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The A to Z of modulated cell patterning by mammalian thioredoxin reductases

Free radical biology & medicine, 2018-02, Vol.115, p.484-496

2018

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Bicarbonate is essential for protein-tyrosine phosphatase 1B (PTP1B) oxidation and cellular signaling through EGF-triggered phosphorylation cascades

The Journal of biological chemistry, 2019-08, Vol.294 (33), p.12330-12338

2019

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Redox regulation of PTPN22 affects the severity of T-cell-dependent autoimmune inflammation

eLife, 2022-05, Vol.11

2022

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Thioredoxin reductase 1 and NADPH directly protect protein tyrosine phosphatase 1B from inactivation during H2O2 exposure

The Journal of biological chemistry, 2017-09, Vol.292 (35), p.14371-14380

2017

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Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-β receptor tyrosine kinase signaling

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (33), p.13398-13403

2013

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Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits tumor growth and tumor-derived angiogenesis

Antioxidants & redox signaling, 2015-04, Vol.22 (11), p.938-950

2015

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12/15-lipoxygenase–derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases

Proceedings of the National Academy of Sciences - PNAS, 2010-09, Vol.107 (36), p.15774-15779

2010

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Hypoxia enhances platelet-derived growth factor signaling in the pulmonary vasculature by down-regulation of protein tyrosine phosphatases

American journal of respiratory and critical care medicine, 2011-04, Vol.183 (8), p.1092-1102

2011

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Qualitative Differences in Protection of PTP1B Activity by the Reductive Trx1 or TRP14 Enzyme Systems upon Oxidative Challenges with Polysulfides or H2O2 Together with Bicarbonate

Antioxidants, 2021-01, Vol.10 (1), p.111

2021

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Hypoxia followed by re-oxygenation induces oxidation of tyrosine phosphatases

Cellular signalling, 2011-05, Vol.23 (5), p.820-826

2011

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Oxidation sensitivity of the catalytic cysteine of the protein-tyrosine phosphatases SHP-1 and SHP-2

Free radical biology & medicine, 2007-07, Vol.43 (1), p.100-110

2007

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Endogenous electrophiles and peroxymonocarbonate can link tyrosine phosphorylation cascades with the cytosolic TXNRD1 selenoprotein and the KEAP1/NRF2 system

Current opinion in chemical biology, 2024-12, Vol.83, p.102522, Article 102522

2024

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Regulation of protein tyrosine phosphatase oxidation in cell adhesion and migration

Antioxidants & redox signaling, 2014-05, Vol.20 (13), p.1994-2010

2014

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The mitochondrial reactive oxygen species regulator p66Shc controls PDGF-induced signaling and migration through protein tyrosine phosphatase oxidation

Free radical biology & medicine, 2014-03, Vol.68, p.268-277

2014

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OP-22 - Bicarbonate is required for hydrogen peroxide-dependent inactivation of PTP1B in presence of the Trx system and peroxiredoxin

Free radical biology & medicine, 2018-05, Vol.120, p.S36-S36

2018

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FBXW7/hCDC4 is a general tumor suppressor in human cancer

Cancer research (Chicago, Ill.), 2007-10, Vol.67 (19), p.9006-9012

2007

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Qualitative Differences in Protection of PTP1B Activity by the Reductive Trx1 or TRP14 Enzyme Systems upon Oxidative Challenges with Polysulfides or H 2 O 2 Together with Bicarbonate

Antioxidants, 2021-01, Vol.10 (1)

2021

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84 - Thioredoxin Reductase 1 Directly Protects Protein Tyrosine Phosphatase 1B from Inactivation by H2O2

Free radical biology & medicine, 2016-11, Vol.100, p.S47-S47

2016

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Thioredoxin Reductase 1 Directly Protects Protein Tyrosine Phosphatase 1B from Inactivation by H2O2

Free radical biology & medicine, 2016-11, Vol.100, p.S47

2016

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Bicarbonate is required for hydrogen peroxide-dependent inactivation of PTP1B in presence of the Trx system and peroxiredoxin

FREE RADICAL BIOLOGY AND MEDICINE, 2018, Vol.120, p.S36

2018

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Cell transformation by FLT3 ITD in acute myeloid leukemia involves oxidative inactivation of the tumor suppressor protein-tyrosine phosphatase DEP-1/ PTPRJ

Blood, 2012-05, Vol.119 (19), p.4499-4511

2012

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Abstract 17649: Inhibition of Src Homology 2 Domain-containing Phosphatase 1 (SHP-1) Increases Insulin Sensitivity in High-fat Diet-induced Insulin Resistant C57black6 Mice

Circulation (New York, N.Y.), 2014-11, Vol.130 (suppl_2)

2014

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Interferon alpha-induced apoptosis in tumor cells is mediated through the phosphoinositide 3-kinase/mammalian target of rapamycin signaling pathway

The Journal of biological chemistry, 2004-06, Vol.279 (23), p.24152-24162

2004

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Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-[Beta] receptor tyrosine kinase signaling

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (33), p.13398

2013

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Inhibition of protein tyrosine phosphatases enhances cerebral collateral growth in rats

Journal of molecular medicine (Berlin, Germany), 2014-09, Vol.92 (9), p.983-994

2014

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The A to Z of modulated cell patterning by mammalian thioredoxin reductases

Bicarbonate is essential for protein-tyrosine phosphatase 1B (PTP1B) oxidation and cellular signaling through EGF-triggered phosphorylation cascades

Redox regulation of PTPN22 affects the severity of T-cell-dependent autoimmune inflammation

Thioredoxin reductase 1 and NADPH directly protect protein tyrosine phosphatase 1B from inactivation during H2O2 exposure

Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-β receptor tyrosine kinase signaling

Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits tumor growth and tumor-derived angiogenesis

12/15-lipoxygenase–derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases

Hypoxia enhances platelet-derived growth factor signaling in the pulmonary vasculature by down-regulation of protein tyrosine phosphatases

Qualitative Differences in Protection of PTP1B Activity by the Reductive Trx1 or TRP14 Enzyme Systems upon Oxidative Challenges with Polysulfides or H2O2 Together with Bicarbonate

Hypoxia followed by re-oxygenation induces oxidation of tyrosine phosphatases

Oxidation sensitivity of the catalytic cysteine of the protein-tyrosine phosphatases SHP-1 and SHP-2

Endogenous electrophiles and peroxymonocarbonate can link tyrosine phosphorylation cascades with the cytosolic TXNRD1 selenoprotein and the KEAP1/NRF2 system

Regulation of protein tyrosine phosphatase oxidation in cell adhesion and migration

The mitochondrial reactive oxygen species regulator p66Shc controls PDGF-induced signaling and migration through protein tyrosine phosphatase oxidation

OP-22 - Bicarbonate is required for hydrogen peroxide-dependent inactivation of PTP1B in presence of the Trx system and peroxiredoxin

FBXW7/hCDC4 is a general tumor suppressor in human cancer

Qualitative Differences in Protection of PTP1B Activity by the Reductive Trx1 or TRP14 Enzyme Systems upon Oxidative Challenges with Polysulfides or H 2 O 2 Together with Bicarbonate

84 - Thioredoxin Reductase 1 Directly Protects Protein Tyrosine Phosphatase 1B from Inactivation by H2O2

Thioredoxin Reductase 1 Directly Protects Protein Tyrosine Phosphatase 1B from Inactivation by H2O2

Bicarbonate is required for hydrogen peroxide-dependent inactivation of PTP1B in presence of the Trx system and peroxiredoxin

Cell transformation by FLT3 ITD in acute myeloid leukemia involves oxidative inactivation of the tumor suppressor protein-tyrosine phosphatase DEP-1/ PTPRJ

Abstract 17649: Inhibition of Src Homology 2 Domain-containing Phosphatase 1 (SHP-1) Increases Insulin Sensitivity in High-fat Diet-induced Insulin Resistant C57black6 Mice

Interferon alpha-induced apoptosis in tumor cells is mediated through the phosphoinositide 3-kinase/mammalian target of rapamycin signaling pathway

Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-[Beta] receptor tyrosine kinase signaling

Inhibition of protein tyrosine phosphatases enhances cerebral collateral growth in rats

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