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The war against pancreatic cancer in 2020 - advances on all fronts

Nature reviews. Gastroenterology & hepatology, 2021-02, Vol.18 (2), p.99-100

2021

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Early Intra-Acinar Events in Pathogenesis of Pancreatitis

Gastroenterology (New York, N.Y. 1943), 2019-05, Vol.156 (7), p.1979-1993

2019

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Inactivation of Cancer-Associated-Fibroblasts Disrupts Oncogenic Signaling in Pancreatic Cancer Cells and Promotes Its Regression

Cancer research (Chicago, Ill.), 2018-03, Vol.78 (5), p.1321-1333

2018

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The Role of the Microbiome in Immunologic Development and its Implication For Pancreatic Cancer Immunotherapy

Gastroenterology (New York, N.Y. 1943), 2019-05, Vol.156 (7), p.2097-2115.e2

2019

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Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma: An Update on Heterogeneity and Therapeutic Targeting

International journal of molecular sciences, 2021-12, Vol.22 (24), p.13408

2021

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Targeting tumor-intrinsic hexosamine biosynthesis sensitizes pancreatic cancer to anti-PD1 therapy

The Journal of clinical investigation, 2020-01, Vol.130 (1), p.451-465

2020

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Gut Microbiota Promotes Tumor Growth in Mice by Modulating Immune Response

Gastroenterology (New York, N.Y. 1943), 2018-07, Vol.155 (1), p.33-37.e6

2018

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ER stress sensor, glucose regulatory protein 78 (GRP78) regulates redox status in pancreatic cancer thereby maintaining "stemness"

Cell death & disease, 2019-02, Vol.10 (2), p.132-132, Article 132

2019

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New Insights Into the Cancer-Microbiome-Immune Axis: Decrypting a Decade of Discoveries

Frontiers in immunology, 2021-02, Vol.12, p.622064

2021

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Gamma Secretase Inhibitors in Cancer: A Current Perspective on Clinical Performance

The oncologist (Dayton, Ohio), 2021-04, Vol.26 (4), p.e608-e621

2021

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Impaired Synthesis of Stromal Components in Response to Minnelide Improves Vascular Function, Drug Delivery, and Survival in Pancreatic Cancer

Clinical cancer research, 2016-01, Vol.22 (2), p.415-425

2016

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Relevance of Animal Models of Pancreatic Cancer and Pancreatitis to Human Disease

Gastroenterology (New York, N.Y. 1943), 2013-06, Vol.144 (6), p.1194-1198

2013

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Tumor-targeted silencing of the peptide transporter TAP induces potent antitumor immunity

Nature communications, 2019-08, Vol.10 (1), p.3773-13, Article 3773

2019

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Release of cathepsin-B in cytosol causes cell death in acute pancreatitis

Gastroenterology (New York, N.Y. 1943), 2016-10, Vol.151 (4), p.747-758.e5

2016

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A preclinical evaluation of Minnelide as a therapeutic agent against pancreatic cancer

Science translational medicine, 2012-10, Vol.4 (156), p.156ra139

2012

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NFκB-Mediated Invasiveness in CD133 + Pancreatic TICs Is Regulated by Autocrine and Paracrine Activation of IL1 Signaling

Molecular cancer research, 2018-01, Vol.16 (1), p.162-172

2018

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CD133 initiates tumors, induces epithelial-mesenchymal transition and increases metastasis in pancreatic cancer

Oncotarget, 2015-04, Vol.6 (10), p.8313-8322

2015

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Inhibition of hypoxic response decreases stemness and reduces tumorigenic signaling due to impaired assembly of HIF1 transcription complex in pancreatic cancer

Scientific reports, 2017-08, Vol.7 (1), p.7872-11, Article 7872

2017

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GRP78‐mediated antioxidant response and ABC transporter activity confers chemoresistance to pancreatic cancer cells

Molecular oncology, 2018-09, Vol.12 (9), p.1498-1512

2018

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Diethyldithiocarbamate-ferrous oxide nanoparticles inhibit human and mouse glioblastoma stemness: aldehyde dehydrogenase 1A1 suppression and ferroptosis induction

Frontiers in pharmacology, 2024-04, Vol.15, p.1363511-1363511

2024

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Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70

Cancer research (Chicago, Ill.), 2007-10, Vol.67 (19), p.9407-9416

2007

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Pre-clinical evaluation of Minnelide as a therapy for acute myeloid leukemia

Journal of translational medicine, 2019-05, Vol.17 (1), p.163-9, Article 163

2019

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Heat shock protein 70 increases tumorigenicity and inhibits apoptosis in pancreatic adenocarcinoma

Cancer research (Chicago, Ill.), 2007-01, Vol.67 (2), p.616-625

2007

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Triptolide Induces Cell Death in Pancreatic Cancer Cells by Apoptotic and Autophagic Pathways

Gastroenterology (New York, N.Y. 1943), 2010-08, Vol.139 (2), p.598-608

2010

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Why Do Long-Distance Travelers Have Improved Pancreatectomy Outcomes?

Journal of the American College of Surgeons, 2017-08, Vol.225 (2), p.216-225

2017

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The war against pancreatic cancer in 2020 - advances on all fronts

Early Intra-Acinar Events in Pathogenesis of Pancreatitis

Inactivation of Cancer-Associated-Fibroblasts Disrupts Oncogenic Signaling in Pancreatic Cancer Cells and Promotes Its Regression

The Role of the Microbiome in Immunologic Development and its Implication For Pancreatic Cancer Immunotherapy

Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma: An Update on Heterogeneity and Therapeutic Targeting

Targeting tumor-intrinsic hexosamine biosynthesis sensitizes pancreatic cancer to anti-PD1 therapy

Gut Microbiota Promotes Tumor Growth in Mice by Modulating Immune Response

ER stress sensor, glucose regulatory protein 78 (GRP78) regulates redox status in pancreatic cancer thereby maintaining "stemness"

New Insights Into the Cancer-Microbiome-Immune Axis: Decrypting a Decade of Discoveries

Gamma Secretase Inhibitors in Cancer: A Current Perspective on Clinical Performance

Impaired Synthesis of Stromal Components in Response to Minnelide Improves Vascular Function, Drug Delivery, and Survival in Pancreatic Cancer

Relevance of Animal Models of Pancreatic Cancer and Pancreatitis to Human Disease

Tumor-targeted silencing of the peptide transporter TAP induces potent antitumor immunity

Release of cathepsin-B in cytosol causes cell death in acute pancreatitis

A preclinical evaluation of Minnelide as a therapeutic agent against pancreatic cancer

NFκB-Mediated Invasiveness in CD133 + Pancreatic TICs Is Regulated by Autocrine and Paracrine Activation of IL1 Signaling

CD133 initiates tumors, induces epithelial-mesenchymal transition and increases metastasis in pancreatic cancer

Inhibition of hypoxic response decreases stemness and reduces tumorigenic signaling due to impaired assembly of HIF1 transcription complex in pancreatic cancer

GRP78‐mediated antioxidant response and ABC transporter activity confers chemoresistance to pancreatic cancer cells

Diethyldithiocarbamate-ferrous oxide nanoparticles inhibit human and mouse glioblastoma stemness: aldehyde dehydrogenase 1A1 suppression and ferroptosis induction

Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70

Pre-clinical evaluation of Minnelide as a therapy for acute myeloid leukemia

Heat shock protein 70 increases tumorigenicity and inhibits apoptosis in pancreatic adenocarcinoma

Triptolide Induces Cell Death in Pancreatic Cancer Cells by Apoptotic and Autophagic Pathways

Why Do Long-Distance Travelers Have Improved Pancreatectomy Outcomes?

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