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Genetics, diagnosis and management of colorectal cancer (Review)

Oncology reports, 2015-09, Vol.34 (3), p.1087-1096

2015

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A Potential Role of IL-6/IL-6R in the Development and Management of Colon Cancer

Membranes (Basel), 2021-04, Vol.11 (5), p.312

2021

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Germline Variants in MLH1 and ATM Genes in a Young Patient with MSI-H in a Precancerous Colonic Lesion

International journal of molecular sciences, 2023-03, Vol.24 (6), p.5970

2023

Volltextzugriff (PDF)

Hereditary Colorectal Cancer: State of the Art in Lynch Syndrome

Cancers, 2022-12, Vol.15 (1), p.75

2022

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Implications of Splicing Alterations in the Onset and Phenotypic Variability of a Family with Subclinical Manifestation of Peutz-Jeghers Syndrome: Bioinformatic and Molecular Evidence

International journal of molecular sciences, 2020-11, Vol.21 (21), p.8201

2020

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Novel Implications in Molecular Diagnosis of Lynch Syndrome

Gastroenterology research and practice, 2017-01, Vol.2017, p.2595098-12

2017

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The Role of Colonoscopy in the Management of Individuals with Lynch Syndrome: A Narrative Review

Cancers, 2023-07, Vol.15 (15), p.3780

2023

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The biological complexity of colorectal cancer: insights into biomarkers for early detection and personalized care

Therapeutic Advances in Gastroenterology, 2016-11, Vol.9 (6), p.861-886

2016

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MiR-137 Targets the 3′ Untranslated Region of MSH2: Potential Implications in Lynch Syndrome-Related Colorectal Cancer

Cancers, 2021-09, Vol.13 (18), p.4662

2021

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The Epithelial to Mesenchymal Transition in Colorectal Cancer Progression: The Emerging Role of Succinate Dehydrogenase Alterations and Succinate Accumulation

Biomedicines, 2023-05, Vol.11 (5), p.1428

2023

Volltextzugriff (PDF)

Same MSH2 Gene Mutation But Variable Phenotypes in 2 Families With Lynch Syndrome: Two Case Reports and Review of Genotype-Phenotype Correlation

Clinical medicine insights. Case reports, 2018-01, Vol.11, p.1179547617753943-1179547617753943

2018

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MSH2 Overexpression Due to an Unclassified Variant in 3’-Untranslated Region in a Patient with Colon Cancer

Biomedicines, 2020-06, Vol.8 (6), p.167

2020

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Beta catenin and cytokine pathway dysregulation in patients with manifestations of the "PTEN hamartoma tumor syndrome"

BMC medical genetics, 2012-04, Vol.13 (1), p.28-28, Article 28

2012

Volltextzugriff (PDF)

Genetics, diagnosis and treatment of Lynch syndrome: Old lessons and current challenges

Oncology letters, 2019-03, Vol.17 (3), p.3048-3054

2019

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Coexistence of MLH3 germline variants in colon cancer patients belonging to families with Lynch syndrome-associated brain tumors

Journal of neuro-oncology, 2016-09, Vol.129 (3), p.577-578

2016

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Significance of rare variants in genes involved in the pathogenesis of Lynch syndrome

International journal of molecular medicine, 2022-06, Vol.49 (6), p.1, Article 81

2022

Volltextzugriff (PDF)

Promising Colorectal Cancer Biomarkers for Precision Prevention and Therapy

Cancers, 2019-12, Vol.11 (12), p.1932

2019

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Incomplete Segregation of MSH6 Frameshift Variants with Phenotype of Lynch Syndrome

International journal of molecular sciences, 2017-05, Vol.18 (5), p.999

2017

Volltextzugriff (PDF)

Novel MSH2 splice-site mutation in a young patient with Lynch syndrome

Molecular medicine reports, 2018-05, Vol.17 (5), p.6942-6946

2018

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Characterisation of mesenchymal colon tumour-derived cells in tumourspheres as a model for colorectal cancer progression

International journal of oncology, 2018-12, Vol.53 (6), p.2379-2396

2018

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Wound healing activity and phytochemical screening of purified fractions of Sempervivum tectorum L. leaves on HCT 116

Phytochemical analysis, 2019-09, Vol.30 (5), p.524-534

2019

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Association of low‐risk MSH3 and MSH2 variant alleles with Lynch syndrome: Probability of synergistic effects

International journal of cancer, 2011-10, Vol.129 (7), p.1643-1650

2011

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Multivariate analysis as a method for evaluating the pathogenicity of novel genetic MLH1 variants in patients with colorectal cancer and microsatellite instability

International journal of molecular medicine, 2015-08, Vol.36 (2), p.511-517

2015

Volltextzugriff (PDF)

Same Gene Mutation But Variable Phenotypes in 2 Families With Lynch Syndrome: Two Case Reports and Review of Genotype-Phenotype Correlation

Clinical medicine insights. Case reports, 2018-01, Vol.11

2018

Volltextzugriff (PDF)

Characterization of novel, large duplications in the MSH2 gene of three unrelated Lynch syndrome patients

Cancer genetics, 2018-02, Vol.221, p.19-24

2018

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Genetics, diagnosis and management of colorectal cancer (Review)

A Potential Role of IL-6/IL-6R in the Development and Management of Colon Cancer

Germline Variants in MLH1 and ATM Genes in a Young Patient with MSI-H in a Precancerous Colonic Lesion

Hereditary Colorectal Cancer: State of the Art in Lynch Syndrome

Implications of Splicing Alterations in the Onset and Phenotypic Variability of a Family with Subclinical Manifestation of Peutz-Jeghers Syndrome: Bioinformatic and Molecular Evidence

Novel Implications in Molecular Diagnosis of Lynch Syndrome

The Role of Colonoscopy in the Management of Individuals with Lynch Syndrome: A Narrative Review

The biological complexity of colorectal cancer: insights into biomarkers for early detection and personalized care

MiR-137 Targets the 3′ Untranslated Region of MSH2: Potential Implications in Lynch Syndrome-Related Colorectal Cancer

The Epithelial to Mesenchymal Transition in Colorectal Cancer Progression: The Emerging Role of Succinate Dehydrogenase Alterations and Succinate Accumulation

Same MSH2 Gene Mutation But Variable Phenotypes in 2 Families With Lynch Syndrome: Two Case Reports and Review of Genotype-Phenotype Correlation

MSH2 Overexpression Due to an Unclassified Variant in 3’-Untranslated Region in a Patient with Colon Cancer

Beta catenin and cytokine pathway dysregulation in patients with manifestations of the "PTEN hamartoma tumor syndrome"

Genetics, diagnosis and treatment of Lynch syndrome: Old lessons and current challenges

Coexistence of MLH3 germline variants in colon cancer patients belonging to families with Lynch syndrome-associated brain tumors

Significance of rare variants in genes involved in the pathogenesis of Lynch syndrome

Promising Colorectal Cancer Biomarkers for Precision Prevention and Therapy

Incomplete Segregation of MSH6 Frameshift Variants with Phenotype of Lynch Syndrome

Novel MSH2 splice-site mutation in a young patient with Lynch syndrome

Characterisation of mesenchymal colon tumour-derived cells in tumourspheres as a model for colorectal cancer progression

Wound healing activity and phytochemical screening of purified fractions of Sempervivum tectorum L. leaves on HCT 116

Association of low‐risk MSH3 and MSH2 variant alleles with Lynch syndrome: Probability of synergistic effects

Multivariate analysis as a method for evaluating the pathogenicity of novel genetic MLH1 variants in patients with colorectal cancer and microsatellite instability

Same Gene Mutation But Variable Phenotypes in 2 Families With Lynch Syndrome: Two Case Reports and Review of Genotype-Phenotype Correlation

Characterization of novel, large duplications in the MSH2 gene of three unrelated Lynch syndrome patients

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