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Exogenous hydrogen sulphide ameliorates diabetic cardiomyopathy in rats by reversing disordered calcium-handling system in sarcoplasmic reticulum

Journal of pharmacy and pharmacology, 2016-03, Vol.68 (3), p.379-388

2016

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Argirein alleviates stress-induced and diabetic hypogonadism in rats via normalizing testis endothelin receptor A and connexin 43

Acta pharmacologica Sinica, 2016-02, Vol.37 (2), p.246-254

2016

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Role of endothelin receptor A and NADPH oxidase in vascular abnormalities

Vascular health and risk management, 2010-01, Vol.6 (default), p.787-794

2010

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The separate roles of endothelin receptors participate in remodeling of matrix metalloproteinase and connexin 43 of cardiac fibroblasts in maladaptive response to isoproterenol

European journal of pharmacology, 2010-05, Vol.634 (1), p.101-106

2010

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Effects of strontium fructose 1,6-diphosphate on expression of apoptosis-related genes and oxidative stress in testes of diabetic rats

International journal of urology, 2008-03, Vol.15 (3), p.251-256

2008

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NaHS ameliorates diabetic vascular injury by correcting depressed connexin 43 and 40 in the vasculature in streptozotocin-injected rats

Journal of pharmacy and pharmacology, 2010-05, Vol.62 (5), p.615-621

2010

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Activation of AQP4, p66Shc and endoplasmic reticulum stress is involved in inflammation by carrageenan and is suppressed by argirein, a derivative of rhein

Journal of pharmacy and pharmacology, 2012-08, Vol.64 (8), p.1138-1145

2012

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David Triggle: Research collaborations and scientific exchanges with the China Pharmaceutical University, Nanjing, China

Biochemical pharmacology, 2015-11, Vol.98 (2), p.303-307

Dai, De-Zai

2015

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Endoplasmic reticulum stress mediating downregulated StAR and 3-beta-HSD and low plasma testosterone caused by hypoxia is attenuated by CPU86017-RS and nifedipine

Journal of biomedical science, 2012-01, Vol.19 (1), p.4-4, Article 4

2012

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Isoproterenol Induced Stressful Reactions in the Brain Are Characterized by Inflammation due to Activation of NADPH Oxidase and ER Stress: Attenuated by Apocynin, Rehmannia Complex and Triterpene Acids

Neurochemical research, 2014-04, Vol.39 (4), p.719-730

2014

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CPUY11018, an azimilide derivative, ameliorates isoproterenol-induced cardiac insufficiency through relieving dysfunctional mitochondria and endoplasmic reticulum

Journal of pharmacy and pharmacology, 2015-08, Vol.67 (8), p.1029-1041

2015

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Argirein alleviates corpus cavernosum dysfunction by suppressing pro-inflammatory factors p66Shc and ER stress chaperone Bip in diabetic rats

Journal of pharmacy and pharmacology, 2013-01, Vol.65 (1), p.94-101

2013

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Hepatosteatosis and hepatic insulin resistance are blunted by argirein, an anti-inflammatory agent, through normalizing endoplasmic reticulum stress and apoptosis in diabetic liver

Journal of pharmacy and pharmacology, 2013-06, Vol.65 (6), p.916-927

2013

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Sildenafil improves diabetic vascular activity through suppressing endothelin receptor A, iNOS and NADPH oxidase which is comparable with the endothelin receptor antagonist CPU0213 in STZ-injected rats

Journal of pharmacy and pharmacology, 2011-07, Vol.63 (7), p.943-951

2011

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UPREGULATED ENDOTHELIN SYSTEM IN DIABETIC VASCULAR DYSFUNCTION AND EARLY RETINOPATHY IS REVERSED BY CPU0213 AND TOTAL TRITERPENE ACIDS FROM FRUCTUS CORNI

Clinical and experimental pharmacology & physiology, 2007-12, Vol.34 (12), p.1228-1233

2007

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Hypoxia/oxidative stress alters the pharmacokinetics of CPU86017-RS through mitochondrial dysfunction and NADPH oxidase activation

Acta pharmacologica Sinica, 2013-12, Vol.34 (12), p.1575-1584

2013

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Hypoxia alters pharmacokinetics of argirein because of mitochondrial dysfunction that is alleviated by apocynin

Journal of pharmacy and pharmacology, 2013-09, Vol.65 (9), p.1360-1372

2013

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Total triterpene acids, active ingredients from Fructus Corni, attenuate diabetic cardiomyopathy by normalizing ET pathway and expression of FKBP12.6 and SERCA2a in streptozotocin-rats

Journal of pharmacy and pharmacology, 2008-12, Vol.60 (12), p.1687-1694

2008

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Apocynin and raisanberine alleviate intermittent hypoxia induced abnormal StAR and 3β-HSD and low testosterone by suppressing endoplasmic reticulum stress and activated p66Shc in rat testes

Reproductive toxicology (Elmsford, N.Y.), 2013-04, Vol.36, p.60-70

2013

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Stress-induced cardiac insufficiency relating to abnormal leptin and FKBP12.6 is ameliorated by CPU0213, an endothelin receptor antagonist, which is not affected by the CYP3A suppressing effect of erythromycin

Journal of pharmacy and pharmacology, 2009-05, Vol.61 (5), p.569-576

2009

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CPU86017, a berberine derivative, attenuates cardiac failure through normalizing calcium leakage and downregulated phospholamban and exerting antioxidant activity

Acta pharmacologica Sinica, 2010-02, Vol.31 (2), p.165-174

2010

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Role of endothelin in the effects of isoprenaline on potassium currents and calsequestrin 2 expression in the heart

Clinical and experimental pharmacology & physiology, 2010-05, Vol.37 (5-6), p.557-563

2010

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CPU0213, A NON-SELECTIVE ETA/ETB RECEPTOR ANTAGONIST, IMPROVES PULMONARY ARTERIOLAR REMODELING OF MONOCROTALINE-INDUCED PULMONARY HYPERTENSION IN RATS

Clinical and experimental pharmacology & physiology, 2009-02, Vol.36 (2), p.169-175

2009

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Sildenafil and FDP-Sr attenuate diabetic cardiomyopathy by suppressing abnormal expression of myocardial CASQ2, FKBP12.6, and SERCA2a in rats

Acta pharmacologica Sinica, 2011-04, Vol.32 (4), p.441-448

2011

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Raisanberine protected pulmonary arterial rings and cardiac myocytes of rats against hypoxia injury by suppressing NADPH oxidase and calcium influx

Acta pharmacologica Sinica, 2012-05, Vol.33 (5), p.625-634

2012

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Exogenous hydrogen sulphide ameliorates diabetic cardiomyopathy in rats by reversing disordered calcium-handling system in sarcoplasmic reticulum

Argirein alleviates stress-induced and diabetic hypogonadism in rats via normalizing testis endothelin receptor A and connexin 43

Role of endothelin receptor A and NADPH oxidase in vascular abnormalities

The separate roles of endothelin receptors participate in remodeling of matrix metalloproteinase and connexin 43 of cardiac fibroblasts in maladaptive response to isoproterenol

Effects of strontium fructose 1,6-diphosphate on expression of apoptosis-related genes and oxidative stress in testes of diabetic rats

NaHS ameliorates diabetic vascular injury by correcting depressed connexin 43 and 40 in the vasculature in streptozotocin-injected rats

Activation of AQP4, p66Shc and endoplasmic reticulum stress is involved in inflammation by carrageenan and is suppressed by argirein, a derivative of rhein

David Triggle: Research collaborations and scientific exchanges with the China Pharmaceutical University, Nanjing, China

Endoplasmic reticulum stress mediating downregulated StAR and 3-beta-HSD and low plasma testosterone caused by hypoxia is attenuated by CPU86017-RS and nifedipine

Isoproterenol Induced Stressful Reactions in the Brain Are Characterized by Inflammation due to Activation of NADPH Oxidase and ER Stress: Attenuated by Apocynin, Rehmannia Complex and Triterpene Acids

CPUY11018, an azimilide derivative, ameliorates isoproterenol-induced cardiac insufficiency through relieving dysfunctional mitochondria and endoplasmic reticulum

Argirein alleviates corpus cavernosum dysfunction by suppressing pro-inflammatory factors p66Shc and ER stress chaperone Bip in diabetic rats

Hepatosteatosis and hepatic insulin resistance are blunted by argirein, an anti-inflammatory agent, through normalizing endoplasmic reticulum stress and apoptosis in diabetic liver

Sildenafil improves diabetic vascular activity through suppressing endothelin receptor A, iNOS and NADPH oxidase which is comparable with the endothelin receptor antagonist CPU0213 in STZ-injected rats

UPREGULATED ENDOTHELIN SYSTEM IN DIABETIC VASCULAR DYSFUNCTION AND EARLY RETINOPATHY IS REVERSED BY CPU0213 AND TOTAL TRITERPENE ACIDS FROM FRUCTUS CORNI

Hypoxia/oxidative stress alters the pharmacokinetics of CPU86017-RS through mitochondrial dysfunction and NADPH oxidase activation

Hypoxia alters pharmacokinetics of argirein because of mitochondrial dysfunction that is alleviated by apocynin

Total triterpene acids, active ingredients from Fructus Corni, attenuate diabetic cardiomyopathy by normalizing ET pathway and expression of FKBP12.6 and SERCA2a in streptozotocin-rats

Apocynin and raisanberine alleviate intermittent hypoxia induced abnormal StAR and 3β-HSD and low testosterone by suppressing endoplasmic reticulum stress and activated p66Shc in rat testes

Stress-induced cardiac insufficiency relating to abnormal leptin and FKBP12.6 is ameliorated by CPU0213, an endothelin receptor antagonist, which is not affected by the CYP3A suppressing effect of erythromycin

CPU86017, a berberine derivative, attenuates cardiac failure through normalizing calcium leakage and downregulated phospholamban and exerting antioxidant activity

Role of endothelin in the effects of isoprenaline on potassium currents and calsequestrin 2 expression in the heart

CPU0213, A NON-SELECTIVE ETA/ETB RECEPTOR ANTAGONIST, IMPROVES PULMONARY ARTERIOLAR REMODELING OF MONOCROTALINE-INDUCED PULMONARY HYPERTENSION IN RATS

Sildenafil and FDP-Sr attenuate diabetic cardiomyopathy by suppressing abnormal expression of myocardial CASQ2, FKBP12.6, and SERCA2a in rats

Raisanberine protected pulmonary arterial rings and cardiac myocytes of rats against hypoxia injury by suppressing NADPH oxidase and calcium influx

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