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Effects of Dipeptidyl Peptidase-4 Inhibition on Gastrointestinal Function, Meal Appearance, and Glucose Metabolism in Type 2 Diabetes

Diabetes (New York, N.Y.), 2007-05, Vol.56 (5), p.1475-1480

2007

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Vildagliptin Enhances Islet Responsiveness to Both Hyper- and Hypoglycemia in Patients with Type 2 Diabetes

The journal of clinical endocrinology and metabolism, 2009-04, Vol.94 (4), p.1236-1243

2009

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The Dipeptidyl Peptidase IV Inhibitor Vildagliptin Suppresses Endogenous Glucose Production and Enhances Islet Function after Single-Dose Administration in Type 2 Diabetic Patients

The journal of clinical endocrinology and metabolism, 2007-04, Vol.92 (4), p.1249-1255

2007

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1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: A Potent, Selective, and Orally Bioavailable Dipeptidyl Peptidase IV Inhibitor with Antihyperglycemic Properties

Journal of medicinal chemistry, 2003-06, Vol.46 (13), p.2774-2789

2003

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Treatment with the Dipeptidyl Peptidase-4 Inhibitor Vildagliptin Improves Fasting Islet-Cell Function in Subjects with Type 2 Diabetes

The journal of clinical endocrinology and metabolism, 2009-01, Vol.94 (1), p.81-88

2009

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Characterization of the Influence of Vildagliptin on Model-Assessed β-Cell Function in Patients with Type 2 Diabetes and Mild Hyperglycemia

The journal of clinical endocrinology and metabolism, 2008-01, Vol.93 (1), p.103-109

2008

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The Effect of Food on the Oral Bioavailability and the Pharmacodynamic Actions of the Insulinotropic Agent Nateglinide in Healthy Subjects

Journal of clinical pharmacology, 1999-02, Vol.39 (2), p.172-179

1999

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Pharmacodynamics of Vildagliptin in Patients With Type 2 Diabetes During OGTT

Journal of clinical pharmacology, 2007-05, Vol.47 (5), p.633-641

2007

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Glucosamine inhibits glucokinase in vitro and produces a glucose-specific impairment of in vivo insulin secretion in rats

Diabetes (New York, N.Y.), 1994-10, Vol.43 (10), p.1173-1179

1994

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Importance of early insulin secretion: Comparison of nateglinide and glyburide in previously diet-treated patients with type 2 diabetes

Diabetes care, 2001-06, Vol.24 (6), p.983-988

2001

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Clinical measures of islet function: usefulness to characterize defects in diabetes

Current diabetes reviews, 2008-05, Vol.4 (2), p.129-145

2008

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Portal glucose infusion exerts an incretin effect associated with changes in pancreatic neural activity in conscious dogs

Metabolism, clinical and experimental, 2002-10, Vol.51 (10), p.1324-1330

2002

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Human galanin: Primary structure and indentification of two molecular forms

FEBS letters, 1991-06, Vol.283 (2), p.189-194

1991

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Direct quantification of norepinephrine spillover and hormone output from the pancreas of the conscious dog

American journal of physiology: endocrinology and metabolism, 1997-05, Vol.272 (5), p.E746-E755

1997

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1-[2-[(5-Cyanopyridin-2-yl)amino]ethylamino]acetyl-2-(S)-pyrrolidinecarbonitrile: A Potent, Selective, and Orally Bioavailable Dipeptidyl Peptidase IV Inhibitor with Antihyperglycemic Properties

Journal of medicinal chemistry, 2002-06, Vol.45 (12), p.2362-2365

2002

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Importance of Early Insulin Secretion

Diabetes care, 2001-06, Vol.24 (6), p.983-988

2001

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Evidence that vasoactive intestinal polypeptide is a parasympathetic neurotransmitter in the endocrine pancreas in dogs

Regulatory peptides, 1997-08, Vol.71 (3), p.163-170

1997

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Lactate clamp: a method to measure lactate utilization in vivo

American journal of physiology: endocrinology and metabolism, 1998-10, Vol.275 (4), p.E729-E733

1998

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Pharmacological Strategies for Reduction of Lipid Availability

Annals of the New York Academy of Sciences, 1997-09, Vol.827 (1), p.231-245

1997

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Pancreatic beta-cell K(ATP) channel activity and membrane-binding studies with nateglinide: A comparison with sulfonylureas and repaglinide

The Journal of pharmacology and experimental therapeutics, 2000-05, Vol.293 (2), p.444

2000

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Glucose‐dependent and Glucose‐sensitizing Insulinotropic Effect of Nateglinide: Comparisonto Sulfonylureas and Repaglinide

Journal of diabetes research, 2001-01, Vol.2 (1), p.63-72

2001

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Effectiveness of Nateglinide on In Vitro Insulin Secretion from Rat Pancreatic IsletsDesensitized to Sulfonylureas

Journal of diabetes research, 2001-01, Vol.2 (1), p.73-79

2001

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Tissue selectivity of antidiabetic agent nateglinide: study on cardiovascular and beta-cell K(ATP) channels

The Journal of pharmacology and experimental therapeutics, 1999-12, Vol.291 (3), p.1372

1999

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Presence of galanin in human pancreatic nerves and inhibition of insulin secretion from isolated human islets

Cell and tissue research, 1991-05, Vol.264 (2), p.263-267

1991

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Role for autonomic nervous system to increase pancreatic glucagon secretion during marked insulin-induced hypoglycemia in dogs

Diabetes (New York, N.Y.), 1991-09, Vol.40 (9), p.1107-1114

1991

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Effects of Dipeptidyl Peptidase-4 Inhibition on Gastrointestinal Function, Meal Appearance, and Glucose Metabolism in Type 2 Diabetes

Vildagliptin Enhances Islet Responsiveness to Both Hyper- and Hypoglycemia in Patients with Type 2 Diabetes

The Dipeptidyl Peptidase IV Inhibitor Vildagliptin Suppresses Endogenous Glucose Production and Enhances Islet Function after Single-Dose Administration in Type 2 Diabetic Patients

1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: A Potent, Selective, and Orally Bioavailable Dipeptidyl Peptidase IV Inhibitor with Antihyperglycemic Properties

Treatment with the Dipeptidyl Peptidase-4 Inhibitor Vildagliptin Improves Fasting Islet-Cell Function in Subjects with Type 2 Diabetes

Characterization of the Influence of Vildagliptin on Model-Assessed β-Cell Function in Patients with Type 2 Diabetes and Mild Hyperglycemia

The Effect of Food on the Oral Bioavailability and the Pharmacodynamic Actions of the Insulinotropic Agent Nateglinide in Healthy Subjects

Pharmacodynamics of Vildagliptin in Patients With Type 2 Diabetes During OGTT

Glucosamine inhibits glucokinase in vitro and produces a glucose-specific impairment of in vivo insulin secretion in rats

Importance of early insulin secretion: Comparison of nateglinide and glyburide in previously diet-treated patients with type 2 diabetes

Clinical measures of islet function: usefulness to characterize defects in diabetes

Portal glucose infusion exerts an incretin effect associated with changes in pancreatic neural activity in conscious dogs

Human galanin: Primary structure and indentification of two molecular forms

Direct quantification of norepinephrine spillover and hormone output from the pancreas of the conscious dog

1-[2-[(5-Cyanopyridin-2-yl)amino]ethylamino]acetyl-2-(S)-pyrrolidinecarbonitrile: A Potent, Selective, and Orally Bioavailable Dipeptidyl Peptidase IV Inhibitor with Antihyperglycemic Properties

Importance of Early Insulin Secretion

Evidence that vasoactive intestinal polypeptide is a parasympathetic neurotransmitter in the endocrine pancreas in dogs

Lactate clamp: a method to measure lactate utilization in vivo

Pharmacological Strategies for Reduction of Lipid Availability

Pancreatic beta-cell K(ATP) channel activity and membrane-binding studies with nateglinide: A comparison with sulfonylureas and repaglinide

Glucose‐dependent and Glucose‐sensitizing Insulinotropic Effect of Nateglinide: Comparisonto Sulfonylureas and Repaglinide

Effectiveness of Nateglinide on In Vitro Insulin Secretion from Rat Pancreatic IsletsDesensitized to Sulfonylureas

Tissue selectivity of antidiabetic agent nateglinide: study on cardiovascular and beta-cell K(ATP) channels

Presence of galanin in human pancreatic nerves and inhibition of insulin secretion from isolated human islets

Role for autonomic nervous system to increase pancreatic glucagon secretion during marked insulin-induced hypoglycemia in dogs

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