mice: characterization and insights into the regulation of IGFBP-1 expression

Endocrinology (Philadelphia), 1994-10, Vol.135 (4), p.1316-1327

1994

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Mechanisms of IGF-I autocrine action: Studies using transgenic model systems

Dai, Zonghan

1992

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The Abl/Abi signaling links WAVE regulatory complex to Cbl E3 ubiquitin ligase and is essential for breast cancer cell metastasis

Knockdown of VEGF receptor-1 (VEGFR-1) impairs macrophage infiltration, angiogenesis and growth of clear cell renal cell carcinoma (CRCC)

CRISPR/CAS9-mediated knockout of Abi1 inhibits p185Bcr-Abl-induced leukemogenesis and signal transduction to ERK and PI3K/Akt pathways

Increasing extracellular matrix collagen level and MMP activity induces cyst development in polycystic kidney disease

Abl interactor 1 regulates Src-Id1-matrix metalloproteinase 9 axis and is required for invadopodia formation, extracellular matrix degradation and tumor growth of human breast cancer cells

G-protein coupled receptor 34 activates Erk and phosphatidylinositol 3-kinase/Akt pathways and functions as alternative pathway to mediate p185Bcr-Abl-induced transformation and leukemogenesis

Imatinib-Associated Fluid Retention: FR-PO271

Bcr-Abl induces abnormal cytoskeleton remodeling, β1 integrin clustering and increased cell adhesion to fibronectin through the Abl interactor 1 pathway

CRISPR/CAS9-mediated knockout of Abi1 inhibits p185 Bcr-Abl -induced leukemogenesis and signal transduction to ERK and PI3K/Akt pathways

Deletion of the Src Homology 3 Domain and C-terminal Proline-rich Sequences in Bcr-Abl Prevents Abl Interactor 2 Degradation and Spontaneous Cell Migration and Impairs Leukemogenesis

Abstract P2-05-18: Deregulation of the Abl interactor 1 signaling as a potential biomarker for metastatic breast cancer

CDK1-mediated Phosphorylation of Abi1 Attenuates Bcr-Abl-induced F-actin Assembly and Tyrosine Phosphorylation of WAVE Complex during Mitosis

Inhibition of class II phosphoinositide 3-kinase gamma expression by p185(Bcr-Abl) contributes to impaired chemotaxis and aberrant homing of leukemic cells

Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity

Inhibition of class II phosphoinositide 3-kinase γ expression by p185Bcr-Abl contributes to impaired chemotaxis and aberrant homing of leukemic cells

MT1-MMP as a downstream target of BCR-ABL ABL interactor 1 signaling: polarized distribution and involvement in BCR-ABL-stimulated leukemic cell migration

Synthesis and regulation of insulin-like growth factor binding protein-5 in FRTL-5 cells

Abil gene silencing by short hairpin RNA impairs Bcr-Abl-induced cell adhesion and migration in vitro and leukemogenesis in vivo

Bcr-Abl induces abnormal cytoskeleton remodeling, beta1 integrin clustering and increased cell adhesion to fibronectin through the Abl interactor 1 pathway

BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein

Dysregulation of Actin Polymerization in Hematopoietic Cells Transformed by Bcr-Abl

Oncogenic Abl and Src tyrosine kinases elicit the ubiquitin-dependent degradation of target proteins through a Ras-independent pathway

In vivo actions of insulin-like growth factor-I (IGF-I) on cerebellum development in transgenic mice: evidence that IGF-I increases proliferation of granule cell progenitors

Human insulin-like growth factor-binding protein-1 (hIGFBP-1) in transgenic mice: characterization and insights into the regulation of IGFBP-1 expression

Mechanisms of IGF-I autocrine action: Studies using transgenic model systems

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