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Simultaneous Determination of Four Iridoid Glycosides from Paederia Scandens in Rat Plasma by LC-MS/MS and its Application to a Pharmacokinetic Study

Current analytical chemistry, 2020, Vol.16 (3), p.298-307

2020

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Validation of visualized transgenic zebrafish as a high throughput model to assay bradycardia related cardio toxicity risk candidates

Journal of applied toxicology, 2012-10, Vol.32 (10), p.834-842

2012

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Different binding sites of bovine organic anion-transporting polypeptide1a2 are involved in the transport of different fluoroquinolones

Drug metabolism and disposition, 2014-08, Vol.42 (8), p.1261-1267

2014

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Development of an optimized cytotoxicity assay system for CYP3A4-mediated metabolic activation via modified piggyBac transposition

Toxicology in vitro, 2016-04, Vol.32, p.132-137

2016

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Drug-drug Interactions between Ketoconazole and Berberine in Rats: Pharmacokinetic Effects Benefit Pharmacodynamic Synergism

Phytotherapy research, 2012-05, Vol.26 (5), p.772-777

2012

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Simultaneous analysis of bambuterol and its active metabolite terbutaline enantiomers in rat plasma by chiral liquid chromatography–tandem mass spectrometry

Journal of pharmaceutical and biomedical analysis, 2010-06, Vol.52 (2), p.227-231

2010

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Development and full validation of six inhibition assays for five major cytochrome P450 enzymes in human liver microsomes using an automated 96-well microplate incubation format and LC–MS/MS analysis

Journal of pharmaceutical and biomedical analysis, 2007-05, Vol.44 (1), p.211-223

2007

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Cytochrome P450 3A-mediated metabolism of buspirone in human liver microsomes

Drug metabolism and disposition, 2005-04, Vol.33 (4), p.500-507

2005

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Myotoxicity of gemfibrozil in Cynomolgus monkey model and its relationship to pharmacokinetic properties

Toxicology and applied pharmacology, 2009-03, Vol.235 (3), p.287-295

2009

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Fenofibrate metabolism in the cynomolgus monkey using ultraperformance liquid chromatography-quadrupole time-of-flight mass spectrometry-based metabolomics

Drug metabolism and disposition, 2009-06, Vol.37 (6), p.1157-1163

2009

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Influence of two-period cross-over design on the bioequivalence study of gefitinib tablets in beagle dogs

European journal of pharmaceutical sciences, 2021-10, Vol.165, p.105933-105933, Article 105933

2021

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A Kinetic Model for the Metabolic Interaction of Two Substrates at the Active Site of Cytochrome P450 3A4

The Journal of biological chemistry, 2001-01, Vol.276 (3), p.2256-2262

2001

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Induction of P450 3A1/2 and 2C6 by gemfibrozil in Sprague-Dawley rats

Pharmacological reports, 2011-01, Vol.63 (1), p.157-164

2011

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Roles of diclofenac and its metabolites in immune activation associated with acute hepatotoxicity in TgCYP3A4/hPXR-humanized mice

International immunopharmacology, 2020-09, Vol.86, p.106723, Article 106723

2020

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Sigmoidal kinetic model for two co-operative substrate-binding sites in a cytochrome P450 3A4 active site: an example of the metabolism of diazepam and its derivatives

Biochemical journal, 1999-06, Vol.340 ( Pt 3) (3), p.845-853

1999

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Comparison of in vitro/in vivo blood distribution and pharmacokinetics of artemisinin, artemether and dihydroartemisinin in rats

Journal of pharmaceutical and biomedical analysis, 2019-01, Vol.162, p.140-148

2019

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Fluorescent metal–organic framework based on pyrene chromophore for sensing of nitrobenzene

RSC advances, 2015, Vol.5 (10), p.7121-7124

2015

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Studies on oral bioavailability and first‐pass metabolism of withaferin A in rats using LC–MS/MS and Q‐TRAP

Biomedical chromatography, 2019-09, Vol.33 (9), p.e4573-n/a

2019

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Interaction of the Human Immunodeficiency Virus Type 1 Nucleocapsid with Actin

Journal of Virology, 1999-04, Vol.73 (4), p.2901-2908

1999

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Inhibition effects of eight anti-coronavirus drugs on glycosides metabolism and glycosidases in human gut microflora

Pharmazie, 2021-05, Vol.76 (5), p.195-201

2021

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Study of Pharmacokinetics for Ivermectin B1a from Beagle Dogs

Journal of chromatographic science, 2023-12

2023

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Comparative inhibition of human cytochromes P450 1A1 and 1A2 by flavonoids

Drug metabolism and disposition, 1998-10, Vol.26 (10), p.989

1998

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Hypaconitine-induced QT prolongation mediated through inhibition of KCNH2 (hERG) potassium channels in conscious dogs

Journal of ethnopharmacology, 2015-05, Vol.166, p.375-379

2015

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Studies of pharmacokinetics in beagle dogs and drug-drug interaction potential of a novel selective ZAK inhibitor 3h for hypertrophic cardiomyopathy treatment

Journal of pharmaceutical and biomedical analysis, 2019-08, Vol.172, p.206-213

2019

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Metabolism, pharmacokinetics, and protein covalent binding of radiolabeled MaxiPost (BMS-204352) in humans

Drug metabolism and disposition, 2005-01, Vol.33 (1), p.83-93

2005

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Simultaneous Determination of Four Iridoid Glycosides from Paederia Scandens in Rat Plasma by LC-MS/MS and its Application to a Pharmacokinetic Study

Validation of visualized transgenic zebrafish as a high throughput model to assay bradycardia related cardio toxicity risk candidates

Different binding sites of bovine organic anion-transporting polypeptide1a2 are involved in the transport of different fluoroquinolones

Development of an optimized cytotoxicity assay system for CYP3A4-mediated metabolic activation via modified piggyBac transposition

Drug-drug Interactions between Ketoconazole and Berberine in Rats: Pharmacokinetic Effects Benefit Pharmacodynamic Synergism

Simultaneous analysis of bambuterol and its active metabolite terbutaline enantiomers in rat plasma by chiral liquid chromatography–tandem mass spectrometry

Development and full validation of six inhibition assays for five major cytochrome P450 enzymes in human liver microsomes using an automated 96-well microplate incubation format and LC–MS/MS analysis

Cytochrome P450 3A-mediated metabolism of buspirone in human liver microsomes

Myotoxicity of gemfibrozil in Cynomolgus monkey model and its relationship to pharmacokinetic properties

Fenofibrate metabolism in the cynomolgus monkey using ultraperformance liquid chromatography-quadrupole time-of-flight mass spectrometry-based metabolomics

Influence of two-period cross-over design on the bioequivalence study of gefitinib tablets in beagle dogs

A Kinetic Model for the Metabolic Interaction of Two Substrates at the Active Site of Cytochrome P450 3A4

Induction of P450 3A1/2 and 2C6 by gemfibrozil in Sprague-Dawley rats

Roles of diclofenac and its metabolites in immune activation associated with acute hepatotoxicity in TgCYP3A4/hPXR-humanized mice

Sigmoidal kinetic model for two co-operative substrate-binding sites in a cytochrome P450 3A4 active site: an example of the metabolism of diazepam and its derivatives

Comparison of in vitro/in vivo blood distribution and pharmacokinetics of artemisinin, artemether and dihydroartemisinin in rats

Fluorescent metal–organic framework based on pyrene chromophore for sensing of nitrobenzene

Studies on oral bioavailability and first‐pass metabolism of withaferin A in rats using LC–MS/MS and Q‐TRAP

Interaction of the Human Immunodeficiency Virus Type 1 Nucleocapsid with Actin

Inhibition effects of eight anti-coronavirus drugs on glycosides metabolism and glycosidases in human gut microflora

Study of Pharmacokinetics for Ivermectin B1a from Beagle Dogs

Comparative inhibition of human cytochromes P450 1A1 and 1A2 by flavonoids

Hypaconitine-induced QT prolongation mediated through inhibition of KCNH2 (hERG) potassium channels in conscious dogs

Studies of pharmacokinetics in beagle dogs and drug-drug interaction potential of a novel selective ZAK inhibitor 3h for hypertrophic cardiomyopathy treatment

Metabolism, pharmacokinetics, and protein covalent binding of radiolabeled MaxiPost (BMS-204352) in humans

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